CORO1A and GIT2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CORO1A	GIT2
Gene Name		coronin, actin binding protein, 1A	G protein-coupled receptor kinase interacting ArfGAP 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Actin Filament Plasma Membrane Cell-cell Junction Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Protein Complex Phagocytic Vesicle Extracellular Vesicular Exosome	Nucleoplasm Focal Adhesion
	Molecular Function	Protein Binding Protein C-terminus Binding Cytoskeletal Protein Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Poly(A) RNA Binding Actin Filament Binding	Protein Binding ARF GTPase Activator Activity Zinc Ion Binding
	Biological Process	Phagolysosome Assembly Calcium Ion Transport Phagocytosis Movement Of Cell Or Subcellular Component Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Leukocyte Chemotaxis Regulation Of Actin Filament Polymerization Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Nerve Growth Factor Signaling Pathway Positive Regulation Of T Cell Proliferation T Cell Homeostasis Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Chemotaxis Negative Regulation Of Actin Nucleation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4	Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of ARF GTPase Activity Positive Regulation Of GTPase Activity Behavioral Response To Pain
Pathways
Drugs
Diseases
GWAS			Metabolic syndrome ( 20694148) Metabolite levels (MHPG) ( 23319000)
Protein-Protein Interactions		17 interactors: ACTB FHL3 FSD2 GIT2 GOLGA2 LMO2 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1	44 interactors: ACTG1 ACTN1 ADRBK1 ARHGEF7 ATF5 C4BPA CALCOCO2 CORO1A E2F2 EDC4 GCH1 GIT1 GUSB HGD HNRNPUL1 IKBKG KCTD5 KRT18 LMNB1 MVP NFKBIB NME2 PAK1 PAK3 PCLO POLR1B PROX1 PXN QPRT RCVRN RUFY1 RUSC2 SAFB2 SH3GLB2 SMAD3 SPOP TGFB1I1 TNFAIP3 TNIP1 TRAF1 TSN UBQLN1 USHBP1 YWHAG
Entrez ID		11151	9815
HPRD ID		05414	09779
Ensembl ID		ENSG00000102879	ENSG00000139436
Uniprot IDs		P31146	F8VXI9 Q14161 Q6FI58
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta Production Behavioral Response To Pain Positive Regulation Of Metabolic Process Immune Response Enzyme Linked Receptor Protein Signaling Pathway Immune System Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Response To Pain Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Biosynthetic Process Regulation Of Focal Adhesion Assembly Heart Morphogenesis Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Junction Assembly Negative Regulation Of CGMP-mediated Signaling Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Termination Regulation Of Immune System Process Multicellular Organismal Development Defense Response Positive Regulation Of Cytokine Production Multicellular Organismal Response To Stress Organ Development Engulfment Of Apoptotic Cell Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Telomere Formation Via Telomerase Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Nitric Oxide Mediated Signal Transduction Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell-matrix Adhesion System Development Positive Regulation Of Behavior Regulation Of Catalytic Activity	Regulation Of Apoptotic Process Regulation Of Cell Death Ephrin Receptor Signaling Pathway Innate Immune Response Response To External Stimulus Enzyme Linked Receptor Protein Signaling Pathway Response To Stimulus Apoptotic Process Regulation Of Signaling Programmed Cell Death Regulation Of Signal Transduction Immune System Process Immune Response Regulation Of Immune System Process Cell Death Regulation Of Metabolic Process Death Positive Regulation Of Immune Response Defense Response Signal Transduction Regulation Of Immune Response Immune Response-regulating Signaling Pathway Adherens Junction Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Immune System Process Focal Adhesion Assembly Positive Regulation Of Metabolic Process Regulation Of Catalytic Activity Regulation Of Phosphorus Metabolic Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Cell-cell Junction Organization Regulation Of Protein Kinase Activity Positive Regulation Of Catalytic Activity Signaling Regulation Of Kinase Activity Cellular Component Assembly Cell Communication Regulation Of Phosphorylation Adherens Junction Assembly Regulation Of Protein Phosphorylation Regulation Of Cellular Component Organization Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Regulation Of Cell Development Cell-substrate Junction Assembly Activation Of MAPK Activity Positive Regulation Of Protein Serine/threonine Kinase Activity Response To Stress Activation Of Innate Immune Response Cell Surface Receptor Signaling Pathway
Tagcloud ?			ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Difference) ?			ancient autophosphorylation coordinates deregulated dimerization exchange gef git1 gtpase guanine hippo hpo interacting mammals melanogaster metazoan oligomeric originally pak pix polarity proteomics rho rtgef salvador scaffold sterile undefined
Tagcloud (Intersection) ?