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TUBB4B and TINF2
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
82
Data Source:
BioGRID
(two hybrid)
TUBB4B
TINF2
Description
tubulin beta 4B class IVb
TERF1 interacting nuclear factor 2
Image
GO Annotations
Cellular Component
Extracellular Region
Nucleus
Cytoplasm
Cytosol
Cytoskeleton
Microtubule
Axonemal Microtubule
Cilium
Microtubule Cytoskeleton
Motile Cilium
Azurophil Granule Lumen
Sperm Flagellum
Cell Projection
Intercellular Bridge
Extracellular Exosome
Mitotic Spindle
Extracellular Vesicle
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Chromosome
Perinucleolar Chromocenter
Nuclear Matrix
Nuclear Body
Shelterin Complex
Molecular Function
Nucleotide Binding
Double-stranded RNA Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
Protein Binding
GTP Binding
MHC Class I Protein Binding
Metal Ion Binding
Unfolded Protein Binding
DNA Binding
Protein Binding
Telomeric DNA Binding
Biological Process
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Microtubule-based Process
Flagellated Sperm Motility
Natural Killer Cell Mediated Cytotoxicity
Telomere Capping
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Regulation Of Telomere Maintenance Via Telomere Lengthening
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Anchoring of the basal body to the plasma membrane
Cargo trafficking to the periciliary membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
Neutrophil degranulation
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
PKR-mediated signaling
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
Polymerase switching on the C-strand of the telomere
Processive synthesis on the C-strand of the telomere
Telomere C-strand (Lagging Strand) Synthesis
Telomere C-strand synthesis initiation
Removal of the Flap Intermediate from the C-strand
DNA Damage/Telomere Stress Induced Senescence
Inhibition of DNA recombination at telomere
Drugs
Albendazole
Mebendazole
Epothilone D
Patupilone
Oxibendazole
CYT997
Phenethyl Isothiocyanate
Diseases
Revesz syndrome; Exudative retinopathy with bone marrow failure
GWAS
Leukocyte telomere length (
31171785
)
Platelet count (
29403010
)
Interacting Genes
23 interacting genes:
ACD
CDKN2A
CEBPA
DAPK1
DLEU1
DLST
ENOX2
LINC01554
NEAT1
NEDD8
OGT
POT1
PSME1
PTEN
RSPH1
SCG2
SOCS6
SOCS7
SUMO2
TERF1
TINF2
TUBG1
WEE2-AS1
91 interacting genes:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
ANXA8L1
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CSNK2A1
CTTN
DBN1
DCX
DHFR2
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
MTNR1B
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS1
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TFRC
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
Entrez ID
10383
26277
HPRD ID
04043
16056
Ensembl ID
ENSG00000188229
ENSG00000092330
Uniprot IDs
P68371
B4DFJ1
Q9BSI4
PDB IDs
7UN1
7UNG
8J07
8SH7
3BQO
3BU8
5XYF
Enriched GO Terms of Interacting Partners
?
Shelterin Complex
Nuclear Telomere Cap Complex
Telomere Capping
Telomere Assembly
Negative Regulation Of Telomere Maintenance Via Telomerase
Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance Via Telomere Lengthening
Regulation Of Proteolysis
Positive Regulation Of Telomere Maintenance
Telomere Maintenance Via Telomerase
Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Chromosome Organization
RNA-templated DNA Biosynthetic Process
Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Telomere Maintenance
Positive Regulation Of Chromosome Organization
Regulation Of Telomere Maintenance
Regulation Of Establishment Of Protein Localization To Telomere
Regulation Of Establishment Of Protein Localization To Chromosome
Telomere Organization
Telomerase Inhibitor Activity
Establishment Of Protein Localization To Telomere
Negative Regulation Of DNA Metabolic Process
Negative Regulation Of Cell Size
Telomeric D-loop Disassembly
G-rich Strand Telomeric DNA Binding
Telomeric Loop Disassembly
Protein Localization To Chromosome, Telomeric Region
Chromosome, Telomeric Region
Chromosome Organization
Organelle Organization
Protein Tag Activity
Positive Regulation Of Proteolysis
Regulation Of Proteasomal Protein Catabolic Process
Nuclear Body Organization
DNA Biosynthetic Process
SUMO Transferase Activity
Nucleus
Negative Regulation Of Metabolic Process
Meiotic Spindle Organization
Regulation Of Chromosome Organization
Protein Modification Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Cellular Component Organization
Cytosol
Extracellular Exosome
Cytoplasm
ADP Metabolic Process
Purine Ribonucleotide Catabolic Process
Ribonucleoside Diphosphate Metabolic Process
Glycolytic Process
ADP Catabolic Process
Purine Nucleotide Catabolic Process
Nucleoside Phosphate Catabolic Process
Nucleoside Diphosphate Metabolic Process
Purine Ribonucleoside Diphosphate Catabolic Process
Ribonucleoside Diphosphate Catabolic Process
Nucleoside Diphosphate Catabolic Process
Cadherin Binding
Pyruvate Metabolic Process
Nucleotide Catabolic Process
Carbohydrate Catabolic Process
Shelterin Complex
Organophosphate Catabolic Process
Glucose Metabolic Process
RNA-templated DNA Biosynthetic Process
Nuclear Telomere Cap Complex
Glucose Catabolic Process
Nucleobase-containing Compound Catabolic Process
Protein Localization To Chromosome, Telomeric Region
ATP Metabolic Process
Hexose Metabolic Process
Negative Regulation Of Telomeric D-loop Disassembly
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Telomere Capping
Nicotinamide Nucleotide Metabolic Process
Purine-containing Compound Metabolic Process
Generation Of Precursor Metabolites And Energy
Ficolin-1-rich Granule Lumen
Nucleobase-containing Small Molecule Metabolic Process
Monosaccharide Metabolic Process
Carbohydrate Derivative Catabolic Process
Phosphoglucomutase Activity
Nucleoside Metabolic Process
Protein Binding
Purine Ribonucleotide Metabolic Process
Calcium-dependent Phospholipid Binding
Cellular Response To Heat
Canonical Glycolysis
Negative Regulation Of Apoptotic Process
Negative Regulation Of Telomere Maintenance Via Telomerase
Ribonucleotide Metabolic Process
Glycolytic Process Through Glucose-6-phosphate
Glycolytic Process Through Fructose-6-phosphate
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Tagcloud (Intersection)
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