DDX23 and MIR7-2

Number of citations of the paper that reports this interaction (PubMedID 28431233)
0

Data Source:
BioGRID (unspecified method)

		DDX23	MIR7-2
Description		DEAD-box helicase 23	microRNA 7-2
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Spliceosomal Complex U5 SnRNP Chromosome Nucleolus U4/U6 X U5 Tri-snRNP Complex Extracellular Exosome Catalytic Step 2 Spliceosome	RISC Complex
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity
	Biological Process	Cis Assembly Of Pre-catalytic Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing R-loop Processing	MiRNA-mediated Post-transcriptional Gene Silencing
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bipolar disorder ( 21926972)	Night sleep phenotypes ( 27126917)
Interacting Genes		29 interacting genes: CEBPA CLK1 ERG MIR106B MIR128-1 MIR138-2 MIR141 MIR143 MIR19B2 MIR200B MIR200C MIR214 MIR25 MIR363 MIR429 MIR7-1 MIR7-2 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7E MIRLET7G MIRLET7I PCM1 RNF10 TERF1 TERF2IP WBP4 WEE2-AS1	83 interacting genes: ADARB1 AIMP1 AIMP2 APOBEC3B AQR ATXN2L C1QBP CELF1 DARS1 DDX1 DDX21 DDX23 DDX3X DDX3Y DHX36 DHX37 EIF2AK2 EPRS1 ERAL1 FAM98A FUS G3BP2 HNRNPA0 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPF HNRNPH1 HNRNPH2 HNRNPH3 HNRNPK HNRNPL HNRNPM HNRNPR IARS1 IGF2BP1 IGF2BP2 IGF2BP3 KARS1 KNOP1 LARP7 LARS1 LIN28A LIN28B LRPPRC MARS1 MATR3 MSI1 MSI2 NOL6 NONO NUDT21 NUFIP2 PDCD11 PLOD1 PTBP1 PTBP3 PUF60 PURA QARS1 RARS1 RBM14 RBM4 RBMS2 RTCA RTCB SF3B1 SF3B2 SF3B3 SFPQ SUGP2 SYMPK SYNCRIP TAF15 TRA2A TRA2B U2SURP UPF1 UTP20 YBX1 YBX2 YBX3 ZNF346
Entrez ID		9416	407044
HPRD ID		09908
Ensembl ID		ENSG00000174243	ENSG00000207703
Uniprot IDs		B3KY11 Q9BUQ8
PDB IDs		3JCR 4NHO 6AH0 6QW6 6QX9 8H6E 8H6J 8Q7W 8Q7X 8Q91 8QOZ 8QP8 8QP9 8QPA 8QPB 8QPK 8QXD 8R08 8R09 8R0A 8R0B 8RC0 8RM5 8Y6O
Enriched GO Terms of Interacting Partners?		MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing RISC Complex Regulatory NcRNA-mediated Gene Silencing MRNA Base-pairing Post-transcriptional Repressor Activity Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Metabolic Process MiRNA-mediated Gene Silencing By MRNA Destabilization MRNA 3'-UTR Binding MiRNA-mediated Gene Silencing By Inhibition Of Translation Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Metabolic Process MRNA Destabilization RNA Destabilization Positive Regulation Of MRNA Catabolic Process Regulation Of Metabolic Process Positive Regulation Of MRNA Metabolic Process Negative Regulation Of Translation Regulation Of MRNA Stability Regulation Of RNA Stability Negative Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Regulation Of MRNA Metabolic Process Negative Regulation Of Interleukin-33 Production Positive Regulation Of Catabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Translation Regulation Of Multicellular Organismal Development Negative Regulation Of Multicellular Organismal Process Extracellular Vesicle Regulation Of Angiogenesis Negative Regulation Of Cell Migration Negative Regulation Of Developmental Process Regulation Of Vasculature Development Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Regulation Of Leukocyte Adhesion To Vascular Endothelial Cell Shelterin Complex Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Angiogenesis Negative Regulation Of Vasculature Development Extracellular Space Nuclear Telomere Cap Complex Negative Regulation Of Blood Vessel Endothelial Cell Migration	RNA Binding Nucleic Acid Binding RNA Processing RNA Metabolic Process RNA Splicing Nucleic Acid Metabolic Process MRNA Processing MRNA Binding MRNA Metabolic Process Nucleobase-containing Compound Metabolic Process Aminoacyl-tRNA Synthetase Multienzyme Complex Nucleus Macromolecule Metabolic Process Regulation Of MRNA Metabolic Process Regulation Of RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Ribonucleoprotein Complex Post-transcriptional Regulation Of Gene Expression Catalytic Step 2 Spliceosome Nucleoplasm Spliceosomal Complex Cytoplasmic Stress Granule Regulation Of Translation MRNA 3'-UTR Binding Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Catabolic Process Negative Regulation Of Translation RNA Stabilization MiRNA Binding Nucleolus TRNA Aminoacylation For Protein Translation Aminoacyl-tRNA Ligase Activity Regulation Of Gene Expression TRNA Aminoacylation Regulation Of RNA Stability MRNA Stabilization Regulation Of Macromolecule Biosynthetic Process RNA Helicase Activity Regulation Of Macromolecule Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Gene Expression Ligase Activity Regulation Of Primary Metabolic Process CRD-mediated MRNA Stabilization MRNA 5'-UTR Binding
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