GPRASP2 and EFCAB3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPRASP2	EFCAB3
Description		G protein-coupled receptor associated sorting protein 2	EF-hand calcium binding domain 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Hematopoietic Stem Cell Homeostasis
Pathways
Drugs
Diseases
GWAS			Objective response to lithium treatment ( 26503763)
Interacting Genes		52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 DSCR9 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688	9 interacting genes: CBY2 GPRASP2 HPRT1 KRT34 KRT35 OXER1 SPECC1L TTC23 WWP2
Entrez ID		114928	146779
HPRD ID		06612	08077
Ensembl ID		ENSG00000158301	ENSG00000172421
Uniprot IDs		B3KW05 Q96D09	Q8N7B9
PDB IDs
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Trans-synaptic Signaling G Protein-coupled Acetylcholine Receptor Activity Synaptic Signaling Neuromuscular Synaptic Transmission Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Export From Nucleus Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Microtubule Cytoskeleton Organization Cholinergic Synapse Dendrite	Guanine Salvage Hypoxanthine Salvage Hypoxanthine Phosphoribosyltransferase Activity Guanine Phosphoribosyltransferase Activity Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Neural Crest Cell Delamination 5-hydroxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5(S)-hydroxyperoxy-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding 5-oxo-6E,8Z,11Z,14Z-icosatetraenoic Acid Binding Adenine Metabolic Process Hypoxanthine Biosynthetic Process Hypoxanthine Metabolic Process Anterior Neural Tube Closure Guanine Metabolic Process GMP Salvage GMP Catabolic Process IMP Salvage Positive Regulation Of Dopamine Metabolic Process AMP Salvage Intermediate Filament Negative Regulation Of Potassium Ion Export Across Plasma Membrane Purine Ribonucleoside Salvage Structural Molecule Activity
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