TNPO1 and ELAVL1

Number of citations of the paper that reports this interaction (PMID 15037768)
38

Data Source:
HPRD (in vitro, in vivo)

		TNPO1	ELAVL1
Gene Name		transportin 1	ELAV like RNA binding protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding	Nucleotide Binding RNA Binding Double-stranded RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding AU-rich Element Binding Protein Kinase Binding MRNA 3'-UTR AU-rich Region Binding Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process	Multicellular Organismal Development Gene Expression Positive Regulation Of Translation MRNA Stabilization 3'-UTR-mediated MRNA Stabilization Regulation Of Stem Cell Maintenance
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport	Regulation of mRNA stability by proteins that bind AU-rich elements HuR stabilizes mRNA
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19	35 interactors: ANP32A ANP32B APOE CARM1 CELF2 CHEK2 CTNNB1 ERG GJB3 HNRNPK HOTAIR IL7R KPNA1 KPNB1 MIRLET7B MIRLET7I NOS3 PAIP2 PLAU PLAUR PRKCA PRKCD PRKCE PSEN2 PTBP1 PTBP2 PTGS2 RBFOX2 SDCBP SET SREK1 TNPO1 TNPO2 VEGFA XIAP
Entrez ID		3842	1994
HPRD ID		04210	16025
Ensembl ID		ENSG00000083312	ENSG00000066044
Uniprot IDs		Q92973	B4DVB8 Q15717
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ	3HI9 4ED5 4EGL 4FXV
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process	Regulation Of Wound Healing Regulation Of Blood Coagulation Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Positive Regulation Of Transport Negative Regulation Of Wound Healing Apoptotic Process Regulation Of Protein Metabolic Process Programmed Cell Death Negative Regulation Of Cellular Protein Metabolic Process Cell Death Death Regulation Of Platelet Activation Regulation Of Metabolic Process Cell Communication Signal Transduction Negative Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Ion Transport Regulation Of Nitrogen Compound Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Receptor Activity Signaling Response To Abiotic Stimulus Blood Coagulation Negative Regulation Of Platelet Activation Hemostasis Regulation Of Epithelial Cell Migration Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Cellular Response To Stimulus Regulation Of Apoptotic Process Regulation Of Cell Proliferation Response To External Stimulus Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Positive Regulation Of Blood Vessel Endothelial Cell Migration Cellular Response To Organic Substance Regulation Of Cell Death Response To Wounding Blood Circulation Response To Cytokine Execution Phase Of Apoptosis Positive Regulation Of Cellular Component Biogenesis Regulation Of Cellular Ketone Metabolic Process Negative Regulation Of Cell Death Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Epithelial Cell Migration Vasculature Development RNA Splicing Regulation Of Peptidyl-tyrosine Phosphorylation
Tagcloud ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	bace1 bingo cdk2 clustering criterion cytoscape degs downloaded glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plp1 plug software string webgestalt wee1
Tagcloud (Difference) ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	bace1 bingo cdk2 clustering criterion cytoscape degs downloaded glioma gse31262 hierarchical kif23 kobas language limma log2fc mbp multtest myelination omnibus ontology package pheatmap plp1 plug software string webgestalt wee1
Tagcloud (Intersection) ?