TNPO1 and SRP19

Number of citations of the paper that reports this interaction (PMID 11682607)
14

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TNPO1	SRP19
Gene Name		transportin 1	signal recognition particle 19kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding	7S RNA Binding Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process	Translation Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Response To Drug Cellular Protein Metabolic Process
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport	Translation SRP-dependent cotranslational protein targeting to membrane
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19	6 interactors: IPO5 IPO7 IPO8 KPNA1 SRP54 TNPO1
Entrez ID		3842	6728
HPRD ID		04210	01644
Ensembl ID		ENSG00000083312
Uniprot IDs		Q92973	P09132
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ	1JID 1MFQ 1RY1 2J37 3KTV
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process	Intracellular Protein Transport Establishment Of Protein Localization To Organelle Protein Import Into Nucleus Nuclear Import Protein Targeting Protein Import Protein Localization To Organelle Protein Localization To Nucleus Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Cytoplasmic Transport Nucleocytoplasmic Transport Nuclear Transport Protein Localization Establishment Of Localization In Cell Cellular Localization NLS-bearing Protein Import Into Nucleus Viral Process Transport Positive Regulation Of Protein Import Into Nucleus SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition SRP-dependent Cotranslational Protein Targeting To Membrane, Translocation Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Regulation Of Protein Localization To Nucleus Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Intracellular Transport Regulation Of Intracellular Protein Transport Ribosomal Protein Import Into Nucleus Positive Regulation Of Protein Transport Regulation Of Intracellular Transport Apoptotic DNA Fragmentation Intracellular Transport Of Virus Protein Import Into Nucleus, Translocation Apoptotic Nuclear Changes Regulation Of Protein Transport Regulation Of Establishment Of Protein Localization Positive Regulation Of Transport Intracellular Protein Transmembrane Transport Cellular Response To Amino Acid Stimulus Regulation Of Protein Localization Protein Transmembrane Transport Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Regulation Of DNA Recombination Execution Phase Of Apoptosis Response To Stimulus
Tagcloud ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	5q22 adjusted apc caner chose cnv copy discovering exon9 fluorophores gastric integer interrogate intron8 losses obtain original platform probe probes reep5 searched sought surrounding taqman transformed variation volunteers yielded
Tagcloud (Difference) ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	5q22 adjusted apc caner chose cnv copy discovering exon9 fluorophores gastric integer interrogate intron8 losses obtain original platform probe probes reep5 searched sought surrounding taqman transformed variation volunteers yielded
Tagcloud (Intersection) ?