FEZ2 and RAI14

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		FEZ2	RAI14
Gene Name		fasciculation and elongation protein zeta 2 (zygin II)	retinoic acid induced 14
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Mitochondrion Cell Cortex Actin Cytoskeleton
	Molecular Function	Protein Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance
Pathways
Drugs
Diseases
GWAS			Left ventricular mass ( 19454037)
Protein-Protein Interactions		18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251	6 interactors: FEZ1 FEZ2 ITSN1 YWHAB YWHAG YWHAQ
Entrez ID		9637	26064
HPRD ID		09213	09416
Ensembl ID		ENSG00000171055	ENSG00000039560
Uniprot IDs		Q9UHY8	Q9P0K7
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production	Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Apoptotic Signaling Pathway Nervous System Development Axon Guidance Regulation Of Mitochondrion Organization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Chemotaxis Positive Regulation Of Cell Death Generation Of Neurons Neuron Projection Morphogenesis Intrinsic Apoptotic Signaling Pathway Neurogenesis Positive Regulation Of Apoptotic Signaling Pathway Cell Morphogenesis Involved In Differentiation Positive Regulation Of Intracellular Transport Neuron Projection Development Cell Projection Morphogenesis Establishment Of Localization In Cell Cell Part Morphogenesis System Development Neuron Development Apoptotic Process Programmed Cell Death Cell Death Death Cell Morphogenesis Cellular Localization Multicellular Organismal Development Neuron Differentiation Cell Projection Organization Anatomical Structure Development Positive Regulation Of Organelle Organization Protein Targeting Locomotion Positive Regulation Of Signal Transduction Regulation Of Intracellular Transport Developmental Process Regulation Of Apoptotic Process Movement Of Cell Or Subcellular Component Regulation Of Cell Death Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Differentiation
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