TNPO1

Gene Name		transportin 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport
Drugs
Diseases
GWAS
Protein-protein Interactions		17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19
Entrez ID		3842
HPRD ID		04210
Ensembl ID		ENSG00000083312
Uniprot IDs		Q92973
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process
Tagcloud ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately