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TUBB4B and DLEU1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
HPRD
(two hybrid)
TUBB4B
DLEU1
Gene Name
tubulin, beta 4B class IVb
deleted in lymphocytic leukemia 1 (non-protein coding)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Cytosol
Cytoskeleton
Microtubule
Vesicle
Extracellular Vesicular Exosome
Molecular Function
Double-stranded RNA Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
GTP Binding
MHC Class I Protein Binding
Unfolded Protein Binding
Biological Process
G2/M Transition Of Mitotic Cell Cycle
Mitotic Cell Cycle
Protein Folding
Movement Of Cell Or Subcellular Component
Organelle Organization
Natural Killer Cell Mediated Cytotoxicity
Cellular Protein Metabolic Process
'de Novo' Posttranslational Protein Folding
Spindle Assembly
Protein Polymerization
Transmembrane Transport
Pathways
Transport of connexons to the plasma membrane
Hedgehog 'off' state
Formation of tubulin folding intermediates by CCT/TriC
Regulation of PLK1 Activity at G2/M Transition
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Gap junction trafficking and regulation
Recruitment of mitotic centrosome proteins and complexes
Orphan transporters
Gap junction assembly
Gap junction trafficking
Factors involved in megakaryocyte development and platelet production
Resolution of Sister Chromatid Cohesion
Mitotic G2-G2/M phases
Mitotic Metaphase and Anaphase
Adaptive Immune System
Mitotic Prometaphase
Organelle biogenesis and maintenance
Axon guidance
Separation of Sister Chromatids
Translocation of GLUT4 to the plasma membrane
G2/M Transition
L1CAM interactions
Mitotic Anaphase
Recycling pathway of L1
Recruitment of NuMA to mitotic centrosomes
M Phase
Intraflagellar transport
Post-chaperonin tubulin folding pathway
Loss of Nlp from mitotic centrosomes
MHC class II antigen presentation
Protein folding
Kinesins
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Assembly of the primary cilium
Anchoring of the basal body to the plasma membrane
Cell Cycle, Mitotic
Loss of proteins required for interphase microtubule organization from the centrosome
Signaling by Hedgehog
Chaperonin-mediated protein folding
Centrosome maturation
Drugs
Albendazole
Mebendazole
Epothilone D
Epothilone B
Diseases
GWAS
Multiple sclerosis (
21833088
)
Protein-Protein Interactions
13 interactors:
ACD
CDKN2A
DLEU1
DLST
ENOX2
POT1
PSME1
SCG2
SOCS6
SOCS7
TERF1
TINF2
TUBG1
19 interactors:
ABCD4
ABCF3
ARL8B
CCDC90B
COPS6
EEF1A1
EEF1G
GDF9
KAT5
KIAA1377
MED31
PSMA1
SETDB1
SHMT1
TLE1
TP53
TUBB4B
UBR1
UTP14A
Entrez ID
10383
10301
HPRD ID
04043
16150
Ensembl ID
ENSG00000188229
ENSG00000176124
Uniprot IDs
P68371
PDB IDs
Enriched GO Terms of Interacting Partners
?
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Replication
Negative Regulation Of Transferase Activity
Regulation Of Telomerase Activity
Regulation Of Telomere Maintenance
Telomere Assembly
Negative Regulation Of DNA Metabolic Process
Regulation Of DNA Replication
Regulation Of DNA Biosynthetic Process
Negative Regulation Of Telomerase Activity
Negative Regulation Of Catalytic Activity
Telomere Maintenance
Regulation Of Chromosome Organization
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Cellular Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Biosynthetic Process
Telomere Maintenance Via Telomere Lengthening
Negative Regulation Of Protein Kinase Activity
Protein Localization To Chromosome, Telomeric Region
Telomere Capping
Regulation Of Catalytic Activity
Negative Regulation Of Kinase Activity
Positive Regulation Of Telomerase Activity
Chromosome Organization
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Regulation Of Growth
Telomere Maintenance Via Telomerase
Positive Regulation Of Proteolysis
Regulation Of Proteolysis
Positive Regulation Of Telomere Maintenance
Negative Regulation Of Protein Phosphorylation
Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Biosynthetic Process
Regulation Of Protein Metabolic Process
Negative Regulation Of Phosphorylation
Positive Regulation Of Organelle Organization
Positive Regulation Of Endopeptidase Activity
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of Peptidase Activity
Regulation Of Organelle Organization
RNA-dependent DNA Replication
Negative Regulation Of JAK-STAT Cascade
Negative Regulation Of Cell Cycle
Positive Regulation Of Cellular Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator
Signal Transduction In Response To DNA Damage
DNA Damage Response, Signal Transduction Resulting In Transcription
Signal Transduction By P53 Class Mediator
Negative Regulation Of Fibroblast Proliferation
Viral Process
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Mitotic G1 DNA Damage Checkpoint
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Mitotic Cell Cycle Process
Negative Regulation Of Macromitophagy
Cellular Response To Leucine
Oocyte Growth
Oligodendrocyte Apoptotic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Water-soluble Vitamin Metabolic Process
Mitotic Cell Cycle
Gene Expression
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Mitotic DNA Damage Checkpoint
Negative Regulation Of Helicase Activity
Regulation Of Fibroblast Proliferation
Regulation Of Cell Cycle Arrest
Cell Cycle
Cellular Metabolic Process
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Mitotic DNA Integrity Checkpoint
Nitrogen Compound Metabolic Process
Protein Tetramerization
L-serine Catabolic Process
Regulation Of Progesterone Secretion
Vitamin Metabolic Process
Carnitine Biosynthetic Process
Positive Regulation Of Protein Modification Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Spindle Organization
Positive Regulation Of Thymocyte Apoptotic Process
Positive Regulation Of Cell Aging
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Regulation Of Cell Cycle G1/S Phase Transition
Metabolic Process
Notch Signaling Pathway
Transcription, DNA-templated
Tagcloud
?
10q23
11q22
12p13
13q14
17p13
21q22
2p23
5q32
6q21
7p12
7q21
8q24
9p13
9p21
9p24
acgh
dleu2
ebf1
ikzf1
imbalances
interrogate
mir145a
mir146a
mir15a
mlpa
pax5
probemix
uncovering
undetected
Tagcloud (Difference)
?
10q23
11q22
12p13
13q14
17p13
21q22
2p23
5q32
6q21
7p12
7q21
8q24
9p13
9p21
9p24
acgh
dleu2
ebf1
ikzf1
imbalances
interrogate
mir145a
mir146a
mir15a
mlpa
pax5
probemix
uncovering
undetected
Tagcloud (Intersection)
?