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TUBB4B and TINF2
Number of citations of the paper that reports this interaction (PMID
21044950
)
9
Data Source:
BioGRID
(two hybrid)
TUBB4B
TINF2
Gene Name
tubulin, beta 4B class IVb
TERF1 (TRF1)-interacting nuclear factor 2
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Cytoskeleton
Microtubule
Vesicle
Extracellular Vesicular Exosome
Chromosome, Telomeric Region
Nuclear Telomere Cap Complex
Nucleus
Nucleoplasm
Perinucleolar Chromocenter
Nuclear Matrix
Molecular Function
Double-stranded RNA Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
GTP Binding
MHC Class I Protein Binding
Unfolded Protein Binding
DNA Binding
Protein Binding
Telomeric DNA Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Protein Folding
Movement Of Cell Or Subcellular Component
Organelle Organization
Natural Killer Cell Mediated Cytotoxicity
Cellular Protein Metabolic Process
'de Novo' Posttranslational Protein Folding
Spindle Assembly
Protein Polymerization
Transmembrane Transport
Telomere Maintenance
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Protein ADP-ribosylation
Telomere Assembly
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Telomere Maintenance Via Telomerase
Protein Localization To Chromosome
Negative Regulation Of Epithelial Cell Proliferation
Protein Localization To Chromosome, Telomeric Region
Pathways
Transport of connexons to the plasma membrane
Hedgehog 'off' state
Formation of tubulin folding intermediates by CCT/TriC
Regulation of PLK1 Activity at G2/M Transition
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Gap junction trafficking and regulation
Recruitment of mitotic centrosome proteins and complexes
Orphan transporters
Gap junction assembly
Gap junction trafficking
Factors involved in megakaryocyte development and platelet production
Resolution of Sister Chromatid Cohesion
Mitotic G2-G2/M phases
Mitotic Metaphase and Anaphase
Adaptive Immune System
Mitotic Prometaphase
Organelle biogenesis and maintenance
Axon guidance
Separation of Sister Chromatids
Translocation of GLUT4 to the plasma membrane
G2/M Transition
L1CAM interactions
Mitotic Anaphase
Recycling pathway of L1
Recruitment of NuMA to mitotic centrosomes
M Phase
Intraflagellar transport
Post-chaperonin tubulin folding pathway
Loss of Nlp from mitotic centrosomes
MHC class II antigen presentation
Protein folding
Kinesins
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Assembly of the primary cilium
Anchoring of the basal body to the plasma membrane
Cell Cycle, Mitotic
Loss of proteins required for interphase microtubule organization from the centrosome
Signaling by Hedgehog
Chaperonin-mediated protein folding
Centrosome maturation
Telomere Maintenance
Packaging Of Telomere Ends
DNA Damage/Telomere Stress Induced Senescence
Chromosome Maintenance
Cellular Senescence
Meiotic synapsis
Drugs
Albendazole
Mebendazole
Epothilone D
Epothilone B
Diseases
GWAS
Protein-Protein Interactions
13 interactors:
ACD
CDKN2A
DLEU1
DLST
ENOX2
POT1
PSME1
SCG2
SOCS6
SOCS7
TERF1
TINF2
TUBG1
88 interactors:
ACD
ACOT7
ACTB
ADA
AFAP1L2
AIPL1
AK1
ANKMY2
ANXA4
ANXA5
APOBEC3F
APPL2
ARHGDIA
ARID3B
BAG3
BIN2
CALD1
CCDC43
CCDC9
CKB
CLK3
CPNE3
CRYGS
CTTN
DBN1
DCX
DHFRL1
DPP3
EEF1D
EIF4B
ENO2
FAM131B
FERMT3
FKBP6
GAPDH
GNMT
HNMT
HOXA3
HSP90AB1
IPO5
KCTD17
LASP1
LDHA
LGALSL
LTA4H
MAP2K3
NCDN
NOL3
NUDC
NUDCD2
OR2H1
PAGE2
PAK1IP1
PEX5
PFKP
PGM1
PGM2
PHPT1
PKM
POT1
PPP1R2
PPP6R3
PRKCB
REM2
RGS14
RPSA
SARS
SCRN2
SIAH2
STUB1
SULT1C2
TAGLN
TBL1X
