ILF3 and GDF9

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ILF3	GDF9
Gene Name		interleukin enhancer binding factor 3, 90kDa	growth differentiation factor 9
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex	Extracellular Space Cytoplasm
	Molecular Function	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding	Cytokine Activity Transforming Growth Factor Beta Receptor Binding Growth Factor Activity
	Biological Process	Transcription, DNA-templated Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus	Oocyte Growth Transforming Growth Factor Beta Receptor Signaling Pathway Female Gamete Generation Positive Regulation Of Cell Proliferation Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Cell Growth BMP Signaling Pathway Regulation Of Apoptotic Process Regulation Of MAPK Cascade Cell Development SMAD Protein Signal Transduction Regulation Of Progesterone Secretion
Pathways
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		26 interactors: DHX9 EIF2AK2 ERG FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PRMT1 RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIP6 XAB2 XPO5 ZNF346 ZNF830	45 interactors: ACVR2A ADPGK ANXA7 APLP1 BMP15 BMPR1A BMPR1B BMPR2 BTBD2 CCDC53 CDKN1A CDKN2C CRELD1 DLEU1 DNM2 FOXG1 FXYD6 GADD45G ILF3 KDM1A KIF22 LSM3 MOB4 MPHOSPH6 MYCBP NDUFB9 ORAI2 PABPC4 PAFAH1B3 PCDHA4 PCYT2 PMF1 PRKRA PSMD11 RAB27A RSRC1 S100A8 SAT1 SERPINB9 SMN1 SNRPG STRN4 TDGF1 TK1 TRIB3
Entrez ID		3609	2661
HPRD ID		04420	03560
Ensembl ID		ENSG00000129351	ENSG00000164404
Uniprot IDs		Q12906	B4DXG3 O60383
PDB IDs		2L33 3P1X
Enriched GO Terms of Interacting Partners?		MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Protein Import Into Nucleus Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Negative Regulation Of Viral Genome Replication Regulation Of Protein Localization To Nucleus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Potassium Ion Export Regulation Of Nucleocytoplasmic Transport In Utero Embryonic Development Regulation Of RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Intracellular Protein Transport Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Regulation Of Hematopoietic Stem Cell Differentiation Oocyte Growth Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cellular Response To Stress Cellular Macromolecular Complex Assembly Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Intestinal Epithelial Structure Maintenance Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation	BMP Signaling Pathway Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Bone Mineralization Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of Protein Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Chondrocyte Proliferation Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Developmental Process Regulation Of Bone Mineralization Positive Regulation Of Osteoblast Differentiation Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Anatomical Structure Development Positive Regulation Of Protein Modification Process Nucleobase-containing Compound Metabolic Process System Development Cellular Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Ossification Nitrogen Compound Metabolic Process Cellular Metabolic Process Positive Regulation Of Protein Metabolic Process Multicellular Organismal Development Positive Regulation Of Signal Transduction Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Immune System Process Regulation Of Cell Death RNA Metabolic Process RNA Processing Phosphate-containing Compound Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Phosphorylation Regulation Of Osteoblast Differentiation Gene Expression Negative Regulation Of Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Transferase Activity Regulation Of Phosphorus Metabolic Process Positive Regulation Of Protein Phosphorylation Regulation Of Gene Expression Regulation Of Phosphorylation Regulation Of Cell Growth Organ Development Gastrulation Positive Regulation Of Metabolic Process
Tagcloud ?		acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored	3h bmp bmp15 bmpr2 decapentaplegic differing granulosa incorporation involves jnk jun kb mapk morphogenetic mothers ovine p3h pathways signalling sma smad smad1 smad2 steroid stimulate synergistic synergistically thymidine utilised
Tagcloud (Difference) ?		acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored	3h bmp bmp15 bmpr2 decapentaplegic differing granulosa incorporation involves jnk jun kb mapk morphogenetic mothers ovine p3h pathways signalling sma smad smad1 smad2 steroid stimulate synergistic synergistically thymidine utilised
Tagcloud (Intersection) ?