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GPRASP2 and CHRM1
Number of citations of the paper that reports this interaction (PMID
15086532
)
18
Data Source:
HPRD
(in vitro)
GPRASP2
CHRM1
Gene Name
G protein-coupled receptor associated sorting protein 2
cholinergic receptor, muscarinic 1
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Plasma Membrane
Integral Component Of Plasma Membrane
Postsynaptic Density
Membrane
Cell Junction
Dendrite
Asymmetric Synapse
Axon Terminus
Postsynaptic Membrane
Molecular Function
Beta-amyloid Binding
Phosphatidylinositol Phospholipase C Activity
Drug Binding
G-protein Coupled Acetylcholine Receptor Activity
Biological Process
Cellular Protein Modification Process
Signal Transduction
G-protein Coupled Receptor Signaling Pathway
Protein Kinase C-activating G-protein Coupled Receptor Signaling Pathway
Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Neuromuscular Synaptic Transmission
Nervous System Development
Cell Proliferation
Positive Regulation Of Cell Proliferation
Regulation Of Locomotion
Positive Regulation Of Ion Transport
Saliva Secretion
Cognition
Positive Regulation Of Intracellular Protein Transport
Pathways
G alpha (q) signalling events
G alpha (q) signalling events
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
Signaling by GPCR
GPCR downstream signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Class A/1 (Rhodopsin-like receptors)
Muscarinic acetylcholine receptors
Amine ligand-binding receptors
Metabolic disorders of biological oxidation enzymes
GPCR ligand binding
Drugs
Cevimeline
Succinylcholine
Trospium
Citalopram
Oxyphenonium
Benzatropine
Ziprasidone
Disopyramide
Amitriptyline
Ipratropium bromide
Olanzapine
Metixene
Buclizine
Clozapine
Doxylamine
Trihexyphenidyl
Oxyphencyclimine
Procyclidine
Ethopropazine
Carbachol
Promazine
Hyoscyamine
Cyproheptadine
Imipramine
Methylscopolamine
Darifenacin
Tridihexethyl
Triflupromazine
Anisotropine Methylbromide
Nortriptyline
Amoxapine
Atropine
Nicardipine
Pirenzepine
Paroxetine
Homatropine Methylbromide
Scopolamine
Benzquinamide
Clidinium
Propiomazine
Propantheline
Cryptenamine
Dicyclomine
Minaprine
Tropicamide
Biperiden
Brompheniramine
Flupenthixol
Cocaine
Maprotiline
Methantheline
Cycrimine
Cyclopentolate
Glycopyrrolate
Tolterodine
Oxybutynin
Promethazine
Pilocarpine
Doxepin
Flavoxate
Desipramine
Escitalopram
Quetiapine
Diphenidol
Metoclopramide
Aripiprazole
Chlorprothixene
Methotrimeprazine
Tiotropium
Solifenacin
Molindone
Arecoline
Mepenzolate
Fesoterodine
Aclidinium
Diseases
GWAS
Protein-Protein Interactions
25 interactors:
ADRB1
ARHGEF6
BARD1
BZRAP1
C6orf165
CALCR
CBX8
CHRM1
CHRM2
DISC1
FRAT1
HAP1
HRH2
HTR7
HTT
KIAA1377
LOC149950
LRIF1
MYOT
PTN
RPS6KA5
STMN2
TCF25
TXN
TXN2
4 interactors:
CDC14A
GNAI2
GPRASP1
GPRASP2
Entrez ID
114928
1128
HPRD ID
06612
00338
Ensembl ID
ENSG00000158301
ENSG00000168539
Uniprot IDs
B3KW05
Q96D09
P11229
Q53XZ3
PDB IDs
Enriched GO Terms of Interacting Partners
?
G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Cell Surface Receptor Signaling Pathway
Cell-cell Signaling
Homeostatic Process
Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Phospholipase C-activating G-protein Coupled Acetylcholine Receptor Signaling Pathway
Positive Regulation Of Cation Channel Activity
Cell Communication
Cellular Response To Stimulus
Cognition
Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity
Synaptic Transmission
Positive Regulation Of Ion Transmembrane Transporter Activity
Negative Regulation Of Protein Export From Nucleus
Positive Regulation Of Transporter Activity
Signaling
Positive Regulation Of Ion Transport
Cellular Homeostasis
Regulation Of Blood Vessel Size
Regulation Of Tube Size
Positive Regulation Of Ion Transmembrane Transport
Regulation Of Cation Channel Activity
Signal Transduction
G-protein Coupled Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Learning Or Memory
Response To Stimulus
Glycerol Ether Metabolic Process
Cell Redox Homeostasis
Memory
Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway
Regulation Of Cellular Process
Positive Regulation Of Calcium Ion Transmembrane Transporter Activity
Secretion
Learning
Regulation Of Ion Transmembrane Transporter Activity
Regulation Of Transmembrane Transporter Activity
Regulation Of Protein Export From Nucleus
Vasoconstriction
Developmental Process
Vesicle Transport Along Microtubule
Positive Regulation Of Adenylate Cyclase Activity
Anatomical Structure Development
Regulation Of Intracellular Transport
Positive Regulation Of Receptor Activity
Regulation Of Calcium Ion Transport
Single-organism Behavior
Response To Reactive Oxygen Species
Nervous System Development
Positive Regulation Of Signal Transduction
G-protein Coupled Receptor Catabolic Process
Cell Division
Adenosine Receptor Signaling Pathway
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Receptor Catabolic Process
Negative Regulation Of Adenylate Cyclase Activity
Cell Proliferation
Negative Regulation Of Lyase Activity
Negative Regulation Of CAMP Biosynthetic Process
Endosome To Lysosome Transport
Gamma-aminobutyric Acid Signaling Pathway
Negative Regulation Of CAMP Metabolic Process
Negative Regulation Of Nucleotide Metabolic Process
Lysosomal Transport
Regulation Of Adenylate Cyclase Activity
Negative Regulation Of Signaling
Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission
Regulation Of Cyclase Activity
Activation Of MAPKK Activity
Cell Cycle
Vacuolar Transport
Receptor Metabolic Process
Regulation Of CAMP Biosynthetic Process
Tagcloud
?
acetylcholine
adaptor
alanine
ap
canonical
cholinergic
clathrin
constitutive
depended
dynamin
governed
i445a
interacted
internalization
investigations
lost
machr
motif
mu2
muscarinic
n1e
neuroblastoma
resembles
tryptophan
w442a
w442y
wxxi
yxxphi
Tagcloud (Difference)
?
acetylcholine
adaptor
alanine
ap
canonical
cholinergic
clathrin
constitutive
depended
dynamin
governed
i445a
interacted
internalization
investigations
lost
machr
motif
mu2
muscarinic
n1e
neuroblastoma
resembles
tryptophan
w442a
w442y
wxxi
yxxphi
Tagcloud (Intersection)
?