FEZ2 and CLASP2

Number of citations of the paper that reports this interaction (PMID 16484223)
14

Data Source:
BioGRID (two hybrid)

		FEZ2	CLASP2
Gene Name		fasciculation and elongation protein zeta 2 (zygin II)	cytoplasmic linker associated protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Condensed Chromosome Kinetochore Cytoplasm Golgi Apparatus Trans-Golgi Network Microtubule Organizing Center Kinetochore Microtubule Cytosol Microtubule Cytoplasmic Microtubule Plasma Membrane Cell Cortex Membrane Ruffle Membrane
	Molecular Function	Protein Binding	Protein Binding Galactoside 2-alpha-L-fucosyltransferase Activity Microtubule Plus-end Binding
	Biological Process	Signal Transduction Nervous System Development Axon Guidance	Mitotic Cell Cycle Microtubule Nucleation Negative Regulation Of Microtubule Depolymerization Mitotic Nuclear Division Establishment Or Maintenance Of Cell Polarity Axon Guidance Microtubule Organizing Center Organization Regulation Of Microtubule Polymerization Or Depolymerization Regulation Of Microtubule-based Process Microtubule Anchoring Fucosylation Cell Division
Pathways			Role of Abl in Robo-Slit signaling Mitotic Prometaphase Axon guidance Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion Mitotic Anaphase Signaling by Robo receptor Mitotic Metaphase and Anaphase Cell Cycle, Mitotic M Phase
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: BRD1 C16orf59 CLASP2 DRAP1 FEZ1 KPNA2 NEK1 PDCD7 PRKCZ RAB3GAP1 RAI14 SAP30L SCOC SMC3 TBC1D25 TLK2 WWC1 ZNF251	7 interactors: CLIP1 CLIP2 CSNK2A1 FEZ1 FEZ2 MAPRE1 MAPRE2
Entrez ID		9637	23122
HPRD ID		09213	12054
Ensembl ID		ENSG00000171055	ENSG00000163539
Uniprot IDs		Q9UHY8	B2RTR1 O75122
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Autophagy Regulation Of Metabolic Process Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Autophagy Regulation Of Cellular Process Organelle Organization Regulation Of Autophagic Vacuole Maturation Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Positive Regulation Of Glutamate Neurotransmitter Secretion In Response To Membrane Depolarization Regulation Of Excitatory Postsynaptic Membrane Potential Regulation Of Postsynaptic Membrane Potential Regulation Of Cellular Component Organization Mitotic Nuclear Division Positive Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Cell Cycle Negative Regulation Of Cellular Metabolic Process Cellular Metabolic Process Cell Projection Morphogenesis Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell Part Morphogenesis Establishment Of Cell Polarity Positive Regulation Of Synaptic Transmission Membrane Depolarization Peptidyl-serine Phosphorylation Cell Division Regulation Of Organelle Organization Microtubule Cytoskeleton Organization Peptidyl-amino Acid Modification Positive Regulation Of MAPK Cascade Positive Regulation Of Rab GTPase Activity Regulation Of Rab GTPase Activity Regulation Of Rab Protein Signal Transduction Activation Of Phospholipase D Activity Negative Regulation Of DNA Endoreduplication Positive Regulation Of Glutamate Secretion Chromosome Organization Regulation Of Chromatin Assembly Or Disassembly Negative Regulation Of Hippo Signaling Response To Ionizing Radiation Cell Morphogenesis Regulation Of Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Production Regulation Of Synaptic Plasticity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Interleukin-5 Production Positive Regulation Of T Cell Cytokine Production	Cell Cycle Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Microtubule Polymerization Mitotic Nuclear Division Cell Cycle Process Axon Guidance Regulation Of Microtubule Polymerization Or Depolymerization Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Cell Morphogenesis Involved In Differentiation Regulation Of Microtubule Cytoskeleton Organization Regulation Of Cellular Component Organization Protein Transport Into Plasma Membrane Raft Positive Regulation Of Microtubule Plus-end Binding Regulation Of Microtubule-based Process Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Protein Localization To Plasma Membrane Raft Regulation Of Organelle Organization Neuron Development Cell Morphogenesis Protein Localization To Microtubule Neuron Differentiation Cell Projection Organization Protein Transport Into Membrane Raft Protein Localization To Membrane Raft Locomotion Regulation Of Protein Complex Assembly Positive Regulation Of Microtubule Polymerization Negative Regulation Of Macroautophagy Negative Regulation Of Microtubule Polymerization Establishment Of Mitochondrion Localization Movement Of Cell Or Subcellular Component Protein Transport Within Lipid Bilayer Cell Division Generation Of Neurons Protein Localization To Cytoskeleton Neurogenesis Regulation Of Cytoskeleton Organization Cell Development Response To External Stimulus Negative Regulation Of Autophagy Mitochondrion Localization Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation
Tagcloud ?			1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b microtubule mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed
Tagcloud (Difference) ?			1b abortive axon axonal collapsin conditioned cone counteracted crmp cytoskeletal depleted dissect glycogen gsk3beta linker map1b microtubule mimetic myelin neurite optimize outgrowth phospho prevailing regeneration regenerative regrowth scar speed
Tagcloud (Intersection) ?