VASP and NOL3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VASP	NOL3
Gene Name		vasodilator-stimulated phosphoprotein	nucleolar protein 3 (apoptosis repressor with CARD domain)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Vesicular Exosome	Nucleolus Cytoplasm Mitochondrion Cytosol Sarcoplasm
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	RNA Binding Protein Binding Identical Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process Caspase Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly T Cell Receptor Signaling Pathway Protein Homotetramerization	Response To Hypoxia MRNA Splice Site Selection RNA Splicing Response To Injury Involved In Regulation Of Muscle Adaptation Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Oligomerization Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Cell junction organization TCR signaling Generation of second messenger molecules Axon guidance Signaling by Robo receptor Cell-extracellular matrix interactions Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP DMRTB1 DNMBP ERMAP FAT1 FGFR1OP FYB GSN LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	15 interactors: BAX CASP2 CASP8 CSNK2A1 ETNK2 FADD NIF3L1 POT1 SIRPA SRSF9 TERF1 TERF2IP TFPT TINF2 VASP
Entrez ID		7408	8996
HPRD ID		03415	05572
Ensembl ID		ENSG00000125753	ENSG00000140939
Uniprot IDs		P50552	B4DFL0 O60936 Q5TZN6
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Actin Filament Organization Movement Of Cell Or Subcellular Component Response To Wounding Organelle Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Polymerization Or Depolymerization Blood Coagulation Positive Regulation Of Actin Nucleation Wound Healing Hemostasis Platelet Activation Positive Regulation Of Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Development Locomotion Negative Regulation Of Protein Complex Assembly Regulation Of Body Fluid Levels Regulation Of Actin Filament-based Process Negative Regulation Of Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cell Projection Organization Regulation Of Actin Nucleation Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Regulation Of Cellular Process Positive Regulation Of ATPase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Neuron Projection Development Actomyosin Structure Organization Cell Projection Morphogenesis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Regulation Of ATPase Activity Positive Regulation Of Immune System Process Regulation Of Organelle Organization Anatomical Structure Development Fc Receptor Signaling Pathway Cell Activation Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Development Regulation Of Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Component Biogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Negative Regulation Of Chromosome Organization Negative Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Via Telomere Lengthening Regulation Of Organelle Organization Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Positive Regulation Of Organelle Organization Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Regulation Of Chromosome Organization Regulation Of Cysteine-type Endopeptidase Activity RNA-dependent DNA Replication Negative Regulation Of DNA Metabolic Process Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death TRAIL-activated Apoptotic Signaling Pathway Positive Regulation Of Cell Death Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Regulation Of Proteolysis Regulation Of Endopeptidase Activity Negative Regulation Of DNA Replication Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Peptidase Activity Protein Oligomerization Protein Localization To Chromosome, Telomeric Region Telomere Capping Positive Regulation Of Apoptotic Signaling Pathway Cellular Component Assembly Telomere Assembly Regulation Of Lymphocyte Apoptotic Process Regulation Of Cellular Component Organization Protein Processing Cellular Response To Mechanical Stimulus Regulation Of Apoptotic Process Apoptotic Process Negative Regulation Of Telomerase Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cell Death Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Telomere Maintenance Programmed Cell Death Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Macrophage Differentiation Cell Death Activation Of Cysteine-type Endopeptidase Activity Death
Tagcloud ?		abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin	bak1 birc2 birc3 c57bl cgy eosin evident gamma greatest gy hematoxylin irradiated ldr livers mcl1 modified nearly phagocytosis proton protons radiation radical ray rays regimen sections stained strikingly traf3
Tagcloud (Difference) ?		abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin	bak1 birc2 birc3 c57bl cgy eosin evident gamma greatest gy hematoxylin irradiated ldr livers mcl1 modified nearly phagocytosis proton protons radiation radical ray rays regimen sections stained strikingly traf3
Tagcloud (Intersection) ?