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RDX and EZR
Number of citations of the paper that reports this interaction (PubMedID
38334954
)
77
Data Source:
BioGRID
(cross-linking study, cross-linking study, cross-linking study)
HPRD
(in vivo)
RDX
EZR
Description
radixin
ezrin
Image
No pdb structure
GO Annotations
Cellular Component
Ruffle
Extracellular Space
Cytoplasm
Cytoskeleton
Plasma Membrane
Microvillus
Adherens Junction
Focal Adhesion
Membrane
Apical Plasma Membrane
Lamellipodium
Filopodium
T-tubule
Midbody
Cortical Actin Cytoskeleton
Cleavage Furrow
Stereocilium
Cell Projection
Apical Part Of Cell
Cell Tip
Extracellular Exosome
Cell Periphery
Stereocilium Base
Fibrillar Center
Ruffle
Immunological Synapse
Uropod
Extracellular Space
Cytoplasm
Endosome
Cytosol
Cytoskeleton
Actin Filament
Plasma Membrane
Microvillus
Brush Border
Adherens Junction
Focal Adhesion
Cell Cortex
Actin Cytoskeleton
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Filopodium
Cortical Cytoskeleton
Microvillus Membrane
Vesicle
Ruffle Membrane
Protein-containing Complex
Ciliary Basal Body
Cell Projection
Plasma Membrane Raft
Apical Part Of Cell
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Cell Periphery
Molecular Function
RNA Binding
Actin Binding
Protein Binding
Cytoskeletal Protein Binding
Protein Domain Specific Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Protein Kinase A Binding
ATPase Binding
RNA Binding
Actin Binding
Protein Binding
Microtubule Binding
Cytoskeletal Protein Binding
Protein Domain Specific Binding
Protein Kinase A Catalytic Subunit Binding
Protein Kinase A Regulatory Subunit Binding
Identical Protein Binding
S100 Protein Binding
Cadherin Binding
Cell Adhesion Molecule Binding
Actin Filament Binding
Protein Kinase A Binding
ATPase Binding
Disordered Domain Specific Binding
Biological Process
Regulation Of Cell Shape
Positive Regulation Of Gene Expression
Protein Kinase A Signaling
Microvillus Assembly
Regulation Of Rap Protein Signal Transduction
Cellular Response To Platelet-derived Growth Factor Stimulus
Apical Protein Localization
Establishment Of Protein Localization
Positive Regulation Of Protein Catabolic Process
Barbed-end Actin Filament Capping
Actin Filament Capping
Establishment Of Endothelial Barrier
Establishment Of Protein Localization To Plasma Membrane
Protein Localization To Plasma Membrane
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Postsynaptic Neurotransmitter Receptor Diffusion Trapping
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Organelle Assembly
Positive Regulation Of Protein Localization To Early Endosome
Regulation Of Adherens Junction Organization
Positive Regulation Of Early Endosome To Late Endosome Transport
Negative Regulation Of Transcription By RNA Polymerase II
Intestinal D-glucose Absorption
Sphingosine-1-phosphate Receptor Signaling Pathway
Leukocyte Cell-cell Adhesion
Regulation Of Cell Shape
Positive Regulation Of Gene Expression
Protein Kinase A Signaling
Gland Morphogenesis
Membrane To Membrane Docking
Microvillus Assembly
Actin Cytoskeleton Organization
Astral Microtubule Organization
Protein-containing Complex Localization
Receptor Internalization
Regulation Of Microvillus Length
Negative Regulation Of Interleukin-2 Production
Regulation Of Actin Cytoskeleton Organization
Establishment Or Maintenance Of Apical/basal Cell Polarity
Positive Regulation Of Multicellular Organism Growth
Cortical Microtubule Organization
Establishment Of Epithelial Cell Apical/basal Polarity
Positive Regulation Of Protein Catabolic Process
Filopodium Assembly
Negative Regulation Of T Cell Receptor Signaling Pathway
Actin Filament Bundle Assembly
Establishment Of Centrosome Localization
Establishment Of Endothelial Barrier
Negative Regulation Of ERK1 And ERK2 Cascade
Cellular Response To CAMP
Protein Localization To Plasma Membrane
Protein Localization To Cell Cortex
Postsynaptic Actin Cytoskeleton Organization
Regulation Of Non-canonical NF-kappaB Signal Transduction
Regulation Of Organelle Assembly
Terminal Web Assembly
Positive Regulation Of Protein Localization To Early Endosome
Positive Regulation Of Protein Localization To Plasma Membrane
Negative Regulation Of P38MAPK Cascade
Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways
Recycling pathway of L1
Recycling pathway of L1
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Netrin-1 signaling
Recycling pathway of L1
