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FEZ2 and RAB3GAP1
Number of citations of the paper that reports this interaction (PMID
16484223
)
14
Data Source:
BioGRID
(two hybrid)
FEZ2
RAB3GAP1
Gene Name
fasciculation and elongation protein zeta 2 (zygin II)
RAB3 GTPase activating protein subunit 1 (catalytic)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Protein Complex
Extracellular Vesicular Exosome
Endoplasmic Reticulum Tubular Network
Molecular Function
Protein Binding
Rab GTPase Activator Activity
Rab Guanyl-nucleotide Exchange Factor Activity
Rab GTPase Binding
Biological Process
Signal Transduction
Nervous System Development
Axon Guidance
Brain Development
Hypothalamus Development
Positive Regulation Of Rab GTPase Activity
Lipid Particle Organization
Camera-type Eye Development
Regulation Of GTPase Activity
Regulation Of Short-term Neuronal Synaptic Plasticity
Regulation Of Excitatory Postsynaptic Membrane Potential
Face Morphogenesis
Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Pathways
Drugs
Diseases
GWAS
Cholesterol, total (
20686565
)
Corneal structure (
21979947
)
Protein-Protein Interactions
18 interactors:
BRD1
C16orf59
CLASP2
DRAP1
FEZ1
KPNA2
NEK1
PDCD7
PRKCZ
RAB3GAP1
RAI14
SAP30L
SCOC
SMC3
TBC1D25
TLK2
WWC1
ZNF251
8 interactors:
FEZ1
FEZ2
RAB22A
RAB39A
RAB39B
RAB3GAP2
RPH3AL
WDR7
Entrez ID
9637
22930
HPRD ID
09213
16002
Ensembl ID
ENSG00000171055
ENSG00000115839
Uniprot IDs
Q9UHY8
B9A6J2
C9J837
Q15042
PDB IDs
Enriched GO Terms of Interacting Partners
?
Regulation Of Autophagy
Regulation Of Metabolic Process
Establishment Or Maintenance Of Cell Polarity
Negative Regulation Of Autophagy
Regulation Of Cellular Process
Organelle Organization
Regulation Of Autophagic Vacuole Maturation
Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter
Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization
Regulation Of Excitatory Postsynaptic Membrane Potential
Regulation Of Postsynaptic Membrane Potential
Regulation Of Cellular Component Organization
Mitotic Nuclear Division
Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Cell Cycle
Negative Regulation Of Cellular Metabolic Process
Cellular Metabolic Process
Cell Projection Morphogenesis
Positive Regulation Of Interleukin-10 Secretion
Positive Regulation Of T-helper 2 Cell Cytokine Production
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Cell Part Morphogenesis
Establishment Of Cell Polarity
Positive Regulation Of Synaptic Transmission
Membrane Depolarization
Peptidyl-serine Phosphorylation
Cell Division
Regulation Of Organelle Organization
Microtubule Cytoskeleton Organization
Peptidyl-amino Acid Modification
Positive Regulation Of MAPK Cascade
Positive Regulation Of Rab GTPase Activity
Regulation Of Rab GTPase Activity
Regulation Of Rab Protein Signal Transduction
Activation Of Phospholipase D Activity
Negative Regulation Of DNA Endoreduplication
Positive Regulation Of Glutamate Secretion
Chromosome Organization
Regulation Of Chromatin Assembly Or Disassembly
Negative Regulation Of Hippo Signaling
Response To Ionizing Radiation
Cell Morphogenesis
Regulation Of Intracellular Signal Transduction
Positive Regulation Of Interleukin-13 Production
Regulation Of Synaptic Plasticity
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Interleukin-5 Production
Positive Regulation Of T Cell Cytokine Production
Rab Protein Signal Transduction
Intracellular Protein Transport
Establishment Of Localization In Cell
Cellular Localization
Cellular Protein Localization
Protein Transport
Ras Protein Signal Transduction
Establishment Of Protein Localization
Intracellular Transport
Protein Localization
Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization
Regulation Of Vesicle Size
Vesicle-mediated Transport
Small GTPase Mediated Signal Transduction
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Phagosome-lysosome Fusion
Transport
Phagosome Acidification
Negative Regulation Of Macroautophagy
Phagolysosome Assembly
Establishment Of Mitochondrion Localization
Intracellular PH Reduction
Axon Guidance
PH Reduction
Tagcloud
?
acidic
adaptor
anchored
binds
catalytic
compartment
consists
envelope
ergic
etc
execute
ff
ffat
golgi
gtpase
heterodimer
motif
phenylalanines
potently
recruit
reduces
substitution
tail
traffic
vap
vesicle
Tagcloud (Difference)
?
acidic
adaptor
anchored
binds
catalytic
compartment
consists
envelope
ergic
etc
execute
ff
ffat
golgi
gtpase
heterodimer
motif
phenylalanines
potently
recruit
reduces
substitution
tail
traffic
vap
vesicle
Tagcloud (Intersection)
?