FEZ2 and C16orf59

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		FEZ2	C16orf59
Gene Name		fasciculation and elongation protein zeta 2 (zygin II)	chromosome 16 open reading frame 59
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251	7 interactors: FEZ1 FEZ2 KDM1A KRTAP10-3 KRTAP10-7 KRTAP10-9 NOTCH2NL
Entrez ID		9637	80178
HPRD ID		09213	07840
Ensembl ID		ENSG00000171055	ENSG00000162062
Uniprot IDs		Q9UHY8	Q7L2K0
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production	Regulation Of Primitive Erythrocyte Differentiation Cell Differentiation Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Axon Guidance Positive Regulation Of Megakaryocyte Differentiation Multicellular Organismal Development Cell Development Positive Regulation Of Hormone Biosynthetic Process Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of Macroautophagy Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Establishment Of Mitochondrion Localization Granulocyte Differentiation Axonogenesis Developmental Process Regulation Of Megakaryocyte Differentiation Negative Regulation Of Histone Methylation Axon Development Nervous System Development Positive Regulation Of Erythrocyte Differentiation Cell Morphogenesis Involved In Neuron Differentiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Chemotaxis Regulation Of Histone H3-K4 Methylation Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Neuron Projection Morphogenesis Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Hormone Biosynthetic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Cell Morphogenesis Involved In Differentiation Negative Regulation Of Autophagy Histone Lysine Demethylation Regulation Of Hormone Metabolic Process Histone Demethylation Regulation Of Erythrocyte Differentiation Mitochondrion Localization Protein Demethylation Neuron Projection Development Cell Projection Morphogenesis Positive Regulation Of Cell Differentiation Regulation Of Signal Transduction By P53 Class Mediator Cell Part Morphogenesis Negative Regulation Of DNA Binding Regulation Of Histone Methylation Positive Regulation Of Neural Precursor Cell Proliferation
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