Recycling pathway of L1
Sensory processing of sound by inner hair cells of the cochlea
Sensory processing of sound by outer hair cells of the cochlea
Drugs
1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS
Cognitive function (
24684796
)
Computer vision syndrome (
33941792
)
Coronary artery disease (
32469254
)
Multiple sclerosis (
31604244
)
Bladder cancer (smoking interaction) (
24662972
)
Blond vs. brown/black hair color (
30531825
)
Brown vs. black hair color (
30531825
)
Hair color (
29662168
)
Refractive error (
32231278
)
Interacting Genes
23 interacting genes:
ABCC2
ARHGDIA
C1QTNF9
CALM1
CPNE1
CPNE2
CPNE4
DRD3
EZR
FTCD
GNA13
ICAM2
ITGB2
L1CAM
LINC01554
NHERF1
NHERF2
PRPF38A
PSME3
RBPMS
ROCK1
TSC1
VPS11
57 interacting genes:
ACTB
ACTC1
ADORA2B
ADRA1B
ARF6
ARHGDIB
CD44
CDH1
CDK5
CEBPA
CFTR
CLIC5
CTNNB1
DLG1
EGFR
ERBB3
FAS
FASLG
GZMM
ICAM1
ICAM2
ICAM3
IQGAP1
L1CAM
LCK
MDM2
MME
MPP3
MSN
NF2
NHERF1
NHERF2
PALLD
PIK3R1
PRKAR2A
PRKCA
PTK2
PTPRC
RDX
ROCK1
RSPH1
S100P
SCYL3
SDC2
SELL
SELP
SLC26A4-AS1
SPN
SUMO2
TBC1D10A
TMEM8B
TSC1
USP1
VCAM1
VPS11
WFDC1
WWOX
Entrez ID
5962
7430
HPRD ID
01534
00475
Ensembl ID
ENSG00000137710
ENSG00000092820
Uniprot IDs
B0YJ88
P35241
Q6PKD3
P15311
PDB IDs
1NI2
4RM8
4RM9
4RMA
7T1K
7T1L
Enriched GO Terms of Interacting Partners
?
Type 2 Metabotropic Glutamate Receptor Binding
Membrane Docking
Type 3 Metabotropic Glutamate Receptor Binding
Membrane To Membrane Docking
Response To Calcium Ion
Phospholipase C-activating Dopamine Receptor Signaling Pathway
Regulation Of Cell Shape
Leukocyte Cell-cell Adhesion
Protein Localization To Membrane
Microvillus Organization
Positive Regulation Of Early Endosome To Late Endosome Transport
Microvillus Assembly
Calcium-dependent Phospholipid Binding
Plasma Membrane
Response To Metal Ion
Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway
Rho Protein Signal Transduction
Microvillus
Receptor Internalization
Uropod
Protein Localization To Plasma Membrane
Cellular Response To Calcium Ion
Regulation Of Intracellular Signal Transduction
Establishment Of Epithelial Cell Apical/basal Polarity
Protein Localization To Cell Periphery
Regulation Of Early Endosome To Late Endosome Transport
Focal Adhesion
Extracellular Exosome
Associative Learning
Cell Periphery
Regulation Of Cell Morphogenesis
G Protein-coupled Dopamine Receptor Signaling Pathway
Cell-matrix Adhesion
Ruffle
Establishment Of Apical/basal Cell Polarity
Polarized Epithelial Cell Differentiation
Establishment Of Monopolar Cell Polarity
Establishment Or Maintenance Of Monopolar Cell Polarity
Negative Regulation Of Intracellular Signal Transduction
Cell-cell Adhesion
Acid Secretion
Microvillus Membrane
Gland Morphogenesis
Establishment Of Epithelial Cell Polarity
Localization Within Membrane
Positive Regulation Of Focal Adhesion Assembly
Cortical Actin Cytoskeleton Organization
Monocarboxylic Acid Transport
Regulation Of Vesicle-mediated Transport
Protein-membrane Adaptor Activity
Plasma Membrane
Cell Adhesion
Cell-cell Adhesion
Focal Adhesion
Leukocyte Cell-cell Adhesion
Cell Migration
Cell Motility
Microvillus
Regulation Of Intracellular Signal Transduction
Lamellipodium
Extracellular Exosome
Membrane
Regulation Of Cell Communication
Regulation Of Signaling
Regulation Of Cell Adhesion
Membrane To Membrane Docking
Regulation Of MAPK Cascade
Positive Regulation Of Cell Communication
Positive Regulation Of Signaling
Leukocyte Tethering Or Rolling
Regulation Of Multicellular Organismal Process
Response To Growth Factor
Positive Regulation Of Transport
Regulation Of Cell-cell Adhesion
Filopodium
Regulation Of Developmental Process
Regulation Of Cell Migration
Cell Projection
Regulation Of Signal Transduction
Leukocyte Adhesion To Vascular Endothelial Cell
Regulation Of Cellular Localization
Regulation Of Apoptotic Process
Positive Regulation Of Early Endosome To Late Endosome Transport
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cellular Component Organization
Positive Regulation Of Signal Transduction
Membrane Docking
Cell Surface
Cellular Developmental Process
Regulation Of Vesicle-mediated Transport
Regulation Of Cell Motility
Regulation Of Programmed Cell Death
Apical Plasma Membrane
Integrin Binding
Developmental Process
Regulation Of Locomotion
Cell-substrate Adhesion
T Cell Activation
Cell-matrix Adhesion
Ruffle
Tagcloud
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Tagcloud (Difference)
?
Tagcloud (Intersection)
?