VASP and LPP

Number of citations of the paper that reports this interaction (PMID 10637295)
38

Data Source:
HPRD (in vivo, in vitro)

		VASP	LPP
Gene Name		vasodilator-stimulated phosphoprotein	LIM domain containing preferred translocation partner in lipoma
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Vesicular Exosome	Nucleus Cytoplasm Plasma Membrane Focal Adhesion
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding Zinc Ion Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly T Cell Receptor Signaling Pathway Protein Homotetramerization	Cell Adhesion Biological_process
Pathways		Cell junction organization TCR signaling Generation of second messenger molecules Axon guidance Signaling by Robo receptor Cell-extracellular matrix interactions Adaptive Immune System
Drugs
Diseases
GWAS			B cell non-Hodgkin lymphoma ( 23749188) Celiac disease ( 20190752 18311140) IgE levels ( 22075330) Immune reponse to smallpox (secreted IFN-alpha) ( 22610502) Obesity-related traits ( 23251661) Renal function-related traits (BUN) ( 22797727) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Vitiligo ( 22951725 20410501) White matter integrity (interaction) ( 23218918)
Protein-Protein Interactions		36 interactors: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP DMRTB1 DNMBP ERMAP FAT1 FGFR1OP FYB GSN LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	6 interactors: ACTN1 ATP5J2 ATRAID SCRIB SHPRH VASP
Entrez ID		7408	4026
HPRD ID		03415	02828
Ensembl ID		ENSG00000125753	ENSG00000145012
Uniprot IDs		P50552	B7Z8W0 B7ZLW0 Q93052
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Actin Filament Organization Movement Of Cell Or Subcellular Component Response To Wounding Organelle Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Polymerization Or Depolymerization Blood Coagulation Positive Regulation Of Actin Nucleation Wound Healing Hemostasis Platelet Activation Positive Regulation Of Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Development Locomotion Negative Regulation Of Protein Complex Assembly Regulation Of Body Fluid Levels Regulation Of Actin Filament-based Process Negative Regulation Of Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cell Projection Organization Regulation Of Actin Nucleation Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Regulation Of Cellular Process Positive Regulation Of ATPase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Neuron Projection Development Actomyosin Structure Organization Cell Projection Morphogenesis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Regulation Of ATPase Activity Positive Regulation Of Immune System Process Regulation Of Organelle Organization Anatomical Structure Development Fc Receptor Signaling Pathway Cell Activation Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Development Regulation Of Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Component Biogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Protein Localization To Cell Junction Neural Tube Closure Neural Tube Formation Embryonic Epithelial Tube Formation Epithelial Tube Formation Negative Regulation Of Cyclin Catabolic Process Tube Formation Morphogenesis Of Embryonic Epithelium Protein Localization To Tight Junction Cochlear Nucleus Development Protein Localization To Adherens Junction Neural Tube Development Cell Junction Assembly Establishment Of Apical/basal Cell Polarity Synaptic Vesicle Targeting Astrocyte Cell Migration Actin Filament Organization Auditory Receptor Cell Stereocilium Organization Establishment Of Monopolar Cell Polarity Exocytosis Pons Development Negative Regulation Of Osteoblast Proliferation Auditory Receptor Cell Morphogenesis Activation Of Rac GTPase Activity Epithelial Tube Morphogenesis Mitochondrial ATP Synthesis Coupled Proton Transport Auditory Receptor Cell Development Actin Crosslink Formation Positive Regulation Of Receptor Recycling Tube Morphogenesis Inner Ear Receptor Stereocilium Organization
Tagcloud ?		abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin	arousal behavioural correlation degree denenberg describes direction documented exhibit lateral lateralities medial mpp paw periods preference preferences regardless relations rodents seemingly side sp spatial states strength strong terms waters
Tagcloud (Difference) ?		abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin	arousal behavioural correlation degree denenberg describes direction documented exhibit lateral lateralities medial mpp paw periods preference preferences regardless relations rodents seemingly side sp spatial states strength strong terms waters
Tagcloud (Intersection) ?