VASP and XPO6

Number of citations of the paper that reports this interaction (PMID 14592989)
52

Data Source:
HPRD (in vitro)

		VASP	XPO6
Gene Name		vasodilator-stimulated phosphoprotein	exportin 6
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Tight Junction Focal Adhesion Actin Cytoskeleton Lamellipodium Membrane Filopodium Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane
	Molecular Function	Actin Binding Protein Binding Profilin Binding SH3 Domain Binding	Protein Binding Ran GTPase Binding Protein Transporter Activity
	Biological Process	Neural Tube Closure Axon Guidance Actin Polymerization Or Depolymerization Positive Regulation Of Actin Filament Polymerization Cell Junction Assembly T Cell Receptor Signaling Pathway Protein Homotetramerization	Protein Export From Nucleus
Pathways		Cell junction organization TCR signaling Generation of second messenger molecules Axon guidance Signaling by Robo receptor Cell-extracellular matrix interactions Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ABI1 ABI2 ABI3 ACTA1 ACTG1 APBB1 APBB1IP DMRTB1 DNMBP ERMAP FAT1 FGFR1OP FYB GSN LPP NOL3 NR4A1 PFN1 PFN2 PLSCR1 PRKACA PRKG1 PRPF40A RAPH1 SAT1 SCGB2A2 SPTA1 TES TRIM9 VCL WAS WASL WWP2 XIRP1 XPO6 ZYX	5 interactors: ACTB DIAPH1 NUP62 PFN1 VASP
Entrez ID		7408	23214
HPRD ID		03415	10525
Ensembl ID		ENSG00000125753	ENSG00000169180
Uniprot IDs		P50552	B3KW08 D3DWF9 Q96QU8
PDB IDs		1EGX 1JNG 1USD 1USE 2PAV 2PBD 3CHW
Enriched GO Terms of Interacting Partners?		Actin Cytoskeleton Organization Actin Filament-based Process Cytoskeleton Organization Actin Filament Organization Movement Of Cell Or Subcellular Component Response To Wounding Organelle Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Polymerization Or Depolymerization Blood Coagulation Positive Regulation Of Actin Nucleation Wound Healing Hemostasis Platelet Activation Positive Regulation Of Cytoskeleton Organization Anatomical Structure Morphogenesis Regulation Of Actin Cytoskeleton Organization Cell Development Locomotion Negative Regulation Of Protein Complex Assembly Regulation Of Body Fluid Levels Regulation Of Actin Filament-based Process Negative Regulation Of Actin Filament Polymerization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Cell Projection Organization Regulation Of Actin Nucleation Regulation Of Cytoskeleton Organization Negative Regulation Of Protein Polymerization Regulation Of Cellular Component Organization Regulation Of Cellular Process Positive Regulation Of ATPase Activity Immune Response-regulating Cell Surface Receptor Signaling Pathway Neuron Projection Development Actomyosin Structure Organization Cell Projection Morphogenesis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Regulation Of ATPase Activity Positive Regulation Of Immune System Process Regulation Of Organelle Organization Anatomical Structure Development Fc Receptor Signaling Pathway Cell Activation Immune Response-regulating Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Neuron Development Regulation Of Immune System Process Regulation Of Catalytic Activity Positive Regulation Of Cellular Component Biogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis	Organelle Organization Actin Polymerization Or Depolymerization Actin Cytoskeleton Organization Actin Filament-based Process Neural Tube Closure Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Protein Polymerization Neural Tube Formation Embryonic Epithelial Tube Formation Epithelial Tube Formation Neuron Projection Development Nervous System Development Tube Formation Positive Regulation Of Protein Complex Assembly Morphogenesis Of Embryonic Epithelium Regulation Of Actin Filament Polymerization Neuron Development Platelet Activation Neural Tube Development Developmental Process Cell Junction Assembly Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Cytoskeleton Organization Cytoskeleton Organization Neuron Differentiation Cell Projection Organization Positive Regulation Of Ruffle Assembly Immune Response-activating Cell Surface Receptor Signaling Pathway Protein Localization To Microtubule Actin Filament Organization Positive Regulation Of Cellular Component Biogenesis Cellular Response To Stimulus Regulation Of Cellular Component Size Positive Regulation Of Cell Migration Cellular Response To Histamine Regulation Of Protein Complex Assembly Positive Regulation Of Cell Motility Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Stress Fiber Assembly Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Histamine Epithelial Tube Morphogenesis Generation Of Neurons Axon Guidance Negative Regulation Of Actin Filament Bundle Assembly Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process
Tagcloud ?		abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin
Tagcloud (Difference) ?		abm acta cardinal colocalize concentrates concentrating factories fppppx gppppp immunolocalization listeria microinjection motile motility perinuclear phosphoprotein profilin rear redistributed rocket shigella tails underscore vaccinia vasodilator vinculin virions xppppp zyxin
Tagcloud (Intersection) ?