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HNRNPF and POLR2A
Number of citations of the paper that reports this interaction (PubMedID
10620016
)
0
Data Source:
HPRD
(in vivo)
HNRNPF
POLR2A
Description
heterogeneous nuclear ribonucleoprotein F
RNA polymerase II subunit A
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Spliceosomal Complex
Cytosol
Plasma Membrane
Membrane
Synapse
Catalytic Step 2 Spliceosome
Ribonucleoprotein Complex
DNA-directed RNA Polymerase Complex
Prp19 Complex
Nucleus
Nucleoplasm
RNA Polymerase II, Core Complex
Chromosome
Nucleolus
Cytoplasm
Molecular Function
Nucleic Acid Binding
RNA Binding
Single-stranded RNA Binding
Protein Binding
Magnesium Ion Binding
Nucleic Acid Binding
DNA Binding
RNA Binding
DNA-directed RNA Polymerase Activity
RNA-directed RNA Polymerase Activity
Protein Binding
Zinc Ion Binding
Transferase Activity
Nucleotidyltransferase Activity
Hydrolase Activity
Kinase Binding
Ubiquitin Protein Ligase Binding
5'-3' RNA Polymerase Activity
Metal Ion Binding
Microfibril Binding
Promoter-specific Chromatin Binding
Biological Process
MRNA Splicing, Via Spliceosome
RNA Processing
MRNA Processing
RNA Splicing
Regulation Of RNA Splicing
RNA-templated Transcription
DNA-templated Transcription
DNA-templated Transcription Termination
Regulation Of DNA-templated Transcription
Transcription By RNA Polymerase II
Transcription Elongation By RNA Polymerase II
Positive Regulation Of Gene Expression
Positive Regulation Of RNA Splicing
MRNA Transcription By RNA Polymerase II
Pathways
FGFR2 alternative splicing
mRNA Splicing - Major Pathway
Processing of Capped Intron-Containing Pre-mRNA
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
HIV Transcription Initiation
RNA Polymerase II HIV Promoter Escape
Transcription of the HIV genome
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
Viral Messenger RNA Synthesis
MicroRNA (miRNA) biogenesis
Transcriptional regulation by small RNAs
PIWI-interacting RNA (piRNA) biogenesis
Activation of anterior HOX genes in hindbrain development during early embryogenesis
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase II Promoter Escape
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE
Signaling by FGFR2 IIIa TM
Estrogen-dependent gene expression
Inhibition of DNA recombination at telomere
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
Antisaccade task score (
31596458
)
Atrial fibrillation (
29892015
)
Brain morphology (MOSTest) (
32665545
)
Central corneal thickness (
29760442
)
Heel bone mineral density (
30598549
)
Mean corpuscular hemoglobin concentration (
32888494
)
Mean platelet volume (
32888494
)
Myopia (
27182965
)
Parkinson's disease progression (cognitive) (
33958783
)
Refractive error (
32231278
)
Spherical equivalent or myopia (age of diagnosis) (
29808027
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Interacting Genes
156 interacting genes:
AKIRIN2
APOBEC1
ATN1
ATP23
AURKA
BBS2
C10orf55
C1orf94
CCDC33
CPSF7
DSCAM
DUX4
DZIP3
EIF4ENIF1
ERG
FAM86C1P
HNRNPA0
HNRNPH1
HNRNPH3
HNRNPM
HNRNPUL1
HSFY1
HYPK
IKZF3
INCA1
IQCE
KLF1
KLF15
KPRP
KRT75
KRTAP7-1
LASP1
LINC01554
LNX1
MIR1-1
MIR1-2
MIR106A
MIR106B
MIR107
MIR10B
MIR122
MIR128-1
MIR128-2
MIR138-1
MIR138-2
MIR140
MIR141
MIR143
MIR145
MIR155
MIR15A
MIR15B
MIR16-1
MIR16-2
MIR17
MIR18A
MIR18B
MIR199A1
MIR199A2
MIR19A
MIR19B1
MIR19B2
MIR200A
MIR200B
MIR200C
MIR205
MIR206
MIR20A
MIR20B
MIR21
MIR214
MIR221
MIR222
MIR25
MIR29A
MIR29B1
MIR29B2
MIR29C
MIR31
MIR34A
MIR34B
MIR34C
MIR363
MIR429
MIR451A
MIR7-1
MIR7-2
MIR7-3
MIR9-1
MIR9-2
MIR9-3
MIR92A1
MIR92A2
MIR93
MIR98
MIRLET7A1
MIRLET7A2
MIRLET7A3
MIRLET7B
MIRLET7C
MIRLET7D
MIRLET7E
MIRLET7F1
MIRLET7F2
MIRLET7G
MIRLET7I
MRPL17
MSI1
NCBP1
NCBP2
NDRG1
NFKBID
NUDT16L1
OGT
PATZ1
PDLIM7
POLR2A
PROP1
PRPF40A
PRR22
PRR32
PRR34
RBFOX1
RBFOX2
RBM4
REL
RNF10
RNF26
RUSC1
SF1
SF3B4
SLAIN1
SMUG1
SNRPC
SORBS3
SPATA8
SUMO2
SUMO4
TENT5B
TFG
TGM2
TGM7
TLE5
TOE1
TRIB3
TRIM14
