TOE1 and RAB40C

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		TOE1	RAB40C
Gene Name		target of EGR1, member 1 (nuclear)	RAB40C, member RAS oncogene family
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Nuclear Speck	Plasma Membrane Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Nucleic Acid Binding Protein Binding Metal Ion Binding	GTPase Activity GTP Binding GDP Binding
	Biological Process		Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Protein Ubiquitination Regulation Of Exocytosis Rab Protein Signal Transduction Protein Localization To Plasma Membrane
Pathways
Drugs
Diseases
GWAS			Disc degeneration (lumbar) ( 22993228) Height ( 18391950)
Protein-Protein Interactions		25 interactors: ABCF3 AGGF1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83	2 interactors: PSD TOE1
Entrez ID		114034	57799
HPRD ID		18212	10182
Ensembl ID		ENSG00000132773	ENSG00000197562
Uniprot IDs		B4DEM6 Q96GM8	Q5PXE8 Q6PIU5 Q96S21
PDB IDs		2FC6
Enriched GO Terms of Interacting Partners?		MRNA Metabolic Process RNA Processing MRNA Processing RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA 3'-end Processing RNA 3'-end Processing RNA Metabolic Process Termination Of RNA Polymerase II Transcription Gene Expression Nucleobase-containing Compound Metabolic Process MRNA Export From Nucleus DNA-templated Transcription, Termination RNA Export From Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Nuclear Export MRNA Transport Nitrogen Compound Metabolic Process RNA Transport Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Localization Nuclear-transcribed MRNA Catabolic Process RNA Localization MRNA Catabolic Process Cytoplasmic Transport Establishment Of Localization In Cell Intracellular Transport RNA Catabolic Process Positive Regulation Of Synaptic Vesicle Priming Positive Regulation Of Synaptic Vesicle Exocytosis Interleukin-7-mediated Signaling Pathway Regulation Of MRNA Splicing, Via Spliceosome Nucleocytoplasmic Transport Cellular Metabolic Process Nuclear Transport Negative Regulation Of Hyaluronan Biosynthetic Process Cellular Response To Norepinephrine Stimulus Regulation Of Epithelial Cell Proliferation Regulation Of MRNA Processing PML Body Organization Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Negative Regulation Of T Cell Mediated Cytotoxicity Cellular Process
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