Wiki-Pi
About
Search
People
Updates
Search
PLSCR1 and HEY2
Number of citations of the paper that reports this interaction (PubMedID
16189514
)
0
Data Source:
HPRD
(two hybrid)
PLSCR1
HEY2
Description
phospholipid scramblase 1
hes related family bHLH transcription factor with YRPW motif 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Golgi Apparatus
Cytosol
Plasma Membrane
Membrane
Membrane Raft
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Transcription Repressor Complex
Molecular Function
Magnesium Ion Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Virus Receptor Activity
DNA Binding
Nuclease Activity
Epidermal Growth Factor Receptor Binding
Calcium Ion Binding
Protein Binding
Zinc Ion Binding
Hydrolase Activity
SH3 Domain Binding
Phospholipid Scramblase Activity
Enzyme Binding
Lead Ion Binding
CD4 Receptor Binding
Mercury Ion Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
DNA Binding
DNA-binding Transcription Factor Activity
Protein Binding
Identical Protein Binding
Histone Deacetylase Binding
Sequence-specific DNA Binding
Protein Dimerization Activity
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Phosphatidylserine Biosynthetic Process
Lipid Transport
Apoptotic Process
Acute-phase Response
Response To Lead Ion
Positive Regulation Of Gene Expression
Plasma Membrane Phospholipid Scrambling
Platelet Activation
Regulation Of Mast Cell Activation
Response To Interferon-beta
Negative Regulation Of Viral Genome Replication
Positive Regulation Of Innate Immune Response
Positive Regulation Of Transcription By RNA Polymerase II
Symbiont Entry Into Host Cell
Negative Regulation Of Phagocytosis
Defense Response To Virus
Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Phosphatidylserine Exposure On Apoptotic Cell Surface
Positive Regulation Of Chromosome Separation
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Negative Regulation Of Transcription By RNA Polymerase II
Blood Vessel Development
Vasculogenesis
Muscular Septum Morphogenesis
Outflow Tract Morphogenesis
Cardiac Conduction System Development
Atrioventricular Valve Development
Aortic Valve Morphogenesis
Pulmonary Valve Morphogenesis
Tricuspid Valve Morphogenesis
Tricuspid Valve Formation
Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation
Endocardial Cushion To Mesenchymal Transition Involved In Heart Valve Formation
Cardiac Ventricle Morphogenesis
Cardiac Left Ventricle Morphogenesis
Cardiac Right Ventricle Morphogenesis
Ventricular Trabecula Myocardium Morphogenesis
Cardiac Muscle Hypertrophy
Regulation Of DNA-templated Transcription
Regulation Of Transcription By RNA Polymerase II
Notch Signaling Pathway
Pattern Specification Process
Heart Development
Anatomical Structure Morphogenesis
Anterior/posterior Axis Specification
Anterior/posterior Pattern Specification
Positive Regulation Of Heart Rate
Regulation Of Gene Expression
Negative Regulation Of Gene Expression
Cardiac Muscle Cell Apoptotic Process
Negative Regulation Of Cardiac Muscle Cell Apoptotic Process
Mesenchymal Cell Development
Cardiac Muscle Hypertrophy In Response To Stress
Ascending Aorta Morphogenesis
Dorsal Aorta Morphogenesis
Umbilical Cord Morphogenesis
Cell Fate Commitment
Regulation Of Inner Ear Auditory Receptor Cell Differentiation
