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TOE1 and PPP1CA
Number of citations of the paper that reports this interaction (PMID
22365833
)
24
Data Source:
BioGRID
(two hybrid)
TOE1
PPP1CA
Gene Name
target of EGR1, member 1 (nuclear)
protein phosphatase 1, catalytic subunit, alpha isozyme
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Nuclear Speck
Protein Phosphatase Type 1 Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Glycogen Granule
Dendritic Spine
Perikaryon
Extracellular Vesicular Exosome
MLL5-L Complex
PTW/PP1 Phosphatase Complex
Molecular Function
Nucleic Acid Binding
Protein Binding
Metal Ion Binding
Protein Serine/threonine Phosphatase Activity
Protein Binding
Phosphatase Activity
Ribonucleoprotein Complex Binding
Metal Ion Binding
Biological Process
Glycogen Metabolic Process
Regulation Of Glycogen Biosynthetic Process
Regulation Of Glycogen Catabolic Process
Protein Dephosphorylation
Cell Cycle
Transforming Growth Factor Beta Receptor Signaling Pathway
Triglyceride Catabolic Process
Lung Development
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Circadian Regulation Of Gene Expression
Regulation Of Circadian Rhythm
Entrainment Of Circadian Clock By Photoperiod
Small Molecule Metabolic Process
Branching Morphogenesis Of An Epithelial Tube
Cell Division
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Pathways
Loss of Function of TGFBR2 in Cancer
Signaling by GPCR
TGFBR2 MSI Frameshift Mutants in Cancer
Metabolism of lipids and lipoproteins
SMAD2/3 Phosphorylation Motif Mutants in Cancer
Loss of Function of SMAD2/3 in Cancer
Opioid Signalling
TGFBR2 Kinase Domain Mutants in Cancer
Loss of Function of SMAD4 in Cancer
Downregulation of TGF-beta receptor signaling
SMAD2/3 MH2 Domain Mutants in Cancer
TGFBR1 KD Mutants in Cancer
Lipid digestion, mobilization, and transport
TGF-beta receptor signaling activates SMADs
TGFBR1 LBD Mutants in Cancer
Loss of Function of TGFBR1 in Cancer
Signaling by TGF-beta Receptor Complex
Signaling by TGF-beta Receptor Complex in Cancer
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
DARPP-32 events
SMAD4 MH2 Domain Mutants in Cancer
Drugs
Diseases
GWAS
Protein-Protein Interactions
25 interactors:
ABCF3
AGGF1
AP2A1
APLP1
CA12
HNRNPF
IK
IL7R
LSM4
PPP1CA
PRCC
RAB40C
RBM39
RBM8A
RPS3A
SF3B2
SF3B3
SH3GL3
SQSTM1
SRSF6
SUMO1
U2AF1
UNC13B
WDR77
WDR83
148 interactors:
AATK
AKAP1
AKAP11
AKAP9
AKT1
APAF1
AURKA
BAD
BAX
BCL2
BCL2L1
BCL2L2
BRCA1
BTBD10
C1QA
CAD
CASC5
CAV1
CCDC181
CD2BP2
CDC5L
CDH1
CEP170
CKB
CLCN2
CLTC
CNP
CNST
CNTN1
CREB1
CRK
CSNK1E
CSRNP1
CSRNP2
CUL1
CXXC1
DCTN1
DCX
DEAF1
EED
EIF2AK2
FRMPD4
FXYD1
GLIPR1L2
GLTSCR2
GPKOW
H2AFX
HEYL
HSPA4
IBTK
ID2
JPH3
KANK1
KCNQ1
KCTD20
KIAA1377
KIF13A
KIF18A
LMTK2
LPIN2
MAFG
MAL2
MAP4K4
MAPK1
MAPK3
MIIP
MPHOSPH10
MST1R
MYO16
NCAM1
NDP
NEK2
NOC2L
NOM1
NONO
PCDH7
PCNA
PHACTR1
PHACTR3
PHACTR4
PHC1
PIAS1
PIAS3
PLCL2
POLR2A
PPP1R10
PPP1R11
PPP1R13B
PPP1R13L
PPP1R15A
PPP1R15B
PPP1R16A
PPP1R18
PPP1R1B
PPP1R2
PPP1R26
PPP1R2P3
PPP1R2P9
PPP1R32
PPP1R37
PPP1R3B
PPP1R3C
PPP1R3D
PPP1R3E
PPP1R3G
PPP1R8
PPP1R9A
PPP1R9B
PPP2CA
PREX1
PRKCB
PRKCD
PRR16
PTEN
RANBP9
RB1
RIF1
RPRD2
SFPQ
SFRP1
SH3RF2
SKP1
SLC45A1
SNCAIP
SORL1
SPRED1
STAM
STAU1
SYTL2
TCTEX1D4
TOE1
TOR1AIP1
TOX4
TP53
TP53BP2
TPRN
TUSC3
UBE2Z
ULK1
VDR
WBP11
WDR82
WWTR1
YLPM1
ZBTB11
ZFYVE16
ZFYVE9
ZNF827
Entrez ID
114034
5499
HPRD ID
18212
15942
Ensembl ID
ENSG00000132773
ENSG00000172531
Uniprot IDs
B4DEM6
Q96GM8
P62136
PDB IDs
2FC6
3E7A
3E7B
3EGG
3EGH
3HVQ
3N5U
3V4Y
4G9J
Enriched GO Terms of Interacting Partners
?
