VASP and DNMBP

Number of citations of the paper that reports this interaction (PubMedID 14506234)
0

Data Source:
BioGRID (pull down, proximity labelling technology)

		VASP	DNMBP
Description		vasodilator stimulated phosphoprotein	dynamin binding protein
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Bicellular Tight Junction Focal Adhesion Actin Cytoskeleton Membrane Lamellipodium Filopodium Lamellipodium Membrane Filopodium Membrane Cell Projection Extracellular Exosome Anchoring Junction Postsynapse Glutamatergic Synapse	Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Golgi Stack Cytosol Cytoskeleton Cell-cell Junction Nuclear Body Synapse Anchoring Junction Presynapse
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding Cadherin Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Protein Homotetramerization	Regulation Of Cell Shape Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Cilium Assembly
Pathways		Generation of second messenger molecules Signaling by ROBO receptors Signaling by ROBO receptors Cell-extracellular matrix interactions	CDC42 GTPase cycle
Drugs
Diseases
GWAS		Alzheimer's disease or HDL levels (pleiotropy) ( 30805717)	Stent thrombosis in response to clopidogrel treatment ( 32472697)
Interacting Genes		49 interacting genes: ABI1 ABI2 ABI3 ACTA1 ACTG1 AEBP1 APBB1 APBB1IP CDC42 CEBPA DMRTB1 DNMBP ENAH ERMAP FAF2 FAT1 FRS3 FYB1 GSN IQGAP1 LPP MAGED1 MRPL43 NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A PSORS1C2 RAD51 RAPH1 SAT1 SCGB2A2 SHROOM3 SPTA1 TES TRIM15 TRIM9 VCL WAS WASL WWP2 XIRP1 XIRP2 XPO6 ZYX	21 interacting genes: ACTA1 ARHGAP17 BUB1B CDC42 CNN1 CYFIP2 DBN1 DNM1 ENAH EVL FASLG HSPA1B KHDRBS1 NCKAP1 RAC1 RAPH1 UBC VASP WASF1 WASL WIPF2
Entrez ID		7408	23268
HPRD ID		03415	10918
Ensembl ID		ENSG00000125753	ENSG00000107554
Uniprot IDs		A0A024R0V4 P50552	A0A1B0GTX1 A0A1C7CYY6 B3KY33 Q6XZF7
PDB IDs		1EGX 1USD 1USE 2PAV 2PBD 3CHW 8GAT 8GAU	1UG1 1UHC 4CC2 4CC3 4CC4 4CC7 4GLM
Enriched GO Terms of Interacting Partners?		Actin Filament Organization Focal Adhesion Lamellipodium Supramolecular Fiber Organization Actin Filament-based Process Anchoring Junction Actin Cytoskeleton Organization Cytoskeleton Filopodium Actin Cytoskeleton Cytoplasm Actin Binding Actin Polymerization Or Depolymerization Regulation Of Actin Filament Organization Cytoskeleton Organization Cell-cell Junction Regulation Of Actin Cytoskeleton Organization Cytosol Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Actin-based Cell Projection Actin Filament Binding Cellular Response To Type II Interferon SCAR Complex Phagocytic Vesicle Regulation Of Cell Projection Assembly Regulation Of Lamellipodium Assembly Actin Filament Stress Fiber Modification Of Postsynaptic Actin Cytoskeleton Regulation Of Stress Fiber Assembly Organelle Organization Response To Type II Interferon Cell Projection Morphogenesis Regulation Of Lamellipodium Organization Regulation Of Cytoskeleton Organization Adherens Junction SH3 Domain Binding Cortical Actin Cytoskeleton Modification Of Postsynaptic Structure Negative Regulation Of Cellular Component Organization Cell Leading Edge Modification Of Synaptic Structure Cell Projection Organization Cell Junction Organization Actin Cap Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Ruffle Assembly Actin Filament Polymerization	Actin Filament Organization Lamellipodium Cytoskeleton Actin Polymerization Or Depolymerization Supramolecular Fiber Organization Profilin Binding Focal Adhesion Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Actin Binding Regulation Of Actin Filament-based Process Regulation Of Supramolecular Fiber Organization Regulation Of Actin Filament Organization Filopodium Neuron Projection Development Positive Regulation Of Protein Polymerization Actin Cytoskeleton Organization SH3 Domain Binding Positive Regulation Of Cellular Component Organization Postsynapse SCAR Complex Positive Regulation Of Actin Filament Polymerization Regulation Of Actin Filament Polymerization Actin Filament-based Process Plasma Membrane Bounded Cell Projection Organization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein-containing Complex Assembly Regulation Of Postsynapse Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Cellular Component Organization Regulation Of Actin Filament Length Actin Cytoskeleton Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Component Biogenesis Cell Projection Organization Cytoplasm Rac Protein Signal Transduction Positive Regulation Of Protein-containing Complex Assembly Cytosol Positive Regulation Of Lamellipodium Assembly Axon Guidance Neuron Projection Guidance Cell Projection Regulation Of Cell Projection Assembly Actin Filament Polymerization Extracellular Exosome Positive Regulation Of Lamellipodium Organization
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