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TOE1 and SRSF6
Number of citations of the paper that reports this interaction (PMID
22365833
)
24
Data Source:
BioGRID
(two hybrid)
TOE1
SRSF6
Gene Name
target of EGR1, member 1 (nuclear)
serine/arginine-rich splicing factor 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nuclear Speck
Nucleoplasm
Nuclear Speck
Molecular Function
Nucleic Acid Binding
Protein Binding
Metal Ion Binding
Nucleotide Binding
RNA Binding
Pre-mRNA Binding
Poly(A) RNA Binding
Biological Process
Alternative MRNA Splicing, Via Spliceosome
Regulation Of Alternative MRNA Splicing, Via Spliceosome
MRNA Splicing, Via Spliceosome
Transcription From RNA Polymerase II Promoter
Termination Of RNA Polymerase II Transcription
MRNA Splice Site Selection
MRNA Export From Nucleus
RNA Splicing
Gene Expression
Regulation Of Keratinocyte Proliferation
MRNA 3'-end Processing
Negative Regulation Of Keratinocyte Differentiation
Negative Regulation Of MRNA Splicing, Via Spliceosome
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Negative Regulation Of Cell Death
Regulation Of Wound Healing
Pathways
mRNA Splicing
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Transcription
Transport of Mature mRNA derived from an Intron-Containing Transcript
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Transport of Mature Transcript to Cytoplasm
Cleavage of Growing Transcript in the Termination Region
RNA Polymerase II Transcription Termination
mRNA 3'-end processing
Drugs
Diseases
GWAS
Protein-Protein Interactions
25 interactors:
ABCF3
AGGF1
AP2A1
APLP1
CA12
HNRNPF
IK
IL7R
LSM4
PPP1CA
PRCC
RAB40C
RBM39
RBM8A
RPS3A
SF3B2
SF3B3
SH3GL3
SQSTM1
SRSF6
SUMO1
U2AF1
UNC13B
WDR77
WDR83
14 interactors:
APP
CLK1
LUC7L2
PPARGC1A
RBM10
RNPS1
SF3B4
SREK1
SRPK1
SRSF4
TERF1
TERF2
TOE1
TRA2B
Entrez ID
114034
6431
HPRD ID
18212
09054
Ensembl ID
ENSG00000132773
ENSG00000124193
Uniprot IDs
B4DEM6
Q96GM8
Q13247
PDB IDs
2FC6
Enriched GO Terms of Interacting Partners
?
MRNA Metabolic Process
RNA Processing
MRNA Processing
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA 3'-end Processing
RNA 3'-end Processing
RNA Metabolic Process
Termination Of RNA Polymerase II Transcription
Gene Expression
Nucleobase-containing Compound Metabolic Process
MRNA Export From Nucleus
DNA-templated Transcription, Termination
RNA Export From Nucleus
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Nuclear Export
MRNA Transport
Nitrogen Compound Metabolic Process
RNA Transport
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Cellular Localization
Nuclear-transcribed MRNA Catabolic Process
RNA Localization
MRNA Catabolic Process
Cytoplasmic Transport
Establishment Of Localization In Cell
Intracellular Transport
RNA Catabolic Process
Positive Regulation Of Synaptic Vesicle Priming
Positive Regulation Of Synaptic Vesicle Exocytosis
Interleukin-7-mediated Signaling Pathway
Regulation Of MRNA Splicing, Via Spliceosome
Nucleocytoplasmic Transport
Cellular Metabolic Process
Nuclear Transport
Negative Regulation Of Hyaluronan Biosynthetic Process
Cellular Response To Norepinephrine Stimulus
Regulation Of Epithelial Cell Proliferation
Regulation Of MRNA Processing
PML Body Organization
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Negative Regulation Of T Cell Mediated Cytotoxicity
Cellular Process
MRNA Processing
MRNA Metabolic Process
RNA Processing
RNA Splicing
Regulation Of RNA Splicing
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of MRNA Processing
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nitrogen Compound Metabolic Process
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
RNA Metabolic Process
Telomeric Loop Formation
Age-dependent Telomere Shortening
Gene Expression
Telomere Maintenance Via Telomere Shortening
Replicative Cell Aging
MRNA 3'-end Processing
Regulation Of Nuclear Cell Cycle DNA Replication
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Cellular Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
RNA 3'-end Processing
Negative Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Telomere Maintenance
Negative Regulation Of RNA Splicing
RNA-dependent DNA Replication
Positive Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of RNA Splicing
Regulation Of Chromosome Organization
Termination Of RNA Polymerase II Transcription
Negative Regulation Of DNA Replication
Negative Regulation Of Cellular Metabolic Process
Cellular Response To Nitrite
MRNA Export From Nucleus
DNA-templated Transcription, Termination
Cell Aging
RNA Export From Nucleus
Regulation Of RNA Metabolic Process
Telomere Maintenance
Metabolic Process
Regulation Of Metabolic Process
Negative Regulation Of Chromosome Organization
Tagcloud
?
a1
a1b
a2
anchorage
b1
constitutive
dominant
egf
elevating
erk
erk1
hcc
hepatocellular
hnrnp
immortalized
isoform
knockdown
mapk
mek
oncogenes
overexpressing
progenitor
raf
ras
regulates
splicing
srsf1
switch
transcript
Tagcloud (Difference)
?
a1
a1b
a2
anchorage
b1
constitutive
dominant
egf
elevating
erk
erk1
hcc
hepatocellular
hnrnp
immortalized
isoform
knockdown
mapk
mek
oncogenes
overexpressing
progenitor
raf
ras
regulates
splicing
srsf1
switch
transcript
Tagcloud (Intersection)
?