E2F1 and STOML1

Number of citations of the paper that reports this interaction (PMID 20195357)
18

Data Source:
BioGRID (pull down)

		E2F1	STOML1
Gene Name		E2F transcription factor 1	stomatin (EPB72)-like 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Rb-E2F Complex	Cellular_component Integral Component Of Membrane
	Molecular Function	Core Promoter Binding DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding	Molecular_function Protein Binding
	Biological Process	DNA Damage Checkpoint G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Cell Cycle Transcription, DNA-templated Regulation Of Transcription, DNA-templated Apoptotic Process Notch Signaling Pathway Spermatogenesis Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Gene Expression Forebrain Development Anoikis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Fibroblast Proliferation MRNA Stabilization Cellular Response To Fatty Acid Cellular Response To Hypoxia Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Lens Fiber Cell Apoptotic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle	Biological_process
Pathways		Cellular Senescence Activation of BH3-only proteins Oncogene Induced Senescence Assembly of the pre-replicative complex Pre-NOTCH Transcription and Translation G2 Phase G1/S Transition G1/S-Specific Transcription Programmed Cell Death Pre-NOTCH Expression and Processing Mitotic G1-G1/S phases Intrinsic Pathway for Apoptosis E2F mediated regulation of DNA replication Signaling by NOTCH DNA Replication Pre-Initiation G1 Phase M/G1 Transition Regulation of DNA replication G0 and Early G1 CDC6 association with the ORC:origin complex Cell Cycle, Mitotic Activation of NOXA and translocation to mitochondria Cyclin D associated events in G1 Oxidative Stress Induced Senescence Activation of PUMA and translocation to mitochondria Association of licensing factors with the pre-replicative complex Mitotic G2-G2/M phases Inhibition of replication initiation of damaged DNA by RB1/E2F1
Drugs
Diseases
GWAS
Protein-Protein Interactions		70 interactors: ARID3A ATAD2 ATM ATR BRCA1 BRD2 BTRC CCNA1 CCNA2 CDK1 CDK2 CDK3 CDK7 CDKN2A CEBPE CHEK2 CREBBP CTDP1 CUL1 DDB2 E2F6 ERCC3 FHL2 GSK3B GTF2H1 HCFC1 IGF1 KAT5 KDM1A MDM2 MDM4 MGA MNAT1 MYBL2 NCOA3 NCOA6 NCOR2 NDN NDNL2 NFKB1 NPDC1 NRIP1 PARP1 PHB PKIB PRDM2 PURA RARA RB1 RNF144A SERTAD2 SETD7 SKP2 SP1 SP2 SP3 SP4 SPIB STAT1 STOML1 TBP TEAD3 TFDP1 TFDP2 TOPBP1 TP53 TP53BP1 TRRAP VHL YWHAQ	3 interactors: APP E2F1 FBXW7
Entrez ID		1869	9399
HPRD ID		01806	16314
Ensembl ID		ENSG00000101412	ENSG00000067221
Uniprot IDs		Q01094 Q9BSD8	B4DUU5 E7ESC0 H3BRP3 H3BST3 Q4PNR4 Q53HB6 Q9UBI4
PDB IDs		1H24 1O9K 2AZE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of RNA Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Gene Expression Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Regulation Of Cell Cycle Negative Regulation Of Biosynthetic Process Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Process Cell Cycle Phase Transition Cellular Response To DNA Damage Stimulus Transcription Initiation From RNA Polymerase II Promoter Mitotic Cell Cycle Negative Regulation Of Transcription, DNA-templated Cell Cycle Mitotic Cell Cycle Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Process DNA Repair Cellular Response To Stress DNA-templated Transcription, Initiation Intracellular Steroid Hormone Receptor Signaling Pathway G1/S Transition Of Mitotic Cell Cycle	Notch Signaling Pathway Regulation Of Cell Cycle Phase Transition Regulation Of Epidermal Growth Factor-activated Receptor Activity Posttranscriptional Regulation Of Gene Expression Regulation Of Cell Cycle Process Regulation Of Protein Tyrosine Kinase Activity Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Cell Cycle Regulation Of Receptor Activity Regulation Of Cell Cycle G1/S Phase Transition Response To Abiotic Stimulus Negative Regulation Of SREBP Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Triglyceride Biosynthetic Process Synaptic Growth At Neuromuscular Junction Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Collateral Sprouting In Absence Of Injury Negative Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle Lens Fiber Cell Apoptotic Process Negative Regulation Of Hepatocyte Proliferation Positive Regulation Of Proteolysis Collateral Sprouting Axon Midline Choice Point Recognition Negative Regulation Of DNA Endoreduplication Response To Light Stimulus Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Oxidative Stress-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cellular Metabolic Process Axon Choice Point Recognition Anoikis Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Oxidative Stress-induced Cell Death Forebrain Development Response To Radiation Neuron Remodeling Regulation Of DNA Endoreduplication Regulation Of Cellular Ketone Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Hepatocyte Proliferation Positive Regulation Of Epidermal Growth Factor-activated Receptor Activity Regulation Of Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Organ Development Cellular Copper Ion Homeostasis
Tagcloud ?		box coexpression consensus delays displaying dp dps e2fs ectopic emphasizes exit heterodimerization heterodimers lacks members namely pocket possesses possessing preference quiescent refer shares suppresses transactivational tttcccgc tttcgcgc unlike	accelerated asic asic1a asic1b asic3 cassette channel clamp constant contribution currents dorsal drg encode galactosidase ganglion gated modulate neomycin neurones null patch profoundly proton recordings root sensing splice stomatin
Tagcloud (Difference) ?		box coexpression consensus delays displaying dp dps e2fs ectopic emphasizes exit heterodimerization heterodimers lacks members namely pocket possesses possessing preference quiescent refer shares suppresses transactivational tttcccgc tttcgcgc unlike	accelerated asic asic1a asic1b asic3 cassette channel clamp constant contribution currents dorsal drg encode galactosidase ganglion gated modulate neomycin neurones null patch profoundly proton recordings root sensing splice stomatin
Tagcloud (Intersection) ?