CORO1A and FHL3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CORO1A	FHL3
Gene Name		coronin, actin binding protein, 1A	four and a half LIM domains 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Actin Filament Plasma Membrane Cell-cell Junction Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Protein Complex Phagocytic Vesicle Extracellular Vesicular Exosome	Stress Fiber Nucleus Focal Adhesion Z Disc
	Molecular Function	Protein Binding Protein C-terminus Binding Cytoskeletal Protein Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Poly(A) RNA Binding Actin Filament Binding	Actin Binding Zinc Ion Binding
	Biological Process	Phagolysosome Assembly Calcium Ion Transport Phagocytosis Movement Of Cell Or Subcellular Component Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Leukocyte Chemotaxis Regulation Of Actin Filament Polymerization Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Nerve Growth Factor Signaling Pathway Positive Regulation Of T Cell Proliferation T Cell Homeostasis Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Chemotaxis Negative Regulation Of Actin Nucleation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4	Muscle Organ Development Actin Cytoskeleton Organization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACTB FHL3 FSD2 GIT2 GOLGA2 LMO2 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1	88 interactors: A1CF ACTB ADAM15 ADAMTSL4 AIMP2 AMBP C14orf105 C9orf116 CDC25B CDC42EP1 CNNM3 CORO1A CSF1 CTBP2 DCDC2B E2F8 EFCAB12 EPHA10 EPM2AIP1 FAM154A FAM71C FAM90A1 FBXL18 FHL2 FHL5 FOSL2 GATA2 GCM2 HIPK1 HYAL2 ITGA7 KIRREL2 KLF3 KLF8 KRTAP12-1 KRTAP12-2 KTI12 LASP1 LMO2 LNX1 MAPK1 MED15 MPZL1 MRPL27 MYBPC1 MYBPHL MZF1 NPRL3 P4HA2 PAK7 PATL1 PHC2 PHF21A PLEKHF2 PPIG PTPN6 QRICH1 RAD21 RBM42 RFX3 RFX6 RHEBL1 RNMTL1 SAP30BP SLAIN1 SLC25A46 SLC44A3 SMAD2 SMAD3 SMAD4 SNRPG SREBF2 SRF TMX3 TRAF3IP2 TRIM27 TRIP6 TRO TTLL10 TYK2 TYMSOS UBE2I UBE2Q1 WNK1 YPEL3 ZNF417 ZNF512B ZNRD1
Entrez ID		11151	2275
HPRD ID		05414	09101
Ensembl ID		ENSG00000102879	ENSG00000183386
Uniprot IDs		P31146	Q13643 Q96C98
PDB IDs			1WYH 2CUQ 2EHE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta Production Behavioral Response To Pain Positive Regulation Of Metabolic Process Immune Response Enzyme Linked Receptor Protein Signaling Pathway Immune System Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Response To Pain Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Biosynthetic Process Regulation Of Focal Adhesion Assembly Heart Morphogenesis Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Junction Assembly Negative Regulation Of CGMP-mediated Signaling Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Termination Regulation Of Immune System Process Multicellular Organismal Development Defense Response Positive Regulation Of Cytokine Production Multicellular Organismal Response To Stress Organ Development Engulfment Of Apoptotic Cell Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Telomere Formation Via Telomerase Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Nitric Oxide Mediated Signal Transduction Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell-matrix Adhesion System Development Positive Regulation Of Behavior Regulation Of Catalytic Activity	RNA Metabolic Process Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Heterocycle Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cellular Process Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Cell Differentiation Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Cell Proliferation Negative Regulation Of RNA Biosynthetic Process Tissue Development Positive Regulation Of Cellular Metabolic Process Cell Death Death Multicellular Organismal Homeostasis Positive Regulation Of Epithelial To Mesenchymal Transition Endoderm Development Negative Regulation Of Cell Growth Embryonic Organ Development Positive Regulation Of Metabolic Process Primary MiRNA Processing Organ Development Apoptotic Process
Tagcloud ?			accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Difference) ?			accompanied adhesion anchorage antiproliferative arrest b1 cip1 downregulated g1 g2 half implicated interfering knockdown lim marked marker member mobility p21 progression regulator sirna suppressed thereby transduction unclear waf1
Tagcloud (Intersection) ?