TNPO1 and HNRNPA1

Number of citations of the paper that reports this interaction (PMID 9144189)
59

Data Source:
HPRD (in vitro)

		TNPO1	HNRNPA1
Gene Name		transportin 1	heterogeneous nuclear ribonucleoprotein A1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Extracellular Vesicular Exosome Primary Cilium	Nucleoplasm Spliceosomal Complex Cytoplasm Membrane Ribonucleoprotein Complex Intermediate Filament Cytoskeleton Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Ran GTPase Binding Poly(A) RNA Binding	Nucleotide Binding Single-stranded DNA Binding RNA Binding Single-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Import Into Nucleus, Translocation Organelle Organization Gene Expression Viral Process	MRNA Splicing, Via Spliceosome MRNA Processing RNA Export From Nucleus RNA Splicing Gene Expression Viral Process MRNA Transport Nuclear Export Nuclear Import
Pathways		Regulation of mRNA stability by proteins that bind AU-rich elements Organelle biogenesis and maintenance Assembly of the primary cilium Tristetraprolin (TTP) destabilizes mRNA Intraflagellar transport	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		17 interactors: ELAVL1 HIST2H2BE HIST3H3 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RPL23A RPL5 RPS7 SRP19	32 interactors: ABHD16A APP ERG FEN1 HIPK3 HIST3H3 HMGA1 HNRNPH3 KHSRP NFKBIA NR0B2 NR3C1 PABPN1 PHYHIP PPIL1 PRKDC PRMT1 PRMT2 PRMT3 PRRC2A RNF14 RPL21 SAFB SREK1 SRPK1 SUFU TFEC TNPO1 TRA2B TTF2 XRN1 YWHAQ
Entrez ID		3842	3178
HPRD ID		04210	01242
Ensembl ID		ENSG00000083312	ENSG00000135486
Uniprot IDs		Q92973	P09651
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ	1HA1 1L3K 1PGZ 1PO6 1U1K 1U1L 1U1M 1U1N 1U1O 1U1P 1U1Q 1U1R 1UP1 2H4M 2LYV 2UP1
Enriched GO Terms of Interacting Partners?		Cytoplasmic Transport Viral Life Cycle Viral Process Viral Transcription Intracellular Transport Establishment Of Protein Localization To Organelle MRNA Transport RNA Transport Protein Targeting Nucleocytoplasmic Transport Nuclear Transport RNA Localization Protein Localization To Organelle Establishment Of Localization In Cell Nuclear Import Cellular Localization Gene Expression Intracellular Protein Transport Protein Transport Mitotic Nuclear Envelope Disassembly Establishment Of Protein Localization Nuclear Export Nuclear Envelope Disassembly Membrane Organization Cellular Protein Localization Protein Localization Nuclear Envelope Organization RNA Export From Nucleus Glucose Transport Hexose Transport SRP-dependent Cotranslational Protein Targeting To Membrane Cotranslational Protein Targeting To Membrane Protein Targeting To ER Regulation Of Glucose Transport Establishment Of Protein Localization To Endoplasmic Reticulum MRNA Metabolic Process Protein Import Into Nucleus Transport Nucleus Organization Protein Localization To Endoplasmic Reticulum Carbohydrate Transport Protein Import Protein Targeting To Membrane Protein Localization To Nucleus Nucleobase-containing Compound Metabolic Process RNA Catabolic Process Nuclear Pore Complex Assembly Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Biosynthetic Process	MRNA Metabolic Process RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process MRNA Processing Regulation Of Gene Expression Nitrogen Compound Metabolic Process RNA Splicing Regulation Of Nitrogen Compound Metabolic Process RNA Processing Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Chromosome Organization Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Peptidyl-arginine N-methylation Positive Regulation Of Gene Expression Histone Arginine Methylation Peptidyl-arginine Methylation Intracellular Receptor Signaling Pathway Cellular Metabolic Process RNA Splicing, Via Transesterification Reactions RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Metabolic Process Chromatin Organization Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process RNA Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Intracellular Steroid Hormone Receptor Signaling Pathway Telomere Maintenance Peptidyl-amino Acid Modification Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Processing MRNA Splicing, Via Spliceosome Aromatic Compound Catabolic Process Macromolecule Biosynthetic Process Regulation Of Androgen Receptor Signaling Pathway Cytoplasmic Sequestering Of Transcription Factor Negative Regulation Of Nucleic Acid-templated Transcription
Tagcloud ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution taf15 tardbp tdp43 tremor
Tagcloud (Difference) ?		box creb cysteine damaging detail disulfides examples forkhead foxo4 give h2o2 instance intermolecular merely mini nadph o4 oxidase oxidation peroxide perturbs phenomenon redox respiration reversible signalling translating transportin ultimately	amyotrophic autosomal carriers coding conserved equivocal et ewsr1 exons export familial frontotemporal fus genotyped genotyping lobar nes neurodegeneration pathogenicity r471c relatives sequenced subject substitution taf15 tardbp tdp43 tremor
Tagcloud (Intersection) ?