Negative Regulation Of Notch Signaling Pathway
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Neurogenesis
Smooth Muscle Cell Differentiation
Negative Regulation Of Smooth Muscle Cell Differentiation
Ventricular Cardiac Muscle Cell Development
Cardiac Muscle Cell Proliferation
Positive Regulation Of Cardiac Muscle Cell Proliferation
Cardiac Epithelial To Mesenchymal Transition
Heart Trabecula Formation
Cardiac Septum Morphogenesis
Ventricular Septum Morphogenesis
Atrial Septum Morphogenesis
Negative Regulation Of Transcription Initiation By RNA Polymerase II
Labyrinthine Layer Blood Vessel Development
Blood Vessel Endothelial Cell Differentiation
Artery Development
Arterial Endothelial Cell Differentiation
Cardiac Vascular Smooth Muscle Cell Development
Coronary Vasculature Morphogenesis
Pulmonary Artery Morphogenesis
Protein-DNA Complex Assembly
Negative Regulation Of Biomineral Tissue Development
Circulatory System Development
Cochlea Development
Vascular Associated Smooth Muscle Cell Development
Negative Regulation Of Cardiac Vascular Smooth Muscle Cell Differentiation
Regulation Of Vasculogenesis
Pathways
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
RUNX2 regulates osteoblast differentiation
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Cardiogenesis
Drugs
Diseases
GWAS
Gut microbiota (beta diversity) (
27723756
)
Adult body size (
32376654
)
Appendicular lean mass (
33097823
)
Brain morphology (MOSTest) (
32665545
)
Brugada syndrome (
23872634
35210625
32619740
)
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Endometrial cancer (
27135401
30093612
)
Endometrial cancer (endometrioid histology) (
30093612
)
Endometrial endometrioid carcinoma (
27135401
)
Midgestational circulating levels of PCBs (fetal genetic effect) (
28235828
)
Migraine (
27322543
)
Night sleep phenotypes (
27126917
)
Serum metabolite concentrations in chronic kidney disease (
33838163
)
Subcortical volume (MOSTest) (
32665545
)
TPE interval (resting) (
32386560
)
Waist-hip index (
34021172
)
Interacting Genes
132 interacting genes:
ABL1
ADAMTSL4
ADCY7
ANXA11
APP
ARNT2
ATG12
ATN1
BACE1
BCL6B
C10orf62
CATSPER1
CCDC33
CCER1
CDC42EP1
CHRD
CNTFR
CPSF6
CRK
CRKL
CRY1
CTBP1-DT
CTSZ
DAZAP2
DDIAS
DEF6
DEPP1
DHRS1
DLK2
DMRT3
DOCK2
DTX2
EFEMP2
EGFR
ENKD1
EP300
ESR2
EWSR1
EXD3
FAM107A
FBLN1
FBXL18
FRAT1
FRS3
GDPD5
GLRX3
GNAI2
GPRIN2
HEY2
HOXA1
HOXA9
HOXB6
HRG
ILF3
INTS11
IP6K2
IQCN
KIF1A
KRTAP10-11
KRTAP10-3
KRTAP10-9
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP5-6
KRTAP9-2
LASP1
LCE2D
LCE3C
LCE4A
LGALS9C
LINC00663
LINC01547
LONRF1
MAPK6
MDK
MED15
MGAT5B
MVP
NECAP2
NEU4
NOC4L
NPDC1
NR0B2
NTN4
OGDH
P2RY6
PCED1A
PGLS
PHLDA1
PITX1
PKD2
PLSCR3
PLSCR4
PML
PPDPF
PRKCD
PRR13
RAMAC
RASD1
RBL1
RERE
RGS3
RXRB
SCNM1
SF1
SHC1
SLC25A6
SLC35A2
SLPI
SMARCC1
SMCP
SPATA8
SPG7
SPRY2
SRC
STK16
TFG
THBS1
TRAF4
TRIM42
VASP
VPS37C
VSIR
YIPF3
ZBTB16
ZNF417
ZNF581
ZNF587
ZNF638
ZNF688
ZNF764
27 interacting genes:
ARNT
ATXN1
CYSRT1
ENO1
FHL5
HAND1
HAND2
HDAC1
HES1
HOXA1
HSF2BP
KRTAP1-1
KRTAP11-1
KRTAP3-1
KRTAP4-4
KRTAP5-9
KRTAP6-1
KRTAP6-2
KRTAP8-1
NCOR1
PDLIM7
PLSCR1
RBPMS
SIN3A
SIRT1
TRAF1
TRAF4
Entrez ID
5359
23493
HPRD ID
08855
05243
Ensembl ID
ENSG00000188313
ENSG00000135547
Uniprot IDs
C9J7K9
O15162
Q5TF93
Q9UBP5
PDB IDs
1Y2A
Enriched GO Terms of Interacting Partners
?
