TNPO1 and RGPD5

Number of citations of the paper that reports this interaction (PubMedID 12905863)
0

Data Source:
BioGRID (pull down)
HPRD (two hybrid, in vitro)

		TNPO1	RGPD5
Description		transportin 1	RANBP2 like and GRIP domain containing 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Cilium Nuclear Lumen Extracellular Exosome	Nuclear Pore Cytoplasm
	Molecular Function	RNA Binding Protein Binding Nuclear Localization Sequence Binding Small GTPase Binding Nuclear Import Signal Receptor Activity	GTPase Activator Activity Protein Binding
	Biological Process	Protein Import Into Nucleus Intracellular Protein Transport Protein Transport	NLS-bearing Protein Import Into Nucleus
Pathways		Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA Intraflagellar transport Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS		Chronic obstructive pulmonary disease ( 30804561) Factor VIII levels ( 30586737) Height ( 31562340) Hemoglobin ( 32888494) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular hemoglobin concentration ( 27863252 29403010 32888494) Mean platelet volume ( 27863252 32888494) Medication use (thyroid preparations) ( 31015401) Platelet count ( 32888494 27863252) Plateletcrit ( 32888494) Red cell distribution width ( 28957414 32888494) Serum albumin levels ( 29403010) vWF levels ( 30586737)
Interacting Genes		19 interacting genes: ELAVL1 H2BC21 H3-4 HNRNPA1 HNRNPD NUP153 NUP214 NUP98 NXF1 PABPN1 RAN RANBP2 RGPD5 RNF10 RPL23A RPL5 RPS7 SRP19 ULK2	3 interacting genes: MLLT10 RAN TNPO1
Entrez ID		3842	84220
HPRD ID		04210	04128
Ensembl ID		ENSG00000083312	ENSG00000015568
Uniprot IDs		A0A7P0TBF0 Q92973	Q99666 V9HWE4
PDB IDs		1QBK 2H4M 2OT8 2QMR 2Z5J 2Z5K 2Z5M 2Z5N 2Z5O 4FDD 4FQ3 4JLQ 4OO6 5J3V 5TQC 5YVG 5YVH 5YVI 7CYL 7VPW 8SGH
Enriched GO Terms of Interacting Partners?		Nuclear Transport Nucleocytoplasmic Transport Import Into Nucleus Nuclear Export Nuclear Inclusion Body RNA Export From Nucleus RNA Transport Nuclear Pore Nucleobase-containing Compound Transport Protein Import Into Nucleus MRNA Transport Ribonucleoprotein Complex Protein Localization To Nucleus Establishment Of Protein Localization To Organelle RNA Binding Nuclear Envelope Cellular Localization Intracellular Transport Nuclear Pore Nuclear Basket Nucleoplasm Intracellular Protein Transport Establishment Of Localization In Cell Nuclear Localization Sequence Binding Structural Constituent Of Nuclear Pore Protein Localization To Organelle Establishment Of Protein Localization Nucleus Cytosolic Ribosome Nuclear Pore Cytoplasmic Filaments Negative Regulation Of RNA Export From Nucleus Regulation Of Nucleocytoplasmic Transport Protein Transport MRNA 3'-UTR Binding Cytosol Negative Regulation Of Ubiquitin Protein Ligase Activity Intracellular Protein Localization Nuclear Pore Complex Assembly MRNA Export From Nucleus Negative Regulation Of Ubiquitin-protein Transferase Activity Nuclear Export Signal Receptor Activity Ubiquitin Ligase Inhibitor Activity Nuclear Pore Organization MRNA Binding Nuclear Periphery Regulation Of RNA Export From Nucleus Regulation Of Intracellular Transport Pore Complex Assembly Protein-containing Complex Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Poly(A)+ MRNA Export From Nucleus	Protein Import Into Nucleus Import Into Nucleus Protein Localization To Nucleus RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Nuclear Transport Nucleocytoplasmic Transport RNA Import Into Nucleus Establishment Of Protein Localization To Organelle Ribosomal Small Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Cellular Response To Mineralocorticoid Stimulus Nuclear Export Signal Receptor Activity Protein Localization To Nucleolus Pre-miRNA Binding Importin-alpha Family Protein Binding Ribosomal Subunit Export From Nucleus Chromatin Binding Intracellular Protein Transport Nuclear Import Signal Receptor Activity Manchette GTP Metabolic Process Nuclear Localization Sequence Binding Protein Localization To Organelle Flemming Body Protein Export From Nucleus Protein-containing Complex Nucleosome Binding Nuclear Lumen Mitotic Sister Chromatid Segregation Dynein Intermediate Chain Binding Positive Regulation Of Protein Import Into Nucleus Response To Mineralocorticoid Sister Chromatid Segregation Nucleolus ADP Catabolic Process Purine Ribonucleoside Diphosphate Catabolic Process Glycolytic Process Nuclear Chromosome Segregation Male Germ Cell Nucleus ADP Metabolic Process Nucleoside Diphosphate Catabolic Process Ribonucleoside Diphosphate Catabolic Process
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