CHP1 and GAPDH

Number of citations of the paper that reports this interaction (PMID 15312048)
14

Data Source:
HPRD (in vitro)

		CHP1	GAPDH
Gene Name		calcineurin-like EF-hand protein 1	glyceraldehyde-3-phosphate dehydrogenase
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Nucleus Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol Plasma Membrane Focal Adhesion Microtubule Cytoskeleton Transport Vesicle Extracellular Vesicular Exosome	Nucleus Cytoplasm Lipid Particle Cytosol Plasma Membrane Microtubule Cytoskeleton Membrane Ribonucleoprotein Complex Nuclear Membrane Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome GAIT Complex
	Molecular Function	Protein Kinase Inhibitor Activity Transporter Activity Calcium Ion Binding Protein Binding Microtubule Binding Potassium Channel Regulator Activity Kinase Binding Calcium-dependent Protein Binding	Glyceraldehyde-3-phosphate Dehydrogenase (NAD+) (phosphorylating) Activity Protein Binding Microtubule Binding Peptidyl-cysteine S-nitrosylase Activity Identical Protein Binding NADP Binding NAD Binding
	Biological Process	Microtubule Bundle Formation Negative Regulation Of Protein Phosphorylation Carbohydrate Metabolic Process Negative Regulation Of Protein Kinase Activity Protein Export From Nucleus Potassium Ion Transport Small GTPase Mediated Signal Transduction Pathogenesis Negative Regulation Of Phosphatase Activity Calcium Ion-dependent Exocytosis Membrane Docking Glycosaminoglycan Metabolic Process Hyaluronan Metabolic Process Hyaluronan Catabolic Process Cytoplasmic Microtubule Organization Negative Regulation Of Protein Ubiquitination Negative Regulation Of Protein Autophosphorylation Negative Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Protein Import Into Nucleus Small Molecule Metabolic Process Transcytosis Protein Stabilization Positive Regulation Of Protein Transport Protein Oligomerization Regulation Of Intracellular PH Positive Regulation Of Protein Glycosylation Membrane Organization Membrane Fusion Negative Regulation Of Calcineurin-NFAT Signaling Cascade Cellular Response To Acidic PH Positive Regulation Of Protein Targeting To Membrane Regulation Of Neuron Death	Microtubule Cytoskeleton Organization Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Pathogenesis Negative Regulation Of Translation Peptidyl-cysteine S-trans-nitrosylation Small Molecule Metabolic Process Protein Stabilization Neuron Apoptotic Process Oxidation-reduction Process Cellular Response To Interferon-gamma
Pathways		MPS IIIB - Sanfilippo syndrome B Diseases of glycosylation Defective B4GALT7 causes EDS, progeroid type MPS I - Hurler syndrome MPS IX - Natowicz syndrome Defective SLC26A2 causes chondrodysplasias Glycosaminoglycan metabolism Hyaluronan uptake and degradation Defective CHST14 causes EDS, musculocontractural type Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective PAPSS2 causes SEMD-PA MPS IIIA - Sanfilippo syndrome A Myoclonic epilepsy of Lafora Glycogen storage diseases MPS IIID - Sanfilippo syndrome D Hyaluronan metabolism Defective CHST6 causes MCDC1 MPS IIIC - Sanfilippo syndrome C Diseases associated with glycosaminoglycan metabolism Mucopolysaccharidoses Defective EXT2 causes exostoses 2 MPS II - Hunter syndrome Defective B3GAT3 causes JDSSDHD Defective CHST3 causes SEDCJD Defective EXT1 causes exostoses 1, TRPS2 and CHDS MPS IV - Morquio syndrome A MPS IV - Morquio syndrome B Defective CHSY1 causes TPBS Metabolism of carbohydrates MPS VII - Sly syndrome MPS VI - Maroteaux-Lamy syndrome	Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates
Drugs			NADH Nicotinamide-Adenine-Dinucleotide Adenosine-5-Diphosphoribose Thionicotinamide-Adenine-Dinucleotide 4-(2-AMINOETHYL)BENZENESULFONYL FLUORIDE
Diseases
GWAS
Protein-Protein Interactions		9 interactors: GAPDH KIF1B PRSS23 SLC9A1 SLC9A2 SLC9A3 SLC9A4 SLC9A5 STK17B	75 interactors: ACD ACTB ACTC1 ANXA1 ANXA7 APP AR ARL15 ATN1 ATXN1 BID BPGM BTBD2 CAMK1 CAMK2B CAMK4 CDKN1A CDKN2A CHP1 DYNLL1 EGFR FKBP6 GADD45A GAS7 GOT2 GRM1 GSK3B HES1 HNF4G HTT KARS KAT5 KCNE3 LAMA4 LAMTOR5 LIG4 MAPK1 MYOC NFYC NR1H4 OSMR OSTF1 PAFAH1B3 PCDHA4 PCNA PDIA2 PGK1 PLD2 POT1 POU2F2 PPM1E PRDX1 PRKCI PRPF40A PSEN1 PSMD11 RAB2A RBM5 RPA2 S100A6 SERPINB9 SIAH1 SIRT1 SLC2A1 SLC2A4 SMN1 SNCA SUMO4 TERF1 TINF2 TK1 TPPP USP25 YWHAE YWHAQ
