GPRASP2 and HRH2

Number of citations of the paper that reports this interaction (PubMedID 15086532)
0

Data Source:
HPRD (in vitro)

		GPRASP2	HRH2
Description		G protein-coupled receptor associated sorting protein 2	histamine receptor H2
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Plasma Membrane Membrane Dendrite Synapse
	Molecular Function	Amyloid-beta Binding G Protein-coupled Receptor Binding Protein Binding	G Protein-coupled Receptor Activity Histamine Receptor Activity Neurotransmitter Receptor Activity
	Biological Process	Hematopoietic Stem Cell Homeostasis	Gastric Acid Secretion Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Positive Regulation Of Vasoconstriction
Pathways			Histamine receptors G alpha (s) signalling events
Drugs			Betazole Amitriptyline Loxapine Cyproheptadine Cimetidine Nizatidine Epinastine Olopatadine Tolazoline Ranitidine Famotidine Methantheline Azelastine Promethazine Doxepin Aripiprazole HZT-501 Histamine Asenapine Metiamide Roxatidine acetate Viloxazine Niperotidine
Diseases
GWAS			Anti-thyroid peroxidase (TPOAb) levels in Hashimoto's thyroiditis ( 30926877) Mosquito bite size ( 28199695) Night sleep phenotypes ( 27126917)
Interacting Genes		52 interacting genes: ADRB1 ARHGEF6 BARD1 CALCR CAVIN3 CBX8 CCDC146 CEP126 CFAP206 CHRM1 CHRM2 DISC1 DSCR9 EFCAB3 FAM124B FCHSD2 FOXD4L1 FRAT1 GADD45GIP1 HAP1 HRH2 HTR7 HTT LRIF1 MBD3L2 MICU2 MYOT NOL4L-DT PIH1D2 PLAC9 PRPF3 PTN RABGEF1 REX1BD RHPN1 RNF8 RPS6KA5 SAPCD2 SEZ6L SH2D4A SREK1 STMN2 TBRG4 TCF25 TSPOAP1 TTC23 TXN TXN2 USP20 ZC2HC1C ZFYVE26 ZNF688	1 interacting genes: GPRASP2
Entrez ID		114928	3274
HPRD ID		06612	00816
Ensembl ID		ENSG00000158301	ENSG00000113749
Uniprot IDs		B3KW05 Q96D09	A0A1B0GTK7 P25021
PDB IDs			7UL3 8POK 8YN3 8YN4 8YUT
Enriched GO Terms of Interacting Partners?		G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Chemical Synaptic Transmission Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Trans-synaptic Signaling G Protein-coupled Acetylcholine Receptor Activity Synaptic Signaling Neuromuscular Synaptic Transmission Regulation Of Protein Export From Nucleus Negative Regulation Of Protein Export From Nucleus Adenylate Cyclase-inhibiting G Protein-coupled Acetylcholine Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Microtubule Cytoskeleton Organization Cholinergic Synapse Dendrite	Axon Extension Involved In Axon Guidance Response To Cortisol Chemorepulsion Involved In Embryonic Olfactory Bulb Interneuron Precursor Migration Apoptotic Process Involved In Luteolysis Negative Regulation Of Chemokine-mediated Signaling Pathway Roundabout Binding Roundabout Signaling Pathway Atrioventricular Valve Morphogenesis Hematopoietic Stem Cell Homeostasis Apoptotic Process Involved In Development Aortic Valve Morphogenesis Ventricular Septum Morphogenesis Negative Chemotaxis Axon Extension Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Heart Valve Morphogenesis Cardiac Septum Morphogenesis G Protein-coupled Receptor Binding
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