TOE1 and CA12

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		TOE1	CA12
Description		target of EGR1, exonuclease	carbonic anhydrase 12
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body Nuclear Body Nuclear Speck	Plasma Membrane Membrane Basolateral Plasma Membrane Apical Plasma Membrane
	Molecular Function	3'-5'-RNA Exonuclease Activity Nucleic Acid Binding Poly(A)-specific Ribonuclease Activity Protein Binding Zinc Ion Binding SnRNA Binding Metal Ion Binding	Carbonate Dehydratase Activity Zinc Ion Binding Lyase Activity Metal Ion Binding
	Biological Process	RNA Metabolic Process SnRNA 3'-end Processing	Estrous Cycle Chloride Ion Homeostasis
Pathways			Reversible hydration of carbon dioxide
Drugs			Benzthiazide Hydroflumethiazide Acetazolamide Zonisamide Ellagic acid
Diseases
GWAS			Daytime nap ( 33568662) Dentures ( 31235808) Number of decayed, missing and filled tooth surfaces ( 31235808) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Refractive error ( 32231278)
Interacting Genes		27 interacting genes: ABCF3 AGGF1 ANXA1 AP2A1 APLP1 CA12 HNRNPF IK IL7R LSM4 OGT PPP1CA PRCC RAB40C RBM39 RBM8A RPS3A SF3B2 SF3B3 SH3GL3 SQSTM1 SRSF6 SUMO1 U2AF1 UNC13B WDR77 WDR83	10 interacting genes: ATP5F1C CUX1 DAXX KATNBL1 LGALS7 MAPK6 MRPL9 RDH11 SGSM2 TOE1
Entrez ID		114034	771
HPRD ID		18212	04464
Ensembl ID		ENSG00000132773	ENSG00000074410
Uniprot IDs		B4DP23 Q96GM8	B3KUB4 O43570
PDB IDs		2FC6	1JCZ 1JD0 4HT2 4KP5 4KP8 4Q0L 4QJ0 4QJO 4QJW 4WW8 5LL5 5LL9 5LLO 5LLP 5MSA 5MSB 6G5L 6G7A 6QN0 6QNG 6QNL 6R6Y 6R71 6RPS 6T5P 6T5Q 7PP9 7PUU 7PUV 7PUW 8CO3
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing Spliceosomal Complex MRNA Processing MRNA Metabolic Process Catalytic Step 2 Spliceosome RNA Metabolic Process Nucleoplasm Nuclear Speck Regulation Of RNA Splicing RNA Processing Nucleic Acid Metabolic Process Macromolecule Metabolic Process U2-type Precatalytic Spliceosome Nucleobase-containing Compound Metabolic Process Protein-RNA Complex Assembly Nucleic Acid Binding Regulation Of MRNA Splicing, Via Spliceosome RS Domain Binding Regulation Of MRNA Processing Glutamatergic Synapse Cadherin Binding Involved In Cell-cell Adhesion RNA Binding Transition Metal Ion Binding U2-type Prespliceosome Assembly U12-type Spliceosomal Complex U2 SnRNP Membraneless Organelle Assembly U2-type Spliceosomal Complex Regulation Of Programmed Cell Death Alpha-2B Adrenergic Receptor Binding Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Positive Regulation Of Synaptic Vesicle Priming Oocyte Axis Specification
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