Enzyme Binding
Ephrin Receptor Binding
Protein Binding
Positive Regulation Of ERK1 And ERK2 Cascade
Regulation Of Cell-substrate Adhesion
Cellular Response To Transforming Growth Factor Beta Stimulus
Keratin Filament
Cellular Response To Growth Factor Stimulus
Regulation Of ERK1 And ERK2 Cascade
Response To Transforming Growth Factor Beta
Intermediate Filament
Response To Growth Factor
Regulation Of Cell Adhesion
Positive Regulation Of MAPK Cascade
Helper T Cell Diapedesis
Shc-EGFR Complex
Positive Regulation Of Cell-substrate Adhesion
Regulation Of Superoxide Metabolic Process
Negative Regulation Of Long-term Synaptic Potentiation
Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Cell Adhesion
Positive Regulation Of Cell Adhesion
Response To Lipid
Hair Cycle
Apoptotic Process
Regulation Of Focal Adhesion Assembly
Regulation Of MAPK Cascade
Cerebellar Neuron Development
Regulation Of Apoptotic Process
Protein Tyrosine Kinase Activator Activity
Cellular Response To Lipid
Morphogenesis Of A Branching Structure
ERBB Signaling Pathway
Regulation Of DNA-templated Transcription
Regulation Of Cell-substrate Junction Organization
Gland Development
Regulation Of RNA Biosynthetic Process
Programmed Cell Death
Cell Death
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Non-membrane Spanning Protein Tyrosine Kinase Activity
Epidermal Growth Factor Binding
System Development
Regulation Of Cell Population Proliferation
Cellular Response To Oxygen-containing Compound
Positive Regulation Of Cell Migration
Regulation Of Programmed Cell Death
Regulation Of Cell-matrix Adhesion
Positive Regulation Of Superoxide Anion Generation
Central Nervous System Neuron Development
Intermediate Filament
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Negative Regulation Of Androgen Receptor Signaling Pathway
Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
Transcription Corepressor Activity
Regulation Of Androgen Receptor Signaling Pathway
Cardiac Neural Crest Cell Development Involved In Outflow Tract Morphogenesis
HLH Domain Binding
Cardiac Right Ventricle Formation
Keratin Filament
Chromatin
Regulation Of Transcription By RNA Polymerase II
Cytosol
Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Identical Protein Binding
Histone Deacetylase Complex
Regulation Of RNA Metabolic Process
Positive Regulation Of RNA Metabolic Process
Cardiac Neural Crest Cell Development Involved In Heart Development
Regulation Of Secondary Heart Field Cardioblast Proliferation
Determination Of Heart Left/right Asymmetry
Transcription Corepressor Binding
Cardiac Ventricle Formation
Negative Regulation Of Transcription By RNA Polymerase II
Cartilage Morphogenesis
E-box Binding
Regulation Of Cardioblast Proliferation
Thioesterase Binding
Positive Regulation Of Phosphate Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Gliogenesis
Transcription Repressor Complex
Artery Morphogenesis
Cardiac Chamber Formation
Protein Dimerization Activity
Regulation Of Cellular Response To Growth Factor Stimulus
DNA Binding
Protein Deacetylation
Protein Lysine Deacetylase Activity
Odontogenesis Of Dentin-containing Tooth
Embryonic Heart Tube Morphogenesis
Regulation Of Phosphorus Metabolic Process
Regulation Of ATP Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Purine Nucleotide Metabolic Process
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?