TNPO1 and RPL23A

Number of citations of the paper that reports this interaction (PMID 9687515)
135

Data Source:
HPRD (in vitro)

		TNPO1	RPL23A
Gene Name		transportin 1	ribosomal protein L23a
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Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium	Nucleus Cytosol Cytosolic Large Ribosomal Subunit TORC2 Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding	Nucleotide Binding Structural Constituent Of Ribosome Protein Binding RRNA Binding Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Cell Proliferation Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19	4 interactors: CTPS2 IPO5 IPO7 TNPO1
Entrez ID		3842	6147
HPRD ID		04210	15998
Ensembl ID		ENSG00000083312
Uniprot IDs		Q92973	A8MUS3 P62750
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ	3J3B
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process	Protein Import Into Nucleus Nuclear Import Protein Import Protein Localization To Nucleus Nucleocytoplasmic Transport Nuclear Transport Establishment Of Protein Localization To Organelle Protein Targeting Protein Localization To Organelle Viral Process Cytoplasmic Transport Intracellular Protein Transport 'de Novo' CTP Biosynthetic Process Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport Ribosomal Protein Import Into Nucleus Protein Localization NLS-bearing Protein Import Into Nucleus Establishment Of Localization In Cell Nucleobase-containing Small Molecule Interconversion Cellular Localization Protein Import Into Nucleus, Translocation CTP Biosynthetic Process Glutamine Metabolic Process Pyrimidine Ribonucleotide Biosynthetic Process Pyrimidine Nucleoside Biosynthetic Process Cellular Response To Amino Acid Stimulus Pyrimidine Nucleotide Biosynthetic Process Pyrimidine Nucleoside Metabolic Process Pyrimidine Nucleotide Metabolic Process Nucleoside Triphosphate Biosynthetic Process Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Response To Amino Acid
Tagcloud ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	60s becomes carry delays disruptions durable embryos endoderm expand extra fail heterozygotes hi2582 hi3655b homozygous hpf initiate larvae morphogenesis pancreas pancreatic progenitors properly ptf1a recoverable ribosomal ribosome rpl6
Tagcloud (Difference) ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	60s becomes carry delays disruptions durable embryos endoderm expand extra fail heterozygotes hi2582 hi3655b homozygous hpf initiate larvae morphogenesis pancreas pancreatic progenitors properly ptf1a recoverable ribosomal ribosome rpl6
Tagcloud (Intersection) ?