SMURF2 and RAP1B

  • Number of citations of the paper that reports this interaction (PMID 17318188)
  • 38
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro, in vivo)

SMURF2

RAP1B

Gene Name SMAD specific E3 ubiquitin protein ligase 2 RAP1B, member of RAS oncogene family
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44 29 interactors: A2M ALAS1 APLP1 APP CCT7 CHGB CSAD DDAH2 FAF1 HRAS KMT2B LRIF1 PDHB PKM PRKACA RAB7B RALGDS RAPGEF1 RASSF5 RGL2 RGS2 RPTOR SDF4 SMURF2 TLE1 TP53 UNC119 ZDHHC17 ZNF135
Entrez ID 64750 5908
HPRD ID 06901 01546
Ensembl ID ENSG00000127314
Uniprot IDs Q96DE7 Q9HAU4 B7ZAY2 P61224
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 3BRW 3CF6 4DXA 4HDO 4HDQ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
adp  alphaiibbeta3  alzheimer  apyrase  atherothrombotic  autocrine  besides  ca2  cerebrovascular  collectively  complement  dense  discovered  discoveries  fibrinogen  granule  gtpase  integrin  manage  marginal  p2y  peptides  platelet  platelets  signalling  stimulant  stimulates  syk  thrombus 
Tagcloud (Difference) ?
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
adp  alphaiibbeta3  alzheimer  apyrase  atherothrombotic  autocrine  besides  ca2  cerebrovascular  collectively  complement  dense  discovered  discoveries  fibrinogen  granule  gtpase  integrin  manage  marginal  p2y  peptides  platelet  platelets  signalling  stimulant  stimulates  syk  thrombus 
Tagcloud (Intersection) ?