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TOE1 and AP2A1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
TOE1
AP2A1
Gene Name
target of EGR1, member 1 (nuclear)
adaptor-related protein complex 2, alpha 1 subunit
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nuclear Speck
Cytosol
Plasma Membrane
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
AP-2 Adaptor Complex
Clathrin Coat Of Trans-Golgi Network Vesicle
Endocytic Vesicle Membrane
Clathrin-coated Endocytic Vesicle Membrane
Molecular Function
Nucleic Acid Binding
Protein Binding
Metal Ion Binding
Protein Binding
Protein C-terminus Binding
Protein Transporter Activity
Protein Kinase Binding
Clathrin Adaptor Activity
Biological Process
Intracellular Protein Transport
Golgi To Endosome Transport
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
Synaptic Transmission
Axon Guidance
Viral Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Regulation Of Defense Response To Virus By Virus
Clathrin-mediated Endocytosis
Negative Regulation Of Hyaluronan Biosynthetic Process
Pathways
Trafficking of GluR2-containing AMPA receptors
Retrograde neurotrophin signalling
Axon guidance
HIV Infection
Nef Mediated CD8 Down-regulation
L1CAM interactions
Signaling by Wnt
Signaling by EGFRvIII in Cancer
Recycling pathway of L1
EPH-ephrin mediated repulsion of cells
MHC class II antigen presentation
EPH-Ephrin signaling
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Nef Mediated CD4 Down-regulation
EGFR downregulation
Signalling by NGF
Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
Host Interactions of HIV factors
Signaling by Ligand-Responsive EGFR Variants in Cancer
The role of Nef in HIV-1 replication and disease pathogenesis
NGF signalling via TRKA from the plasma membrane
Signaling by Overexpressed Wild-Type EGFR in Cancer
Trafficking of AMPA receptors
beta-catenin independent WNT signaling
Signaling by EGFR
WNT5A-dependent internalization of FZD4
Signaling by EGFR in Cancer
Glutamate Binding, Activation of AMPA Receptors and Synaptic Plasticity
PCP/CE pathway
Adaptive Immune System
Transmission across Chemical Synapses
Drugs
Diseases
GWAS
Protein-Protein Interactions
25 interactors:
ABCF3
AGGF1
AP2A1
APLP1
CA12
HNRNPF
IK
IL7R
LSM4
PPP1CA
PRCC
RAB40C
RBM39
RBM8A
RPS3A
SF3B2
SF3B3
SH3GL3
SQSTM1
SRSF6
SUMO1
U2AF1
UNC13B
WDR77
WDR83
27 interactors:
AMPH
AP2S1
BIN1
CLINT1
DEK
DNM2
DPYSL2
EHD1
EPN1
EPS15
GHR
HIP1
MYO6
NAGPA
NUMB
PICALM
PIN1
RAB11FIP2
RIT1
SHBG
SHC1
SMAD9
SNAP29
SYNJ1
SYT3
SYT7
TOE1
Entrez ID
114034
160
HPRD ID
18212
03016
Ensembl ID
ENSG00000132773
ENSG00000196961
Uniprot IDs
B4DEM6
Q96GM8
O95782
PDB IDs
2FC6
Enriched GO Terms of Interacting Partners
?
MRNA Metabolic Process
RNA Processing
MRNA Processing
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA 3'-end Processing
RNA 3'-end Processing
RNA Metabolic Process
Termination Of RNA Polymerase II Transcription
Gene Expression
Nucleobase-containing Compound Metabolic Process
MRNA Export From Nucleus
DNA-templated Transcription, Termination
RNA Export From Nucleus
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Nuclear Export
MRNA Transport
Nitrogen Compound Metabolic Process
RNA Transport
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Cellular Localization
Nuclear-transcribed MRNA Catabolic Process
RNA Localization
MRNA Catabolic Process
Cytoplasmic Transport
Establishment Of Localization In Cell
Intracellular Transport
RNA Catabolic Process
Positive Regulation Of Synaptic Vesicle Priming
Positive Regulation Of Synaptic Vesicle Exocytosis
Interleukin-7-mediated Signaling Pathway
Regulation Of MRNA Splicing, Via Spliceosome
Nucleocytoplasmic Transport
Cellular Metabolic Process
Nuclear Transport
Negative Regulation Of Hyaluronan Biosynthetic Process
Cellular Response To Norepinephrine Stimulus
Regulation Of Epithelial Cell Proliferation
Regulation Of MRNA Processing
PML Body Organization
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Negative Regulation Of T Cell Mediated Cytotoxicity
Cellular Process
Vesicle-mediated Transport
Endocytosis
Clathrin Coat Assembly
Establishment Of Localization In Cell
Synaptic Vesicle Transport
Cellular Localization
Regulation Of Vesicle-mediated Transport
Membrane Budding
Transport
Cellular Protein Complex Assembly
Establishment Of Vesicle Localization
Vesicle Organization
Vesicle Localization
Synaptic Transmission
Signaling
Membrane Organization
Cell Communication
Cellular Macromolecular Complex Assembly
Cell-cell Signaling
Establishment Of Organelle Localization
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuron Projection Development
Regulation Of Endocytosis
Regulation Of ERBB Signaling Pathway
Regulation Of Cellular Component Organization
Organelle Localization
Neuron Development
Synaptic Vesicle Endocytosis
Synaptic Vesicle Recycling
Protein Complex Assembly
Positive Regulation Of Transport
Secretion By Cell
Cellular Component Assembly
Receptor Internalization
Neuron Differentiation
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Cell Projection Organization
Negative Regulation Of ERBB Signaling Pathway
Generation Of Neurons
Exocytosis
Epidermal Growth Factor Receptor Signaling Pathway
Synaptic Vesicle Priming
ERBB Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Neurogenesis
Secretion
Neuron Projection Morphogenesis
Response To Stimulus
Cellular Response To Stimulus
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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