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RABGEF1 and MON1B
Number of citations of the paper that reports this interaction (PubMedID
20434987
)
0
Data Source:
BioGRID
(pull down)
RABGEF1
MON1B
Description
RAB guanine nucleotide exchange factor 1
MON1 vesicular trafficking associated B
Image
No pdb structure
GO Annotations
Cellular Component
Nucleolus
Cytoplasm
Endosome
Early Endosome
Cytosol
Endocytic Vesicle
Dendrite
Early Endosome Membrane
Vesicle
Recycling Endosome
Presynaptic Endosome
Cytoplasm
Mon1-Ccz1 Complex
Molecular Function
DNA Binding
Guanyl-nucleotide Exchange Factor Activity
Protein Binding
Zinc Ion Binding
Small GTPase Binding
Metal Ion Binding
Ubiquitin Protein Ligase Activity
Protein Binding
Biological Process
Negative Regulation Of Leukocyte Migration
Protein Targeting To Membrane
Endocytosis
Receptor-mediated Endocytosis
Ras Protein Signal Transduction
Protein Transport
Vesicle-mediated Transport
Endosomal Transport
Negative Regulation Of Interleukin-6 Production
Negative Regulation Of Mast Cell Cytokine Production
Negative Regulation Of Mast Cell Activation
Kit Signaling Pathway
Mast Cell Degranulation
Negative Regulation Of Mast Cell Degranulation
Negative Regulation Of Ras Protein Signal Transduction
Negative Regulation Of Receptor-mediated Endocytosis
Negative Regulation Of Inflammatory Response
Establishment Of Localization In Cell
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Mast Cell Migration
Dendritic Transport
Negative Regulation Of Kit Signaling Pathway
Protein Targeting To Vacuole
Vesicle-mediated Transport
Early Viral Transcription
Late Viral Transcription
Pathways
TBC/RABGAPs
RAB GEFs exchange GTP for GDP on RABs
RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS
Aortic root size (
21223598
)
Central corneal thickness (
29760442
32528159
)
Antidepressant treatment resistance (> 2 drugs prescribed) (
30700811
)
Immune response to measles-mumps-rubella vaccine (
24811271
)
Metabolite levels (
23823483
)
Multisite chronic pain (
31194737
33830993
)
Number of sexual partners (
30643258
)
Interacting Genes
49 interacting genes:
ABI2
ANKRD29
AP1G1
ARRDC3
BLOC1S6
CCHCR1
CDC37
CIPC
DAZAP2
DCTN2
DGCR6
DNAJC5
EMILIN1
GGA1
GGA2
GPRASP2
HOOK2
HRAS
IHO1
KXD1
MID2
MON1A
MON1B
OIP5
RAB33B
RAB4A
RABEP1
RAD23A
RASAL3
RNF11
RNF168
RPS27A
SESTD1
SNAPIN
SPART
SSX3
TCHP
TEAD4
THOC1
TRIM15
TRIM54
TXN2
UBA52
UBB
UBE2D1
UBE2D3
WASHC1
YWHAB
ZC2HC1C
6 interacting genes:
RABGEF1
VPS11
VPS16
VPS18
VPS33A
VPS41
Entrez ID
27342
22879
HPRD ID
11477
12342
Ensembl ID
ENSG00000154710
ENSG00000103111
Uniprot IDs
A8K3R3
B3KMF1
Q9UJ41
B4DKA0
E7EW32
Q6ZR87
Q7L1V2
PDB IDs
1TXU
2C7M
2C7N
2OT3
4N3X
4N3Y
4N3Z
4Q9U
Enriched GO Terms of Interacting Partners
?
Establishment Of Protein Localization
Protein Transport
Vesicle-mediated Transport
Intracellular Protein Localization
Protein Binding
Adipose Tissue Development
Protein Tag Activity
BLOC-1 Complex
Establishment Of Localization In Cell
Intracellular Transport
Ubiquitin Protein Ligase Binding
Recycling Endosome
Connective Tissue Development
Endosome
Protein Ubiquitination
Cellular Localization
Ubiquitin Protein Ligase Activity
Mon1-Ccz1 Complex
Vacuolar Transport
Organelle Transport Along Microtubule
Protein Modification By Small Protein Conjugation
Cytoplasm
Vesicle-mediated Transport In Synapse
Melanosome Organization
Vesicle
Endosome Membrane
Post-Golgi Vesicle-mediated Transport
Pigment Granule Organization
Modification-dependent Protein Catabolic Process
Ubiquitin Binding
Protein Localization To Ciliary Membrane
Regulation Of Lysosome Size
BORC Complex
Cytoskeleton-dependent Intracellular Transport
Early Endosome Membrane
Microvesicle
Protein Targeting
Early Endosome
Endosome To Melanosome Transport
Fat Pad Development
Regulation Of Endosome Size
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Cytosol
Post-translational Protein Modification
Vesicle-mediated Transport To The Plasma Membrane
Cytoplasmic Side Of Lysosomal Membrane
Proteolysis Involved In Protein Catabolic Process
Golgi To Plasma Membrane Transport
Intracellular Protein Transport
Secretion By Cell
Regulation Of SNARE Complex Assembly
Endosomal Vesicle Fusion
HOPS Complex
CORVET Complex
Endosome To Lysosome Transport
Clathrin-coated Vesicle
Vesicle Fusion
Organelle Membrane Fusion
Early Endosome
Lysosomal Transport
Organelle Fusion
Late Endosome Membrane
Late Endosome
Membrane Fusion
Vacuolar Transport
AP-3 Adaptor Complex
Endosome
Endosome Membrane
Autophagosome
Autophagy
Vesicle Organization
Lysosomal Membrane
Regulation Of Protein-containing Complex Assembly
Protein Transport
Vesicle-mediated Transport
Lysosome
Intracellular Transport
Establishment Of Protein Localization
Intracellular Protein Transport
Membrane Organization
Cellular Localization
Establishment Of Localization In Cell
Vesicle Tethering Complex
Intracellular Protein Localization
Cytoplasmic Vesicle
Clathrin Complex
Organelle Localization
Regulation Of Cellular Component Organization
Negative Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Vacuole Organization
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Vesicle Docking Involved In Exocytosis
Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Catabolic Process
Syntaxin Binding
Autophagosome Maturation
Lysosome Localization
Ubiquitin Protein Ligase Activity
Vesicle Docking
Endocytic Vesicle
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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