RDX and ICAM2

Number of citations of the paper that reports this interaction (PMID 11375520)
2

Data Source:
HPRD (in vitro)

		RDX	ICAM2
Gene Name		radixin	intercellular adhesion molecule 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Ruffle Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Focal Adhesion Extrinsic Component Of Membrane Lamellipodium Filopodium T-tubule Cleavage Furrow Stereocilium Apical Part Of Cell Cell Tip Extracellular Vesicular Exosome Cell Periphery	Uropod Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Protein Binding Poly(A) RNA Binding	Integrin Binding
	Biological Process	Positive Regulation Of Gene Expression Microvillus Assembly Apical Protein Localization Actin Filament Capping Establishment Of Endothelial Barrier	Cell Adhesion Single Organismal Cell-cell Adhesion Extracellular Matrix Organization Regulation Of Immune Response
Pathways		Axon guidance L1CAM interactions Recycling pathway of L1	Integrin cell surface interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		16 interactors: ABCC2 ARHGDIA CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR GNA13 ICAM2 ITGB2 L1CAM ROCK1 SLC9A3R1 SLC9A3R2 TSC1	7 interactors: ATP13A2 CD209 EZR ITGAM ITGB2 MSN RDX
Entrez ID		5962	3384
HPRD ID		01534	00888
Ensembl ID		ENSG00000137710	ENSG00000108622
Uniprot IDs		B0YJ88 P35241 Q6PKD3	P13598 Q6FHE2
PDB IDs			1ZXQ
Enriched GO Terms of Interacting Partners?		Membrane To Membrane Docking Cellular Extravasation Negative Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Transporter Activity Negative Regulation Of Ion Transmembrane Transport Adenylate Cyclase-activating G-protein Coupled Receptor Signaling Pathway Regulation Of Sodium:proton Antiporter Activity Negative Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Transmembrane Transport Rho Protein Signal Transduction Negative Regulation Of Sodium Ion Transmembrane Transport Single Organismal Cell-cell Adhesion Cellular Chemical Homeostasis Cell Surface Receptor Signaling Pathway Membrane Docking Negative Regulation Of Ion Transport Negative Regulation Of Sodium Ion Transport Regulation Of Proton Transport Leukocyte Cell-cell Adhesion Leukocyte Tethering Or Rolling Regulation Of Locomotion Cell Adhesion Cellular Homeostasis Microvillus Assembly Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Microvillus Organization Negative Regulation Of Phosphatidylinositol 3-kinase Signaling Regulation Of Cellular Component Organization Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Monocarboxylic Acid Transport Regulation Of Ion Transmembrane Transporter Activity Response To Organonitrogen Compound Regulation Of Transmembrane Transporter Activity Negative Regulation Of Intracellular Signal Transduction G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Blood Coagulation Hemostasis Regulation Of Excretion Chemical Homeostasis Positive Regulation Of Focal Adhesion Assembly Positive Regulation Of Adherens Junction Organization Regulation Of Cell Shape Cell-matrix Adhesion Cellular Ion Homeostasis Movement Of Cell Or Subcellular Component Regulation Of Cell Morphogenesis Regulation Of Sodium Ion Transmembrane Transporter Activity Nervous System Development Response To Amphetamine Regulation Of Phosphoprotein Phosphatase Activity	Leukocyte Cell-cell Adhesion Establishment Of Endothelial Barrier Single Organismal Cell-cell Adhesion Endothelial Cell Development Membrane To Membrane Docking Endothelial Cell Differentiation Endothelium Development Leukocyte Migration Involved In Inflammatory Response Microvillus Assembly Microvillus Organization Cell Adhesion Cellular Extravasation Activated T Cell Proliferation Epithelial Cell Development Leukocyte Migration Tissue Development Neutrophil Chemotaxis Neutrophil Migration Granulocyte Chemotaxis T Cell Proliferation Locomotion Toll-like Receptor 4 Signaling Pathway Regulation Of Immune System Process Membrane Docking Leukocyte Chemotaxis Epithelial Cell Differentiation Toll-like Receptor Signaling Pathway Lymphocyte Proliferation Mononuclear Cell Proliferation Movement Of Cell Or Subcellular Component Integrin-mediated Signaling Pathway Chemotaxis Leukocyte Proliferation Microglia Development Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Peptide Antigen Transport Cell Chemotaxis Regulation Of Cell Shape Cell Development Cell Differentiation Positive Regulation Of Innate Immune Response Innate Immune Response Cell Migration Cellular Response To Manganese Ion Ectodermal Cell Differentiation Cell Motility Immune System Process Virion Attachment To Host Cell
Tagcloud ?		amended atlantic bombing cerifera coast contaminant curled demolition explosive filtering germination hexahydro impacting juvenile metrics morella necrotic ppm seedling shoot shrub succession tnt triazine trinitro trinitrobenzene trinitrotoluene variably woody	aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam3 ighg3 ighm il7r lck lesional separating sfn v2
Tagcloud (Difference) ?		amended atlantic bombing cerifera coast contaminant curled demolition explosive filtering germination hexahydro impacting juvenile metrics morella necrotic ppm seedling shoot shrub succession tnt triazine trinitro trinitrobenzene trinitrotoluene variably woody	aap aat affymetrix alopecia areata ccl5 cd27 cx3cl1 cxcl10 cxcr5 degs distinctly ereg etiopathogenesis favoring fgf18 fgf5 foxc2 hair hu95a icam3 ighg3 ighm il7r lck lesional separating sfn v2
Tagcloud (Intersection) ?