CDKN1B and CDK4

  • Number of citations of the paper that reports this interaction (PMID 10908655)
  • 45
  • Data Source:
  • HPRD (in vitro, in vivo)

CDKN1B

CDK4

Gene Name cyclin-dependent kinase inhibitor 1B (p27, Kip1) cyclin-dependent kinase 4
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Systemic lupus erythematosus ( 23273568)
  • Celiac disease and Rheumatoid arthritis ( 21383967)
Protein-Protein Interactions 62 interactors: ABL1 AKT1 ARHGDIA CAMK1 CASP8 CCNA1 CCNA2 CCNB1 CCND1 CCND2 CCND3 CCNE2 CDC34 CDK2 CDK3 CDK4 CDK5 CKS1B COPS5 CUL1 CUL4A GRB2 HIST1H1A HIST1H1B IRF1 KAT2B KPNA1 KPNA3 KPNA4 KPNA5 KPNA6 LYN MAPK10 MCM7 NUP50 PIN1 PSMB1 RCHY1 RNF123 RPS6KA1 SGK1 SKP1 SKP2 SPDYA SRC STMN1 TRAF2 TSC2 UBAC1 UBB UBE2B UBE2D2 UBE3A UCHL1 XPO1 YES1 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ 90 interactors: ANKRD12 ANXA7 APLP1 APP ARID4A ATP5B BAG6 BCL11A BIRC5 BMPR1B BRCA1 CAMK1 CAPNS1 CCND1 CCND2 CCND3 CDC37 CDC45 CDC6 CDC7 CDKN1A CDKN1B CDKN1C CDKN2A CDKN2B CDKN2C CDKN2D CEBPA CIB1 CNOT7 DAZAP2 DDAH2 DUSP9 FOXM1 GLI1 H1F0 HIST1H1A HIST1H1D HMGXB3 HOOK1 IFI27 IL15RA LUC7L2 MAPRE2 MARCKS MCM2 MYC MYOD1 MZF1 NCOA2 NOL12 ORC3 OTX2 PGD PKM POLD1 PPP2R1B PRKAR1A PSMD10 PTMA QARS RB1 RBL1 RBL2 RFC1 RFC4 RPL34 SENP3 SERTAD1 SETDB1 SHOX2 SKP1 SLBP SMAD2 SMAD3 SNCA TGFBR1 TK1 TRMT2A TSPYL2 UBTF UHRF2 VTA1 WDR33 ZBTB16 ZNF101 ZNF219 ZNF335 ZNF655 ZSCAN1
Entrez ID 1027 1019
HPRD ID 02867 00447
Ensembl ID ENSG00000111276 ENSG00000135446
Uniprot IDs P46527 Q6I9V6 P11802 Q6LC83
PDB IDs 1H27 1JSU 2AST 1LD2 2W96 2W99 2W9F 2W9Z 3G33
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aggregated  anaplastic  atc  braf  cdkn2c  ctnnb1  eif1ax  exclusive  exome  harbored  hypermutator  landscape  mismatch  mlh  mlh1  mlh3  msh5  msh6  mutational  mutually  nf1  nf2  nras  ontology  pik3ca  ret  unresponsive  ush2a  v600e 
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  p15  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
Tagcloud (Difference) ?
aggregated  anaplastic  atc  braf  cdkn2c  ctnnb1  eif1ax  exclusive  exome  harbored  hypermutator  landscape  mismatch  mlh  mlh1  mlh3  msh5  msh6  mutational  mutually  nf1  nf2  nras  ontology  pik3ca  ret  unresponsive  ush2a  v600e 
aberrantly  acetylglucosaminyltransferase  antigens  bage  ctl  ecto  fig  fm3  fm57  gage  gp100  immunogenic  immunogenicity  in4  maa  mage  mart  melan  melanocyte  melanomas  p15  pbl  permitted  pointing  prame  ref  tab  trp  tyrosinase  uncloned 
Tagcloud (Intersection) ?