Entrez ID		11261	2597
HPRD ID		06101	00713
Ensembl ID		ENSG00000187446	ENSG00000111640
Uniprot IDs		H0YKE7 Q99653	P04406
PDB IDs		2E30	1U8F 1ZNQ 2FEH 3GPD
Enriched GO Terms of Interacting Partners?		Regulation Of PH Hydrogen Ion Transmembrane Transport Sodium Ion Transmembrane Transport Proton Transport Sodium Ion Transport Ion Homeostasis Monovalent Inorganic Cation Transport Metal Ion Transport Chemical Homeostasis Cation Transmembrane Transport Cation Transport Ion Transmembrane Transport Homeostatic Process Transmembrane Transport Ion Transport Neuron Death Sodium Ion Import Across Plasma Membrane Peptidyl-cysteine S-trans-nitrosylation Cell Death Death Sodium Ion Import Cardiac Muscle Cell Contraction Regulation Of The Force Of Heart Contraction By Cardiac Conduction Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of The Force Of Heart Contraction Peptidyl-cysteine S-nitrosylation Positive Regulation Of Fibroblast Apoptotic Process Positive Regulation Of Calcineurin-NFAT Signaling Cascade Pathogenesis Sodium Ion Export Positive Regulation Of NFAT Protein Import Into Nucleus Cellular Response To Acidic PH Positive Regulation Of Action Potential Response To Muscle Stretch Regulation Of Cardiac Muscle Cell Membrane Potential Transport Gastric Acid Secretion Cellular Response To Electrical Stimulus Maintenance Of Cell Polarity Regulation Of Calcineurin-NFAT Signaling Cascade Apoptotic Process Cellular Sodium Ion Homeostasis Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Hyaluronan Catabolic Process Programmed Cell Death Mitochondrion Transport Along Microtubule Cellular Response To PH Positive Regulation Of Sodium Ion Transmembrane Transport Establishment Of Mitochondrion Localization Cellular Response To Epinephrine Stimulus	Developmental Process Regulation Of Cell Death Regulation Of Apoptotic Process Apoptotic Process Programmed Cell Death Cell Death Death System Development Response To Stimulus Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Regulation Of Intracellular Transport Regulation Of Cellular Response To Heat Regulation Of Cellular Component Organization Anatomical Structure Development Regulation Of Establishment Of Protein Localization Positive Regulation Of Apoptotic Process Multicellular Organismal Development Response To Abiotic Stimulus Cellular Response To Stimulus Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Localization Regulation Of Protein Localization Regulation Of Cellular Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of Organelle Organization Neuron Apoptotic Process Cell Cycle Cellular Response To Stress Regulation Of Catalytic Activity Neuron Death Negative Regulation Of Protein Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Catalytic Activity Regulation Of Phosphorylation Cellular Response To Heat Negative Regulation Of Transferase Activity Regulation Of Organelle Organization Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Homeostatic Process Positive Regulation Of Intracellular Transport Cell Differentiation Positive Regulation Of Metabolic Process Cellular Component Assembly Positive Regulation Of Signal Transduction Mitotic Cell Cycle Phase Transition
Tagcloud ?		antisilencing associating chromodomain clr4 comprise coordinates determinant disrupted dissecting dsr eliminating epe1 facultative fission follows h3k9 heterochromatin machinery mechanistically mei4 meiotic mmi1 participates recruits red1 reversibly ssm4 suv39h transacting	apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced
Tagcloud (Difference) ?		antisilencing associating chromodomain clr4 comprise coordinates determinant disrupted dissecting dsr eliminating epe1 facultative fission follows h3k9 heterochromatin machinery mechanistically mei4 meiotic mmi1 participates recruits red1 reversibly ssm4 suv39h transacting	apart caenorhabditis cloning cyst drive elegans ends flanking frame genetics globodera gluconeogenesis glyceraldehyde glycolysis gonads gpd green leader microinjected nematode nucleotides obligatory parasitic pathogenicity potato rostochiensis sl1 spliced
Tagcloud (Intersection) ?