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GPRASP2 and RABGEF1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
GPRASP2
RABGEF1
Description
G protein-coupled receptor associated sorting protein 2
RAB guanine nucleotide exchange factor 1
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Nucleolus
Cytoplasm
Endosome
Early Endosome
Cytosol
Endocytic Vesicle
Dendrite
Early Endosome Membrane
Vesicle
Recycling Endosome
Presynaptic Endosome
Molecular Function
Amyloid-beta Binding
G Protein-coupled Receptor Binding
Protein Binding
DNA Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Zinc Ion Binding
Small GTPase Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Biological Process
Hematopoietic Stem Cell Homeostasis
Negative Regulation Of Leukocyte Migration
Protein Targeting To Membrane
Endocytosis
Receptor-mediated Endocytosis
Ras Protein Signal Transduction
Protein Transport
Vesicle-mediated Transport
Endosomal Transport
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Mast Cell Cytokine Production
Negative Regulation Of Mast Cell Activation
Kit Signaling Pathway
Mast Cell Degranulation
Negative Regulation Of Mast Cell Degranulation
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Receptor-mediated Endocytosis
Negative Regulation Of Inflammatory Response
Establishment Of Localization In Cell
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Mast Cell Migration
Dendritic Transport
Negative Regulation Of Kit Signaling Pathway
Pathways
TBC/RABGAPs
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Aortic root size (
21223598
)
Central corneal thickness (
29760442
32528159
)
Interacting Genes
52 interacting genes:
ADRB1
ARHGEF6
BARD1
CALCR
CAVIN3
CBX8
CCDC146
CEP126
CFAP206
CHRM1
CHRM2
DISC1
DSCR9
EFCAB3
FAM124B
FCHSD2
FOXD4L1
FRAT1
GADD45GIP1
HAP1
HRH2
HTR7
HTT
LRIF1
MBD3L2
MICU2
MYOT
NOL4L-DT
PIH1D2
PLAC9
PRPF3
PTN
RABGEF1
REX1BD
RHPN1
RNF8
RPS6KA5
SAPCD2
SEZ6L
SH2D4A
SREK1
STMN2
TBRG4
TCF25
TSPOAP1
TTC23
TXN
TXN2
USP20
ZC2HC1C
ZFYVE26
ZNF688
49 interacting genes:
ABI2
ANKRD29
AP1G1
ARRDC3
BLOC1S6
CCHCR1
CDC37
CIPC
DAZAP2
DCTN2
DGCR6
DNAJC5
EMILIN1
GGA1
GGA2
GPRASP2
HOOK2
HRAS
IHO1
KXD1
MID2
MON1A
MON1B
OIP5
RAB33B
RAB4A
RABEP1
RAD23A
RASAL3
RNF11
RNF168
RPS27A
SESTD1
SNAPIN
SPART
SSX3
TCHP
TEAD4
THOC1
TRIM15
TRIM54
TXN2
UBA52
UBB
UBE2D1
UBE2D3
WASHC1
YWHAB
ZC2HC1C
Entrez ID
114928
27342
HPRD ID
06612
11477
Ensembl ID
ENSG00000158301
ENSG00000154710
Uniprot IDs
B3KW05
Q96D09
A8K3R3
B3KMF1
Q9UJ41
PDB IDs
1TXU
2C7M
2C7N
2OT3
4N3X
4N3Y
4N3Z
4Q9U
Enriched GO Terms of Interacting Partners
?
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Chemical Synaptic Transmission
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Trans-synaptic Signaling
G Protein-coupled Acetylcholine Receptor Activity
Synaptic Signaling
Neuromuscular Synaptic Transmission
Regulation Of Protein Export From Nucleus
Negative Regulation Of Protein Export From Nucleus
Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway
Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway
Microtubule Cytoskeleton Organization
Cholinergic Synapse
Dendrite
Establishment Of Protein Localization
Protein Transport
Vesicle-mediated Transport
Intracellular Protein Localization
Protein Binding
Adipose Tissue Development
Protein Tag Activity
BLOC-1 Complex
Establishment Of Localization In Cell
Intracellular Transport
Ubiquitin Protein Ligase Binding
Recycling Endosome
Connective Tissue Development
Endosome
Protein Ubiquitination
Cellular Localization
Ubiquitin Protein Ligase Activity
Mon1-Ccz1 Complex
Vacuolar Transport
Organelle Transport Along Microtubule
Protein Modification By Small Protein Conjugation
Cytoplasm
Vesicle-mediated Transport In Synapse
Melanosome Organization
Vesicle
Endosome Membrane
Post-Golgi Vesicle-mediated Transport
Pigment Granule Organization
Modification-dependent Protein Catabolic Process
Ubiquitin Binding
Protein Localization To Ciliary Membrane
Regulation Of Lysosome Size
BORC Complex
Cytoskeleton-dependent Intracellular Transport
Early Endosome Membrane
Microvesicle
Protein Targeting
Early Endosome
Endosome To Melanosome Transport
Fat Pad Development
Regulation Of Endosome Size
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Cytosol
Post-translational Protein Modification
Vesicle-mediated Transport To The Plasma Membrane
Cytoplasmic Side Of Lysosomal Membrane
Proteolysis Involved In Protein Catabolic Process
Golgi To Plasma Membrane Transport
Intracellular Protein Transport
Secretion By Cell
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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