SMURF2 and SOCS6

  • Number of citations of the paper that reports this interaction (PMID 15761153)
  • 154
  • Data Source:
  • HPRD (in vivo)

SMURF2

SOCS6

Gene Name SMAD specific E3 ubiquitin protein ligase 2 suppressor of cytokine signaling 6
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Systemic lupus erythematosus ( 18204098)
Protein-Protein Interactions 79 interactors: ACBD3 ACOX3 ANAPC5 ARHGAP5 ASH2L AXIN1 BTRC CANX CUEDC1 DAB2 DAZAP2 DGCR2 EGFR EPHA1 FAM175B FKBP4 FLNB GNG2 HDGFRP3 ING2 IRF3 IRF8 KLF5 LAPTM5 LATS1 MAVS NEK6 NKIRAS1 NRAS PPID PRICKLE1 PRICKLE2 RAB13 RAB14 RAB17 RAB22A RAB25 RAN RAP1B RASD2 RASL12 RHOA RHOD RLIM RNF11 RNF111 RNF2 RNF20 RPS27A RRAS2 RUNX2 RUNX3 SF3A2 SKIL SMAD1 SMAD2 SMAD3 SMAD5 SMAD6 SMAD7 SMAP1 SNRNP70 SOCS6 SPG20 SRSF4 TFPI2 TGFBR1 TMEM139 TNPO3 TRAF2 TRAF4 TSSK4 TXNIP UBC UBE2D1 UBE2D3 UBE2L3 YY1 ZBTB44 22 interactors: ACVR1 BMPR1B EFEMP1 INSR IRS2 IRS4 KDM1A KIT PIK3R1 PIK3R2 RBCK1 RELA SMURF2 TCEB1 TCEB2 TGFBR1 TUBA1A TUBB4B UBE2D2 UBE2I WDR89 ZMIZ2
Entrez ID 64750 9306
HPRD ID 06901 05491
Ensembl ID ENSG00000170677
Uniprot IDs Q96DE7 Q9HAU4 O14544
PDB IDs 1ZVD 2DJY 2JQZ 2KXQ 2LTZ 2VIF
Enriched GO Terms of Interacting Partners?
Tagcloud ?
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
6r  c3  castration  cis  constitutively  crpc  erk1  exogenous  express  gp130  il  jak1  jak2  jak3  lncap  ned  neuroendocrine  s17  secretes  sh2  slightly  socs1  socs7  stat3  subline  sublines  suppressors  though  tyk2 
Tagcloud (Difference) ?
autoinhibitory  biochemical  c2  catalytic  controlled  domain  dysregulation  e3  e3s  framework  hect  impaired  interaction  intramolecular  ligases  magnetic  maintaining  nedd4  nmr  noncovalent  regulate  regulators  resonance  state  structural  terminal  transthiolation  ub  ubiquitin 
6r  c3  castration  cis  constitutively  crpc  erk1  exogenous  express  gp130  il  jak1  jak2  jak3  lncap  ned  neuroendocrine  s17  secretes  sh2  slightly  socs1  socs7  stat3  subline  sublines  suppressors  though  tyk2 
Tagcloud (Intersection) ?