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FEZ2 and NEK1
Number of citations of the paper that reports this interaction (PMID
14690447
)
15
Data Source:
HPRD
(two hybrid, in vitro)
FEZ2
NEK1
Gene Name
fasciculation and elongation protein zeta 2 (zygin II)
NIMA-related kinase 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Pericentriolar Material
Nucleus
Cytoplasm
Centrosome
Molecular Function
Protein Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
MAP Kinase Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Metal Ion Binding
Biological Process
Signal Transduction
Nervous System Development
Axon Guidance
MAPK Cascade
Activation Of MAPK Activity
Cellular Response To DNA Damage Stimulus
Mitotic Nuclear Division
Response To Ionizing Radiation
Peptidyl-tyrosine Phosphorylation
Cilium Assembly
Cell Division
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
18 interactors:
BRD1
C16orf59
CLASP2
DRAP1
FEZ1
KPNA2
NEK1
PDCD7
PRKCZ
RAB3GAP1
RAI14
SAP30L
SCOC
SMC3
TBC1D25
TLK2
WWC1
ZNF251
13 interactors:
ATRX
CSN2
CTNNAL1
EXOSC4
FEZ1
FEZ2
KIF3A
MRE11A
PPP2R5A
TP53BP1
TSC2
YWHAH
ZNF350
Entrez ID
9637
4750
HPRD ID
09213
06847
Ensembl ID
ENSG00000171055
ENSG00000137601
Uniprot IDs
Q9UHY8
Q5JXL9
Q96PY6
PDB IDs
4APC
4B9D
Enriched GO Terms of Interacting Partners
?
Regulation Of Autophagy
Regulation Of Metabolic Process
Establishment Or Maintenance Of Cell Polarity
Negative Regulation Of Autophagy
Regulation Of Cellular Process
Organelle Organization
Regulation Of Autophagic Vacuole Maturation
Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Regulation Of Cellular Component Organization
Mitotic Nuclear Division
Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Cell Projection Morphogenesis
Positive Regulation Of Interleukin-10 Secretion
Positive Regulation Of T-helper 2 Cell Cytokine Production
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Cell Part Morphogenesis
Establishment Of Cell Polarity
Positive Regulation Of Synaptic Transmission
Membrane Depolarization
Peptidyl-serine Phosphorylation
Cell Division
Regulation Of Organelle Organization
Microtubule Cytoskeleton Organization
Peptidyl-amino Acid Modification
Positive Regulation Of MAPK Cascade
Positive Regulation Of Rab GTPase Activity
Regulation Of Rab GTPase Activity
Regulation Of Rab Protein Signal Transduction
Activation Of Phospholipase D Activity
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Glutamate Secretion
Chromosome Organization
Regulation Of Chromatin Assembly Or Disassembly
Negative Regulation Of Hippo Signaling
Response To Ionizing Radiation
Cell Morphogenesis
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Interleukin-13 Production
Regulation Of Synaptic Plasticity
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Interleukin-5 Production
Positive Regulation Of T Cell Cytokine Production
Response To Stimulus
Regulation Of Cellular Component Organization
Cellular Response To Stimulus
Negative Regulation Of Cellular Metabolic Process
Nervous System Development
Regulation Of Cellular Process
DNA Recombination
Glucocorticoid Catabolic Process
Negative Regulation Of Telomeric RNA Transcription From RNA Pol II Promoter
Regulation Of Dendrite Morphogenesis
DNA Duplex Unwinding
DNA Geometric Change
Double-strand Break Repair Via Homologous Recombination
Recombinational Repair
Generation Of Neurons
DNA Modification
Neurogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Dendrite Development
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Lipid Kinase Activity
Cellular Response To Hydroxyurea
DNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Epidermal Stem Cell Homeostasis
Regulation Of DNA Replication
Signal Transduction
Neuron Differentiation
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Nuclear Cell Cycle DNA Replication
Protein Transport Into Plasma Membrane Raft
Cell Projection Organization
Double-strand Break Repair
System Development
Regulation Of Mitotic Recombination
Plus-end-directed Vesicle Transport Along Microtubule
Protein Localization To Plasma Membrane Raft
Regulation Of Transcription, DNA-templated
Nuclear MRNA Surveillance
DNA Repair
Chemotaxis
Signaling
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
RNA Metabolic Process
Cell Communication
Positive Regulation Of Transcription, DNA-templated
Regulation Of Endocytosis
Regulation Of RNA Metabolic Process
Cullin Deneddylation
Tagcloud
?
axin
cdk1
crb3
dock7
dsh
ezrin
fip200
gadd34
gsk3
hamartin
herc1
hscp
immunoprecipitate
melted
merlin
moesin
nade
p27kip1
p75ntr
pam
patj
pc1
pp2ac
rabaptin
radixin
rheb
rsk1
tbc7
tuberin
Tagcloud (Difference)
?
axin
cdk1
crb3
dock7
dsh
ezrin
fip200
gadd34
gsk3
hamartin
herc1
hscp
immunoprecipitate
melted
merlin
moesin
nade
p27kip1
p75ntr
pam
patj
pc1
pp2ac
rabaptin
radixin
rheb
rsk1
tbc7
tuberin
Tagcloud (Intersection)
?