GPRASP2 and HTR7

Number of citations of the paper that reports this interaction (PubMedID 15086532)
0

Data Source:
HPRD (in vitro)

		GPRASP2	HTR7
Description		G protein-coupled receptor associated sorting protein 2	5-hydroxytryptamine receptor 7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleoplasm Plasma Membrane Cilium Membrane Dendrite Trans-Golgi Network Membrane Synapse
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	G Protein-coupled Receptor Activity G Protein-coupled Serotonin Receptor Activity Protein Binding Neurotransmitter Receptor Activity Serotonin Receptor Activity
	Biological Process	Hematopoietic Stem Cell Homeostasis	Smooth Muscle Contraction Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Adenylate Cyclase-activating Serotonin Receptor Signaling Pathway Chemical Synaptic Transmission Circadian Rhythm Blood Circulation Vasoconstriction G Protein-coupled Serotonin Receptor Signaling Pathway
Pathways			Serotonin receptors G alpha (s) signalling events
Drugs			Ziprasidone Methysergide Cabergoline Zolmitriptan Amitriptyline Clozapine Loxapine Cyproheptadine Imipramine Chlorpromazine Haloperidol Amoxapine Lisuride Paroxetine Risperidone Epinastine Cyclobenzaprine Maprotiline Dopamine Ergoloid mesylate Bromocriptine Quetiapine Aripiprazole Chlorprothixene Paliperidone Iloperidone Lofexidine Mianserin Asenapine Amisulpride Lurasidone Vortioxetine Zotepine Setiptiline Dihydroergocornine Gilteritinib Tiapride Dihydroergocristine SB-269970 Aripiprazole lauroxil
Diseases
GWAS			Alzheimer disease and age of onset ( 26830138) Liver fibrogenesis (alpha smooth muscle actin levels) ( 32953199) Midgestational total 25-hydroxyvitamin D levels (maternal genetic effect) ( 32047095) White matter microstructure (global fractional anisotropy) ( 24736177)
Interacting Genes		52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 DSCR9 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688	2 interacting genes: GPRASP1 GPRASP2
Entrez ID		114928	3363
HPRD ID		06612	01639
Ensembl ID		ENSG00000158301	ENSG00000148680
Uniprot IDs		B3KW05 Q96D09	P34969
PDB IDs			7XTC
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Trans-synaptic Signaling G Protein-coupled Acetylcholine Receptor Activity Synaptic Signaling Neuromuscular Synaptic Transmission Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Export From Nucleus Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Microtubule Cytoskeleton Organization Cholinergic Synapse Dendrite	G Protein-coupled Receptor Catabolic Process Receptor Catabolic Process Hematopoietic Stem Cell Homeostasis
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