PLSCR1 and NECAP2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
0

Data Source:
HPRD (two hybrid)

		PLSCR1	NECAP2
Description		phospholipid scramblase 1	NECAP endocytosis associated 2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Exosome	Plasma Membrane Clathrin-coated Pit Membrane Clathrin Vesicle Coat Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Magnesium Ion Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Virus Receptor Activity DNA Binding Nuclease Activity Epidermal Growth Factor Receptor Binding Calcium Ion Binding Protein Binding Zinc Ion Binding Hydrolase Activity SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding Lead Ion Binding CD4 Receptor Binding Mercury Ion Binding	Protein Binding
	Biological Process	Phosphatidylserine Biosynthetic Process Lipid Transport Apoptotic Process Acute-phase Response Response To Lead Ion Positive Regulation Of Gene Expression Plasma Membrane Phospholipid Scrambling Platelet Activation Regulation Of Mast Cell Activation Response To Interferon-beta Negative Regulation Of Viral Genome Replication Positive Regulation Of Innate Immune Response Positive Regulation Of Transcription By RNA Polymerase II Symbiont Entry Into Host Cell Negative Regulation Of Phagocytosis Defense Response To Virus Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Phosphatidylserine Exposure On Apoptotic Cell Surface Positive Regulation Of Chromosome Separation Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity	Endocytosis Protein Transport Vesicle-mediated Transport
Pathways			Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Gut microbiota (beta diversity) ( 27723756)
Interacting Genes		132 interacting genes: ABL1 ADAMTSL4 ADCY7 ANXA11 APP ARNT2 ATG12 ATN1 BACE1 BCL6B C10orf62 CATSPER1 CCDC33 CCER1 CDC42EP1 CHRD CNTFR CPSF6 CRK CRKL CRY1 CTBP1-DT CTSZ DAZAP2 DDIAS DEF6 DEPP1 DHRS1 DLK2 DMRT3 DOCK2 DTX2 EFEMP2 EGFR ENKD1 EP300 ESR2 EWSR1 EXD3 FAM107A FBLN1 FBXL18 FRAT1 FRS3 GDPD5 GLRX3 GNAI2 GPRIN2 HEY2 HOXA1 HOXA9 HOXB6 HRG ILF3 INTS11 IP6K2 IQCN KIF1A KRTAP10-11 KRTAP10-3 KRTAP10-9 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP5-6 KRTAP9-2 LASP1 LCE2D LCE3C LCE4A LGALS9C LINC00663 LINC01547 LONRF1 MAPK6 MDK MED15 MGAT5B MVP NECAP2 NEU4 NOC4L NPDC1 NR0B2 NTN4 OGDH P2RY6 PCED1A PGLS PHLDA1 PITX1 PKD2 PLSCR3 PLSCR4 PML PPDPF PRKCD PRR13 RAMAC RASD1 RBL1 RERE RGS3 RXRB SCNM1 SF1 SHC1 SLC25A6 SLC35A2 SLPI SMARCC1 SMCP SPATA8 SPG7 SPRY2 SRC STK16 TFG THBS1 TRAF4 TRIM42 VASP VPS37C VSIR YIPF3 ZBTB16 ZNF417 ZNF581 ZNF587 ZNF638 ZNF688 ZNF764	6 interacting genes: AP2B1 APP NMI PLSCR1 SNCA TRAF2
Entrez ID		5359	55707
HPRD ID		08855	07674
Ensembl ID		ENSG00000188313	ENSG00000157191
Uniprot IDs		C9J7K9 O15162	F6SKB8 Q9NVZ3
PDB IDs		1Y2A
Enriched GO Terms of Interacting Partners?		Enzyme Binding Ephrin Receptor Binding Protein Binding Positive Regulation Of ERK1 And ERK2 Cascade Regulation Of Cell-substrate Adhesion Cellular Response To Transforming Growth Factor Beta Stimulus Keratin Filament Cellular Response To Growth Factor Stimulus Regulation Of ERK1 And ERK2 Cascade Response To Transforming Growth Factor Beta Intermediate Filament Response To Growth Factor Regulation Of Cell Adhesion Positive Regulation Of MAPK Cascade Helper T Cell Diapedesis Shc-EGFR Complex Positive Regulation Of Cell-substrate Adhesion Regulation Of Superoxide Metabolic Process Negative Regulation Of Long-term Synaptic Potentiation Regulation Of Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Cell Adhesion Positive Regulation Of Cell Adhesion Response To Lipid Hair Cycle Apoptotic Process Regulation Of Focal Adhesion Assembly Regulation Of MAPK Cascade Cerebellar Neuron Development Regulation Of Apoptotic Process Protein Tyrosine Kinase Activator Activity Cellular Response To Lipid Morphogenesis Of A Branching Structure ERBB Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of Cell-substrate Junction Organization Gland Development Regulation Of RNA Biosynthetic Process Programmed Cell Death Cell Death Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Non-membrane Spanning Protein Tyrosine Kinase Activity Epidermal Growth Factor Binding System Development Regulation Of Cell Population Proliferation Cellular Response To Oxygen-containing Compound Positive Regulation Of Cell Migration Regulation Of Programmed Cell Death Regulation Of Cell-matrix Adhesion Positive Regulation Of Superoxide Anion Generation Central Nervous System Neuron Development	Cell Activation Macrophage Activation Regulation Of Endocytosis Enzyme Binding Positive Regulation Of Endocytosis Regulation Of Vesicle-mediated Transport Response To Lead Ion Positive Regulation Of Inflammatory Response Response To External Biotic Stimulus Positive Regulation Of Defense Response Myeloid Leukocyte Activation Regulation Of Neurotransmitter Uptake Leukocyte Activation Cellular Response To Copper Ion Membrane Raft Regulation Of Presynapse Organization Regulation Of Immune System Process Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Amyloid Fibril Formation Microglial Cell Activation Leukocyte Activation Involved In Inflammatory Response Response To Copper Ion Synaptic Vesicle Endocytosis Regulation Of Defense Response Neurotransmitter Secretion Presynaptic Endocytosis Apoptotic Process Chemical Synaptic Transmission Positive Regulation Of Phosphate Metabolic Process Programmed Cell Death Cell Death Regulation Of Immune Response Response To Metal Ion Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Immune System Process Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Reactive Oxygen Species Metabolic Process Response To Other Organism Regulation Of Cellular Component Organization Receptor Internalization Endocytosis Clathrin-coated Pit Positive Regulation Of Protein Localization Amyloid-beta Complex Response To Interleukin-1 Growth Cone Lamellipodium
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?