TERF1
TERF2
TOMM34
TPP1
TRIM15
TRIM16
TRIP10
TUBB
TUBB4B
TXNDC17
UCHL1
VIPR1
YWHAG
ZFP36L1
ZNF790
Entrez ID
10383
26277
HPRD ID
04043
16056
Ensembl ID
ENSG00000188229
ENSG00000092330
Uniprot IDs
P68371
B4DFJ1
Q9BSI4
PDB IDs
3BQO
3BU8
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Replication
Negative Regulation Of Transferase Activity
Regulation Of Telomerase Activity
Regulation Of Telomere Maintenance
Telomere Assembly
Negative Regulation Of DNA Metabolic Process
Regulation Of DNA Replication
Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomerase Activity
Negative Regulation Of Catalytic Activity
Telomere Maintenance
Regulation Of Chromosome Organization
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Protein Kinase Activity
Protein Localization To Chromosome, Telomeric Region
Telomere Capping
Regulation Of Catalytic Activity
Negative Regulation Of Kinase Activity
Positive Regulation Of Telomerase Activity
Chromosome Organization
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Growth
Telomere Maintenance Via Telomerase
Positive Regulation Of Proteolysis
Regulation Of Proteolysis
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Protein Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Phosphorylation
Positive Regulation Of Organelle Organization
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of Peptidase Activity
Regulation Of Organelle Organization
RNA-dependent DNA Replication
Negative Regulation Of JAK-STAT Cascade
Negative Regulation Of Cell Cycle
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Telomere Maintenance
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomerase Activity
Glycolytic Process
Protection From Non-homologous End Joining At Telomere
Carbohydrate Catabolic Process
Negative Regulation Of DNA Replication
Telomere Assembly
Catabolic Process
Negative Regulation Of DNA Metabolic Process
Protein Localization To Chromosome, Telomeric Region
Negative Regulation Of Catalytic Activity
Positive Regulation Of Telomerase Activity
Pyruvate Metabolic Process
Telomere Maintenance
Telomere Maintenance Via Telomerase
Pathogenesis
Generation Of Precursor Metabolites And Energy
Glucose Metabolic Process
Positive Regulation Of Single-stranded Telomeric DNA Binding
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Negative Regulation Of Chromosome Organization
Small Molecule Metabolic Process
Organic Acid Metabolic Process
Regulation Of DNA Biosynthetic Process
Regulation Of Catalytic Activity
Carboxylic Acid Metabolic Process
Age-dependent Telomere Shortening
Telomeric Loop Formation
Nervous System Development
Regulation Of Signaling
Positive Regulation Of DNA Biosynthetic Process
Glycogen Metabolic Process
RNA-dependent DNA Replication
Nucleoside Metabolic Process
Telomere Maintenance Via Telomere Shortening
Regulation Of Signal Transduction
Hexose Metabolic Process
Cellular Process
Regulation Of DNA Replication
Monocarboxylic Acid Metabolic Process
Cellular Carbohydrate Metabolic Process
Response To Stimulus
Protein Localization To Chromosome
Organelle Organization
Telomere Maintenance Via Telomere Lengthening
Polysaccharide Metabolic Process
Tagcloud
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
terf2
terf2ip
yates
Tagcloud (Difference)
?
acd
add
broader
clustered
clustering
convincingly
correction
cosegregated
ends
families
fisher
germline
inactivating
lod
logarithm
melanoma
nonsense
pot1
predispose
probands
q320x
r364x
shelterin
tailed
terf1
terf2
terf2ip
yates
Tagcloud (Intersection)
?