FEZ2 and ZNF251

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		FEZ2	ZNF251
Gene Name		fasciculation and elongation protein zeta 2 (zygin II)	zinc finger protein 251
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus
	Molecular Function	Protein Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Metal Ion Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251	5 interactors: FEZ1 FEZ2 MDC1 PAXIP1 SMAD1
Entrez ID		9637	90987
HPRD ID		09213	19696
Ensembl ID		ENSG00000171055	ENSG00000198169
Uniprot IDs		Q9UHY8	Q9BRH9
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production	Regulation Of Dendrite Morphogenesis Regulation Of Dendrite Development Positive Regulation Of Histone H3-K36 Methylation Anatomical Structure Morphogenesis Positive Regulation Of Neuron Projection Development DNA Recombination Connective Tissue Development Primary MiRNA Processing Positive Regulation Of Cell Projection Organization Locomotion Osteoblast Fate Commitment Chorion Development Cellular Response To Stimulus Positive Regulation Of Neuron Differentiation Cell Differentiation Intra-S DNA Damage Checkpoint Movement Of Cell Or Subcellular Component Regulation Of Neuron Projection Development SMAD Protein Complex Assembly Generation Of Neurons Axon Guidance Negative Regulation Of Macroautophagy Positive Regulation Of Neurogenesis Neurogenesis Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Mesodermal Cell Fate Commitment Positive Regulation Of Histone H3-K4 Methylation Establishment Of Mitochondrion Localization Positive Regulation Of DNA-templated Transcription, Initiation Regulation Of Cell Morphogenesis Regulation Of Cell Projection Organization System Development Cardiac Muscle Cell Proliferation Positive Regulation Of Cell Development Production Of MiRNAs Involved In Gene Silencing By MiRNA Positive Regulation Of Histone Acetylation Cellular Response To BMP Stimulus Regulation Of DNA-templated Transcription, Initiation Axonogenesis Regulation Of Cellular Component Organization Regulation Of Histone H3-K4 Methylation Regulation Of Neuron Differentiation Response To Stimulus Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Isotype Switching Positive Regulation Of Protein Acetylation Mesodermal Cell Differentiation Axon Development Cellular Response To Growth Factor Stimulus Cell Morphogenesis Involved In Neuron Differentiation
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