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FEZ2 and WWC1
Number of citations of the paper that reports this interaction (PMID
16484223
)
14
Data Source:
BioGRID
(two hybrid)
FEZ2
WWC1
Gene Name
fasciculation and elongation protein zeta 2 (zygin II)
WW and C2 domain containing 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Ruffle Membrane
Protein Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Protein Binding
Transcription Coactivator Activity
Protein Binding
Kinase Binding
Protein Binding, Bridging
Protein Complex Scaffold
Biological Process
Signal Transduction
Nervous System Development
Axon Guidance
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Cell Migration
Establishment Of Cell Polarity
Regulation Of Intracellular Transport
Hippo Signaling
Regulation Of Hippo Signaling
Negative Regulation Of Hippo Signaling
Positive Regulation Of MAPK Cascade
Negative Regulation Of Organ Growth
Pathways
Signaling by Hippo
Drugs
Diseases
GWAS
Periodontal microbiota (
22699663
)
Protein-Protein Interactions
18 interactors:
BRD1
C16orf59
CLASP2
DRAP1
FEZ1
KPNA2
NEK1
PDCD7
PRKCZ
RAB3GAP1
RAI14
SAP30L
SCOC
SMC3
TBC1D25
TLK2
WWC1
ZNF251
13 interactors:
AIFM1
CDC5L
CDC73
DDN
FAM219A
FEZ1
FEZ2
HIST1H3A
KIAA0513
LRIF1
MAPK6
PRKCZ
TNIK
Entrez ID
9637
23286
HPRD ID
09213
10033
Ensembl ID
ENSG00000171055
ENSG00000113645
Uniprot IDs
Q9UHY8
Q8IX03
PDB IDs
2Z0U
Enriched GO Terms of Interacting Partners
?
Regulation Of Autophagy
Regulation Of Metabolic Process
Establishment Or Maintenance Of Cell Polarity
Negative Regulation Of Autophagy
Regulation Of Cellular Process
Organelle Organization
Regulation Of Autophagic Vacuole Maturation
Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Regulation Of Cellular Component Organization
Mitotic Nuclear Division
Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Cell Projection Morphogenesis
Positive Regulation Of Interleukin-10 Secretion
Positive Regulation Of T-helper 2 Cell Cytokine Production
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Cell Part Morphogenesis
Establishment Of Cell Polarity
Positive Regulation Of Synaptic Transmission
Membrane Depolarization
Peptidyl-serine Phosphorylation
Cell Division
Regulation Of Organelle Organization
Microtubule Cytoskeleton Organization
Peptidyl-amino Acid Modification
Positive Regulation Of MAPK Cascade
Positive Regulation Of Rab GTPase Activity
Regulation Of Rab GTPase Activity
Regulation Of Rab Protein Signal Transduction
Activation Of Phospholipase D Activity
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Glutamate Secretion
Chromosome Organization
Regulation Of Chromatin Assembly Or Disassembly
Negative Regulation Of Hippo Signaling
Response To Ionizing Radiation
Cell Morphogenesis
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Interleukin-13 Production
Regulation Of Synaptic Plasticity
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Interleukin-5 Production
Positive Regulation Of T Cell Cytokine Production
Regulation Of Nitrogen Compound Metabolic Process
Actin Cytoskeleton Reorganization
Generation Of Neurons
Regulation Of Dendrite Morphogenesis
Neurogenesis
Regulation Of Cellular Process
Regulation Of Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Regulation Of Transcription, DNA-templated
Regulation Of Dendrite Development
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Neuron Differentiation
Regulation Of RNA Metabolic Process
Cell Projection Organization
Cellular Metabolic Process
Positive Regulation Of Interleukin-10 Secretion
Positive Regulation Of T-helper 2 Cell Cytokine Production
Nucleobase-containing Compound Metabolic Process
Response To Stimulus
Protein Localization To Plasma Membrane
Cell Differentiation
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Gene Expression
Activation Of Phospholipase D Activity
Nervous System Development
Regulation Of Gene Expression
Transcription, DNA-templated
Cellular Response To Stimulus
Cell Cycle
Neuron Projection Morphogenesis
Cellular Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Interleukin-13 Production
DNA Packaging
Signal Transduction
Regulation Of Apoptotic DNA Fragmentation
Positive Regulation Of Interleukin-5 Production
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of T Cell Cytokine Production
Histone H2B Ubiquitination
Regulation Of Cell Differentiation
Plasma Membrane Organization
Positive Regulation Of T-helper 2 Cell Differentiation
DNA Replication-dependent Nucleosome Assembly
Activation Of JNKK Activity
Nitrogen Compound Metabolic Process
Tagcloud
?
contextdependent
crossroads
fat1
fat2
fat3
fat4
fathippo
frmd1
frmd6
gammasecretase
lamellipodia
membraneassociated
mob1a
mob1b
mpdz
mpp5
mupp1
pals1
preball
prognostics
sav1
scribblebinding
stemcell
stk3
stk4
vapsbinding
wwc2
wwtr1
yap1
Tagcloud (Difference)
?
contextdependent
crossroads
fat1
fat2
fat3
fat4
fathippo
frmd1
frmd6
gammasecretase
lamellipodia
membraneassociated
mob1a
mob1b
mpdz
mpp5
mupp1
pals1
preball
prognostics
sav1
scribblebinding
stemcell
stk3
stk4
vapsbinding
wwc2
wwtr1
yap1
Tagcloud (Intersection)
?