CORO1A and SPATA20

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CORO1A	SPATA20
Gene Name		coronin, actin binding protein, 1A	spermatogenesis associated 20
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Immunological Synapse Phagocytic Cup Nucleus Cytoplasm Early Endosome Actin Filament Plasma Membrane Cell-cell Junction Membrane Lamellipodium Axon Phagocytic Vesicle Membrane Cortical Actin Cytoskeleton Protein Complex Phagocytic Vesicle Extracellular Vesicular Exosome	Extracellular Region
	Molecular Function	Protein Binding Protein C-terminus Binding Cytoskeletal Protein Binding Protein Homodimerization Activity Phosphatidylinositol 3-kinase Binding Poly(A) RNA Binding Actin Filament Binding	Catalytic Activity
	Biological Process	Phagolysosome Assembly Calcium Ion Transport Phagocytosis Movement Of Cell Or Subcellular Component Actin Filament Organization Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Cell Migration Leukocyte Chemotaxis Regulation Of Actin Filament Polymerization Negative Regulation Of Vesicle Fusion Cell-substrate Adhesion Uropod Organization Nerve Growth Factor Signaling Pathway Positive Regulation Of T Cell Proliferation T Cell Homeostasis Negative Regulation Of Neuron Apoptotic Process Innate Immune Response Homeostasis Of Number Of Cells Within A Tissue Positive Chemotaxis Negative Regulation Of Actin Nucleation Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Early Endosome To Recycling Endosome Transport Cellular Response To Interleukin-4	Multicellular Organismal Development Spermatogenesis Metabolic Process Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ACTB FHL3 FSD2 GIT2 GOLGA2 LMO2 MAGOH NCF4 POLR1C POT1 SMAD3 SMARCD1 SPATA20 STAT3 TAB1 THBS1 YTHDC1	3 interactors: CORO1A ST6GALNAC4 XRN1
Entrez ID		11151	64847
HPRD ID		05414	07961
Ensembl ID		ENSG00000102879	ENSG00000006282
Uniprot IDs		P31146	Q8TB22
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Transforming Growth Factor Beta Production Behavioral Response To Pain Positive Regulation Of Metabolic Process Immune Response Enzyme Linked Receptor Protein Signaling Pathway Immune System Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Catalytic Activity Response To Pain Regulation Of Gene Expression, Epigenetic Positive Regulation Of Cellular Biosynthetic Process Regulation Of Focal Adhesion Assembly Heart Morphogenesis Cellular Response To Growth Factor Stimulus Response To Growth Factor Regulation Of Cell Junction Assembly Negative Regulation Of CGMP-mediated Signaling Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Dendritic Cell Antigen Processing And Presentation Positive Regulation Of DNA Strand Elongation Positive Regulation Of Cellular Metabolic Process DNA-templated Transcription, Termination Regulation Of Immune System Process Multicellular Organismal Development Defense Response Positive Regulation Of Cytokine Production Multicellular Organismal Response To Stress Organ Development Engulfment Of Apoptotic Cell Negative Regulation Of Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Telomere Formation Via Telomerase Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Interaction With Host Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Positive Regulation Of Chemotaxis Negative Regulation Of Cellular Response To Growth Factor Stimulus Positive Regulation Of Gene Expression Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway Positive Regulation Of Extracellular Matrix Assembly Negative Regulation Of Nitric Oxide Mediated Signal Transduction Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Endothelial Cell Chemotaxis Positive Regulation Of Cell-substrate Adhesion Regulation Of Cell-matrix Adhesion System Development Positive Regulation Of Behavior Regulation Of Catalytic Activity	Early Endosome To Recycling Endosome Transport Uropod Organization Negative Regulation Of Vesicle Fusion Nuclear MRNA Surveillance RNA Surveillance Phagolysosome Assembly Histone MRNA Catabolic Process Nerve Growth Factor Signaling Pathway RRNA Catabolic Process Negative Regulation Of Actin Nucleation Histone MRNA Metabolic Process Regulation Of Actin Nucleation Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Cellular Response To Nerve Growth Factor Stimulus Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Positive Chemotaxis Regulation Of Vesicle Fusion T Cell Homeostasis Homeostasis Of Number Of Cells Within A Tissue Phagosome Maturation Cellular Response To Interleukin-4 O-glycan Processing Response To Interleukin-4 Lysosome Organization Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Sialylation Dolichol-linked Oligosaccharide Biosynthetic Process
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