GPRASP2 and ZFYVE26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPRASP2	ZFYVE26
Description		G protein-coupled receptor associated sorting protein 2	zinc finger FYVE-type containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Cytoplasm Lysosome Lysosomal Membrane Early Endosome Late Endosome Centrosome Cytoskeleton Midbody
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	Protein Binding Zinc Ion Binding Lipid Binding Protein Kinase Binding Phosphatidylinositol-3-phosphate Binding Metal Ion Binding
	Biological Process	Hematopoietic Stem Cell Homeostasis	Mitotic Cytokinesis Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Damage Response Lysosome Organization Regulation Of Cytokinesis Cell Division Autophagosome Organization
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS			Amyotrophic lateral sclerosis (sporadic) ( 24529757) Asthma ( 31959851) Asthma (childhood onset) ( 31036433)
Interacting Genes		52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 DSCR9 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688	36 interacting genes: ALAS1 ASB15 CBY2 CCDC125 CCDC136 CEP44 CFTR GOLGA2 GPRASP2 HMBOX1 HNRNPC HOOK2 KRT15 KRT27 KRT34 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 MAGED1 MDFI PLEKHF2 PNMA1 PNMA5 PPP1R16A PRDM6 SPAG5 SSX2IP TADA2A TCEANC TDO2 TFIP11 TRAF1 TTC23 USHBP1 USP20
Entrez ID		114928	23503
HPRD ID		06612	15734
Ensembl ID		ENSG00000158301	ENSG00000072121
Uniprot IDs		B3KW05 Q96D09	Q68DK2
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Trans-synaptic Signaling G Protein-coupled Acetylcholine Receptor Activity Synaptic Signaling Neuromuscular Synaptic Transmission Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Export From Nucleus Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Microtubule Cytoskeleton Organization Cholinergic Synapse Dendrite	Keratin Filament Intermediate Filament Identical Protein Binding Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Centrosome Cycle
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