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AP3S1 and SCARB2
Number of citations of the paper that reports this interaction (PMID
12370188
)
11
Data Source:
HPRD
(in vitro)
AP3S1
SCARB2
Gene Name
adaptor-related protein complex 3, sigma 1 subunit
scavenger receptor class B, member 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Apparatus
AP-type Membrane Coat Adaptor Complex
AP-3 Adaptor Complex
Transport Vesicle
Cytoplasmic Vesicle Membrane
Lysosomal Membrane
Focal Adhesion
Membrane
Integral Component Of Membrane
Lysosomal Lumen
Extracellular Vesicular Exosome
Molecular Function
Transporter Activity
Protein Binding
Protein Transporter Activity
Receptor Activity
Protein Binding
Enzyme Binding
Biological Process
Intracellular Protein Transport
Anterograde Axon Cargo Transport
Insulin Receptor Signaling Pathway
Anterograde Synaptic Vesicle Transport
Protein Targeting To Lysosome
Cell Adhesion
Pathways
Golgi Associated Vesicle Biogenesis
trans-Golgi Network Vesicle Budding
Clathrin derived vesicle budding
Drugs
Diseases
GWAS
Parkinson's disease (
21738487
)
Protein-Protein Interactions
7 interactors:
AP3B2
AP3D1
AP3S2
IRS1
RUFY1
SCARB2
SLC30A3
2 interactors:
AP3S1
THBS1
Entrez ID
1176
950
HPRD ID
03298
03772
Ensembl ID
ENSG00000138760
Uniprot IDs
Q92572
Q14108
PDB IDs
Enriched GO Terms of Interacting Partners
?
Anterograde Synaptic Vesicle Transport
Anterograde Axon Cargo Transport
Axon Cargo Transport
Regulation Of Sequestering Of Zinc Ion
Protein Localization
Synaptic Vesicle Transport
Microtubule-based Transport
Cytoskeleton-dependent Intracellular Transport
Cellular Protein Localization
Protein Transport
Establishment Of Protein Localization
Establishment Of Vesicle Localization
Vesicle Localization
Intracellular Protein Transport
Microtubule-based Movement
Establishment Of Organelle Localization
Organelle Localization
Cellular Localization
Protein Localization To Organelle
Vesicle-mediated Transport
Transport
Synaptic Transmission
Intracellular Transport
Synaptic Vesicle Membrane Organization
Regulation Of Ion Homeostasis
Microtubule-based Process
Eye Pigment Biosynthetic Process
Establishment Of Localization In Cell
Cell-cell Signaling
Positive Regulation Of NK T Cell Differentiation
Eye Pigmentation
Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib
Endosome To Melanosome Transport
Pigment Granule Maturation
Cellular Pigment Accumulation
Positive Regulation Of Fatty Acid Beta-oxidation
Protein Targeting To Lysosome
Positive Regulation Of Glycogen Biosynthetic Process
Protein Localization To Lysosome
Positive Regulation Of Glucose Import In Response To Insulin Stimulus
Positive Regulation Of Fatty Acid Oxidation
Regulation Of Fatty Acid Beta-oxidation
Insulin-like Growth Factor Receptor Signaling Pathway
Regulation Of Glucose Import In Response To Insulin Stimulus
Melanosome Organization
Protein Targeting To Vacuole
JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway
Pigment Granule Organization
Phosphatidylinositol 3-kinase Signaling
Movement Of Cell Or Subcellular Component
Negative Regulation Of CGMP-mediated Signaling
Negative Regulation Of Dendritic Cell Antigen Processing And Presentation
Engulfment Of Apoptotic Cell
Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II
Negative Regulation Of Endothelial Cell Chemotaxis
Negative Regulation Of Nitric Oxide Mediated Signal Transduction
Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport
Negative Regulation Of Antigen Processing And Presentation
Regulation Of CGMP-mediated Signaling
Positive Regulation Of Macrophage Chemotaxis
Negative Regulation Of Plasminogen Activation
Positive Regulation Of Transforming Growth Factor Beta1 Production
Negative Regulation Of Fibrinolysis
Positive Regulation Of Fibroblast Migration
Protein O-linked Fucosylation
Positive Regulation Of Endothelial Cell Apoptotic Process
Positive Regulation Of Macrophage Activation
Cellular Response To Nitric Oxide
Chronic Inflammatory Response
Phagocytosis, Engulfment
Regulation Of Fibrinolysis
Regulation Of Macrophage Chemotaxis
Positive Regulation Of Tumor Necrosis Factor Biosynthetic Process
Response To Nitric Oxide
Growth Plate Cartilage Development
Membrane Invagination
Regulation Of Tumor Necrosis Factor Biosynthetic Process
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Response To Magnesium Ion
Response To Hormone
Negative Regulation Of Focal Adhesion Assembly
Positive Regulation Of Transforming Growth Factor Beta Production
Anterograde Synaptic Vesicle Transport
Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Interleukin-12 Production
Cellular Response To Reactive Nitrogen Species
Behavioral Response To Pain
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Lipid Transport
Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Macrophage Activation
Negative Regulation Of Chemotaxis
Endochondral Bone Growth
Anterograde Axon Cargo Transport
Regulation Of CGMP Metabolic Process
Negative Regulation Of Endothelial Cell Proliferation
Positive Regulation Of Blood Coagulation
Apoptotic Cell Clearance
Regulation Of Fibroblast Migration
Tagcloud
?
advent
coming
cumulative
deep
discovered
drive
estimates
etiology
extensively
familial
give
greatest
harboring
improvements
loci
lrrk2
mapt
nominated
parkinson
perhaps
personalized
replicated
rit2
snca
sporadic
srebf1
ultimately
variants
warranted
Tagcloud (Difference)
?
advent
coming
cumulative
deep
discovered
drive
estimates
etiology
extensively
familial
give
greatest
harboring
improvements
loci
lrrk2
mapt
nominated
parkinson
perhaps
personalized
replicated
rit2
snca
sporadic
srebf1
ultimately
variants
warranted
Tagcloud (Intersection)
?