MRNA Metabolic Process
RNA Processing
MRNA Processing
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA 3'-end Processing
RNA 3'-end Processing
RNA Metabolic Process
Termination Of RNA Polymerase II Transcription
Gene Expression
Nucleobase-containing Compound Metabolic Process
MRNA Export From Nucleus
DNA-templated Transcription, Termination
RNA Export From Nucleus
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of RNA Splicing
Nuclear Export
MRNA Transport
Nitrogen Compound Metabolic Process
RNA Transport
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Cellular Localization
Nuclear-transcribed MRNA Catabolic Process
RNA Localization
MRNA Catabolic Process
Cytoplasmic Transport
Establishment Of Localization In Cell
Intracellular Transport
RNA Catabolic Process
Positive Regulation Of Synaptic Vesicle Priming
Positive Regulation Of Synaptic Vesicle Exocytosis
Interleukin-7-mediated Signaling Pathway
Regulation Of MRNA Splicing, Via Spliceosome
Nucleocytoplasmic Transport
Cellular Metabolic Process
Nuclear Transport
Negative Regulation Of Hyaluronan Biosynthetic Process
Cellular Response To Norepinephrine Stimulus
Regulation Of Epithelial Cell Proliferation
Regulation Of MRNA Processing
PML Body Organization
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis
Positive Regulation Of Inhibitory Postsynaptic Membrane Potential
Negative Regulation Of T Cell Mediated Cytotoxicity
Cellular Process
Regulation Of Catalytic Activity
Regulation Of Metabolic Process
Negative Regulation Of Catalytic Activity
Regulation Of Phosphorus Metabolic Process
Regulation Of Phosphatase Activity
Regulation Of Dephosphorylation
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Phosphatase Activity
Apoptotic Process
Negative Regulation Of Dephosphorylation
Regulation Of Cellular Component Organization
Programmed Cell Death
Regulation Of Cellular Protein Metabolic Process
Regulation Of Cellular Process
Positive Regulation Of Cellular Protein Metabolic Process
Cell Death
Negative Regulation Of Cellular Metabolic Process
Death
Positive Regulation Of Metabolic Process
Regulation Of Signaling
Positive Regulation Of Protein Metabolic Process
Cell Cycle
Regulation Of Signal Transduction
Regulation Of Protein Metabolic Process
Negative Regulation Of Signal Transduction
Negative Regulation Of Signaling
Cell Cycle Process
Regulation Of Phosphorylation
Intrinsic Apoptotic Signaling Pathway
Regulation Of Cellular Amino Acid Metabolic Process
Organelle Organization
Intracellular Signal Transduction
Regulation Of Protein Phosphorylation
Mitotic Cell Cycle Process
Regulation Of Organelle Organization
Cellular Response To Stress
Mitotic Cell Cycle
Positive Regulation Of Protein Modification Process
Regulation Of Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of Apoptotic Signaling Pathway
Regulation Of Cell Differentiation
Cellular Response To Organic Substance
Response To Organic Substance
Regulation Of Cellular Ketone Metabolic Process
Negative Regulation Of Protein Kinase Activity
Developmental Process
Positive Regulation Of Catalytic Activity
Multicellular Organismal Development
Anatomical Structure Development
Negative Regulation Of Kinase Activity
Tagcloud
?
0x
1x
adamts13
aspm
atp6v0a2
bioinformatic
bl
chickens
col12a1
fowl
grm5
interpretations
jungle
lrp2
obscn
plau
prkdc
resequencing
rnf168
sanger
sl
slv
smyth
stab2
ubc
ubiquitinylation
vitiliginous
vitiligo
xirp1
Tagcloud (Difference)
?
0x
1x
adamts13
aspm
atp6v0a2
bioinformatic
bl
chickens
col12a1
fowl
grm5
interpretations
jungle
lrp2
obscn
plau
prkdc
resequencing
rnf168
sanger
sl
slv
smyth
stab2
ubc
ubiquitinylation
vitiliginous
vitiligo
xirp1
Tagcloud (Intersection)
?