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ILF3 and DHX9
Number of citations of the paper that reports this interaction (PMID
12946349
)
15
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
ILF3
DHX9
Gene Name
interleukin enhancer binding factor 3, 90kDa
DEAH (Asp-Glu-Ala-His) box helicase 9
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Mitochondrion
Membrane
Ribonucleoprotein Complex
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Centrosome
Cytosol
Membrane
Ribonucleoprotein Complex
Cytoplasmic Ribonucleoprotein Granule
CRD-mediated MRNA Stability Complex
Molecular Function
DNA Binding
RNA Binding
Double-stranded RNA Binding
Protein Binding
Poly(A) RNA Binding
RNA Polymerase II Transcription Factor Binding
DNA Binding
RNA Helicase Activity
ATP-dependent DNA Helicase Activity
ATP-dependent RNA Helicase Activity
Protein Binding
ATP Binding
Poly(A) RNA Binding
Biological Process
Transcription, DNA-templated
Protein Phosphorylation
Negative Regulation Of Translation
Negative Regulation Of Viral Genome Replication
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Defense Response To Virus
MRNA Splicing, Via Spliceosome
Osteoblast Differentiation
RNA Processing
Circadian Rhythm
RNA Splicing
Gene Expression
Positive Regulation Of Type I Interferon Production
DNA Duplex Unwinding
Cellular Response To Heat
Innate Immune Response
CRD-mediated MRNA Stabilization
Pathways
mRNA Splicing
Toll Like Receptor 7/8 (TLR7/8) Cascade
Toll Like Receptor TLR6:TLR2 Cascade
RIP-mediated NFkB activation via ZBP1
DEx/H-box helicases activate type I IFN and inflammatory cytokines production
Toll Like Receptor TLR1:TLR2 Cascade
Activated TLR4 signalling
MyD88 cascade initiated on plasma membrane
Toll Like Receptor 5 (TLR5) Cascade
ZBP1(DAI) mediated induction of type I IFNs
MyD88 dependent cascade initiated on endosome
MyD88:Mal cascade initiated on plasma membrane
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
Toll Like Receptor 9 (TLR9) Cascade
Innate Immune System
Processing of Capped Intron-Containing Pre-mRNA
TRIF-mediated TLR3/TLR4 signaling
Cytosolic sensors of pathogen-associated DNA
mRNA Splicing - Major Pathway
MyD88-independent cascade
Toll Like Receptor 2 (TLR2) Cascade
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Toll-Like Receptors Cascades
Toll Like Receptor 10 (TLR10) Cascade
Toll Like Receptor 4 (TLR4) Cascade
Toll Like Receptor 3 (TLR3) Cascade
TRAF6 mediated NF-kB activation
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
Drugs
Diseases
GWAS
Obesity-related traits (
23251661
)
Protein-Protein Interactions
26 interactors:
DHX9
EIF2AK2
ERG
FUS
GDF9
HNRNPH2
IL7R
KRTAP4-12
LNX1
MAGEA11
MDFI
NDRG1
PLSCR1
PRMT1
RBM5
RBPMS
RNF113A
SF1
SF3B4
SMN1
SNRPC
TRIP6
XAB2
XPO5
ZNF346
ZNF830
40 interactors:
ACTA1
AKAP8L
APBB1
BRCA1
DDX20
DDX5
EIF2AK2
EWSR1
GEMIN2
GEMIN4
GTF2B
H2AFX
HDLBP
HNRNPC
HNRNPK
IL7R
ILF3
JUN
KHDRBS1
MBD2
MGEA5
NXF1
PCNA
POLR2A
PRMT1
PRPF40A
PRPF8
RBM4
RELA
SMN1
SMN2
SNRPB
SNRPB2
SRPK1
SSRP1
STAU1
TBP
TOP2A
UBE2I
YWHAQ
Entrez ID
3609
1660
HPRD ID
04420
04386
Ensembl ID
ENSG00000129351
ENSG00000135829
Uniprot IDs
Q12906
B3KU66
Q08211
PDB IDs
2L33
3P1X
3LLM
3VYX
3VYY
Enriched GO Terms of Interacting Partners
?
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
RNA Splicing
RNA Processing
MRNA Processing
MRNA Metabolic Process
Gene Expression
RNA Metabolic Process
Spliceosomal Complex Assembly
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Regulation Of Gene Expression
Regulation Of Female Gonad Development
Ribonucleoprotein Complex Biogenesis
Regulation Of Hematopoietic Progenitor Cell Differentiation
Cellular Metabolic Process
Regulation Of Protein Import Into Nucleus
Spliceosomal SnRNP Assembly
Regulation Of Nitrogen Compound Metabolic Process
MRNA Splice Site Selection
Negative Regulation Of Viral Genome Replication
Regulation Of Protein Localization To Nucleus
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Evasion Or Tolerance By Virus Of Host Immune Response
Negative Regulation Of Potassium Ion Export
Regulation Of Nucleocytoplasmic Transport
In Utero Embryonic Development
Regulation Of RNA Metabolic Process
Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of Intracellular Protein Transport
Regulation Of Heart Rate By Hormone
Interleukin-7-mediated Signaling Pathway
Regulation Of Hematopoietic Stem Cell Differentiation
Oocyte Growth
Regulation Of Viral Genome Replication
Negative Regulation Of Viral Process
Cellular Response To Stress
Cellular Macromolecular Complex Assembly
Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity
Intestinal Epithelial Structure Maintenance
Evasion Or Tolerance Of Host Defenses By Virus
Regulation Of Metabolic Process
Regulation Of MRNA Processing
Regulation Of Transcription Factor Import Into Nucleus
Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
MRNA Processing
RNA Splicing
MRNA Metabolic Process
RNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
Nucleobase-containing Compound Metabolic Process
RNA Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Gene Expression
Spliceosomal SnRNP Assembly
Nitrogen Compound Metabolic Process
Regulation Of Viral Process
Regulation Of Viral Genome Replication
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Viral Process
Positive Regulation Of DNA Metabolic Process
Regulation Of Gene Expression
Ribonucleoprotein Complex Assembly
Viral Process
Cellular Metabolic Process
Regulation Of RNA Metabolic Process
Negative Regulation Of Gene Expression
Positive Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Cellular Macromolecular Complex Assembly
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Transcription, DNA-templated
Cellular Macromolecule Biosynthetic Process
Positive Regulation Of Cellular Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Macromolecule Biosynthetic Process
Negative Regulation Of RNA Biosynthetic Process
Transcription, DNA-templated
Regulation Of Metabolic Process
Positive Regulation Of Metabolic Process
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Transcription Elongation From RNA Polymerase II Promoter
Chromosome Organization
Positive Regulation Of Response To DNA Damage Stimulus
Negative Regulation Of Viral Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Viral Genome Replication
Tagcloud
?
acting
analogues
axis
cll
cytotoxicity
dca
dichloroacetate
emphasize
exhibits
harboring
hl
indeed
invariably
knocking
leukemic
lymphocytic
maver
mec
mediating
merits
options
p21
p53mutated
p53null
p53wild
proteomic
purine
sirnas
underscored
Tagcloud (Difference)
?
acting
analogues
axis
cll
cytotoxicity
dca
dichloroacetate
emphasize
exhibits
harboring
hl
indeed
invariably
knocking
leukemic
lymphocytic
maver
mec
mediating
merits
options
p21
p53mutated
p53null
p53wild
proteomic
purine
sirnas
underscored
Tagcloud (Intersection)
?