PLSCR1 and CCDC33

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PLSCR1	CCDC33
Gene Name		phospholipid scramblase 1	coiled-coil domain containing 33
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Golgi Apparatus Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Matrix Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Epidermal Growth Factor Receptor Binding Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding
	Biological Process	Phosphatidylserine Biosynthetic Process Apoptotic Process Acute-phase Response Positive Regulation Of Gene Expression Phospholipid Scrambling Platelet Activation Regulation Of Mast Cell Activation Response To Interferon-beta Negative Regulation Of Viral Genome Replication Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription From RNA Polymerase II Promoter Defense Response To Virus Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Pathways
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		125 interactors: ABL1 ADAMTSL4 ADCY7 ANXA11 APP ARNT2 ATG12 ATN1 BACE1 BCL6B C10orf10 C10orf54 C10orf62 CATSPER1 CCDC33 CCER1 CDC42EP1 CHRD CNTFR CPSF3L CPSF6 CRK CRKL CRY1 CTBP1-AS2 CTSZ DAZAP2 DEF6 DHRS1 DLK2 DMRT3 DOCK2 DTX2 EFEMP2 EGFR ENKD1 EP300 ESR2 EWSR1 EXD3 FAM103A1 FBLN1 FBXL18 FRAT1 FRS3 GDPD5 GLRX3 GNAI2 GPRIN2 HEY2 HOXA1 HOXA9 HOXB6 HRG ILF3 IP6K2 KIAA1683 KIF1A KRTAP10-11 KRTAP10-3 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 LASP1 LCE2D LCE3C LCE4A LGALS9C LINC00663 LINC01547 LONRF1 MAPK6 MED15 MGAT5B MVP NECAP2 NEU4 NOC4L NPDC1 NR0B2 NTN4 OGDH P2RY6 PCED1A PGLS PHLDA1 PITX1 PKD2 PLSCR3 PLSCR4 PML PRKCD PRR13 RASD1 RBL1 RERE RGS3 SCNM1 SF1 SHC1 SLC25A6 SLC35A2 SLPI SMARCC1 SMCP SPATA8 SPG7 SPRY2 SRC STK16 TFG TRAF4 TRIM42 VASP VPS37C YIPF3 ZBTB16 ZNF417 ZNF581 ZNF587 ZNF638 ZNF764	91 interactors: ABCF3 ABLIM3 APP ARIH2 ARMC7 ARNT2 BCCIP BLK BLZF1 BYSL CALCOCO2 CCDC102B CCDC85B CCNH CDCA7L CDKN2B CENPP CHCHD3 DGCR6 DIP2A DVL2 EFEMP2 EHMT2 EMC2 EMD FAM124A FAM161A FXR2 GPATCH2L GRN HGS HNRNPF HNRNPK HOOK2 HOXA1 ING5 KANK2 KCTD19 KCTD9 KHDRBS3 KIFC3 KXD1 LDOC1 LMO2 LMO3 MAGED1 MAPK9 MDFI MIPOL1 MOS NAB2 NCK2 NDOR1 NECAB2 NINL OSGIN1 PID1 PIN1 PLSCR1 PNMA1 PNMA2 POLR1C PPP2R3C PRKAB2 PTGER3 PTK6 RAD54B RBMX RHOXF2 SCNM1 SMAD3 SPAG5 SPG21 SSSCA1 STK16 STX11 TGFB1 TMCC2 TRAF2 TRIM37 TRIM42 TSC22D4 TSGA10 TTC19 TUFT1 UBQLN4 USHBP1 VPS52 ZBTB8A ZGPAT ZNF572
Entrez ID		5359	80125
HPRD ID		08855	09959
Ensembl ID		ENSG00000188313	ENSG00000140481
Uniprot IDs		B4DTE8 O15162	Q8N5R6
PDB IDs		1Y2A
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Organ Development RNA Metabolic Process Transcription, DNA-templated Regulation Of Kinase Activity Enzyme Linked Receptor Protein Signaling Pathway Gene Expression Developmental Process RNA Biosynthetic Process Multicellular Organismal Development Regulation Of Protein Kinase Activity Regulation Of Transcription, DNA-templated Regulation Of Signaling Cellular Response To Organic Substance ERBB Signaling Pathway Regulation Of Nucleic Acid-templated Transcription System Development Regulation Of RNA Biosynthetic Process Cellular Response To Growth Factor Stimulus Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Response To Growth Factor Cellular Macromolecule Biosynthetic Process Regulation Of Signal Transduction Regulation Of Protein Phosphorylation Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Central Nervous System Development Response To Organic Substance Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Development Pattern Specification Process Cellular Process Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Fibroblast Growth Factor Receptor Signaling Pathway Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of MAPK Cascade Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Metabolic Process Regulation Of Cellular Protein Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of MAPK Cascade Cellular Response To Fibroblast Growth Factor Stimulus Activation Of Protein Kinase Activity Platelet Activation	Regulation Of Gene Expression Regulation Of Protein Phosphorylation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Phosphorylation Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Protein Kinase Activity Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of Kinase Activity Positive Regulation Of Transcription, DNA-templated Regulation Of Phosphorus Metabolic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Cell Proliferation Negative Regulation Of Phosphorylation Cellular Nitrogen Compound Metabolic Process Immune System Process Transcription From RNA Polymerase II Promoter Cell Cycle Process Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Cellular Process Regulation Of Cell Cycle Response To Organic Substance Organelle Organization Cellular Macromolecule Biosynthetic Process Positive Regulation Of Extracellular Matrix Assembly Positive Regulation Of Metabolic Process Negative Regulation Of Cell Proliferation Positive Regulation Of MAP Kinase Activity Nitrogen Compound Metabolic Process Negative Regulation Of Protein Phosphorylation
Tagcloud ?		actions adaptor adding anchorage attenuation blocking colorectal crc crcs dephosphorylation effectors erks g1 ht29 led monoclonal np1 overexpressed phospholipid retinoblastoma scramblase serve shc src terminus trafficking treating tumorigenesis tumorigenic
Tagcloud (Difference) ?		actions adaptor adding anchorage attenuation blocking colorectal crc crcs dephosphorylation effectors erks g1 ht29 led monoclonal np1 overexpressed phospholipid retinoblastoma scramblase serve shc src terminus trafficking treating tumorigenesis tumorigenic
Tagcloud (Intersection) ?