TXNL4A
UNKL
USP54
VAV2
VGLL1
VPS37C
ZBTB32
ZNF581
ZNF689
ZNF764
103 interacting genes:
ABL1
ACTB
ACTL6A
ATM
BARD1
BRCA1
CALCOCO1
CALCOCO2
CASP10
CCNH
CCNK
CCNL2
CCNT1
CDC14A
CDK12
CDK8
CDK9
CPSF1
CPSF2
CPSF3
CREBBP
CSH2
CSNK2A1
CSTF1
CSTF2
CTCF
CTDP1
CTDSP1
CTDSP2
DHX9
EIF4ENIF1
ELL
ERCC5
ERCC6
ERCC8
ERG
ESR1
FUS
GRB2
GTF2B
GTF2H4
H1-2
HNRNPF
HTATSF1
IFTAP
ITCH
IWS1
KAT2B
KLK2
KMT2D
LEO1
MCM3
MED21
MNAT1
MYH6
NEDD4
NONO
NR0B2
NSD1
OTUD5
PCIF1
PHF8
PIN1
POLR2C
POLR2D
POLR2E
POLR2F
POLR2G
POLR2H
POLR2L
PPIG
PPP1CA
PPP2CA
PQBP1
PRMT5
PRPF19
PTEN
RNF10
SAFB
SKP2
SMN1
SMN2
SMURF1
SNAR-B2
SND1
SUB1
SUMO2
SUPT5H
TAF10
TCEA1
TCERG1
TDRD3
TRAK1
TRAM2
TTK
U2AF2
UBE2L3
UPF1
VDR
XAB2
XRCC5
ZC3H4
ZNF74
Entrez ID
3185
5430
HPRD ID
03023
08916
Ensembl ID
ENSG00000169813
ENSG00000181222
Uniprot IDs
P52597
A0AAG2TJB2
P24928
PDB IDs
2HGL
2HGM
2HGN
2KFY
2KG0
2KG1
3TFY
2GHQ
2GHT
2LTO
3D9K
3D9L
3D9M
3D9N
3D9O
3D9P
4JXT
5IY6
5IY7
5IY8
5IY9
5IYA
5IYB
5IYC
5IYD
5M3H
5M3J
6DRD
6F5P
6G0R
6IC8
6IC9
6O9L
6Q5Y
6XKB
6XRE
7EGB
7EGC
7LBM
7YCX
7Z1K
7Z42
8PM0
8PNP
8PNQ
8R3K
8R3L
8R60
8R65
9B9L
9EHZ
9EI1
9EI2
9EI3
9EI4
Enriched GO Terms of Interacting Partners
?
MiRNA-mediated Post-transcriptional Gene Silencing
Regulatory NcRNA-mediated Post-transcriptional Gene Silencing
Post-transcriptional Gene Silencing
RISC Complex
Regulatory NcRNA-mediated Gene Silencing
MRNA Base-pairing Post-transcriptional Repressor Activity
Post-transcriptional Regulation Of Gene Expression
Negative Regulation Of Gene Expression
MiRNA-mediated Gene Silencing By Inhibition Of Translation
MRNA 3'-UTR Binding
Negative Regulation Of Macromolecule Biosynthetic Process
MiRNA-mediated Gene Silencing By MRNA Destabilization
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Negative Regulation Of Metabolic Process
Extracellular Vesicle
Negative Regulation Of Translation
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
MRNA Destabilization
Positive Regulation Of MRNA Metabolic Process
Positive Regulation Of MRNA Catabolic Process
RNA Destabilization
Regulation Of Macromolecule Metabolic Process
Regulation Of Translation
Negative Regulation Of Vascular Endothelial Growth Factor Production
Regulation Of MRNA Stability
Regulation Of MRNA Metabolic Process
Negative Regulation Of Cell Migration
Regulation Of RNA Stability
Negative Regulation Of Cytokine Production
Negative Regulation Of Cell Motility
Negative Regulation Of Angiogenesis
Negative Regulation Of Vasculature Development
Regulation Of Metabolic Process
Negative Regulation Of Locomotion
Regulation Of Angiogenesis
Regulation Of Vasculature Development
Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Endothelial Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Endothelial Cell Migration
Negative Regulation Of Blood Vessel Endothelial Cell Migration
Negative Regulation Of Developmental Process
Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Negative Regulation Of Multicellular Organismal Process
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Cytokine Production
Regulation Of Cell Migration Involved In Sprouting Angiogenesis
Nucleoplasm
Nucleic Acid Metabolic Process
Nucleus
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Macromolecule Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Transcription By RNA Polymerase II
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
DNA-templated Transcription
Regulation Of Primary Metabolic Process
Regulation Of Transcription By RNA Polymerase II
Macromolecule Biosynthetic Process
Regulation Of Gene Expression
Regulation Of Macromolecule Metabolic Process
MRNA Metabolic Process
Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Regulation Of Metabolic Process
Positive Regulation Of DNA-templated Transcription
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
DNA-templated Transcription Elongation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Biosynthetic Process
Positive Regulation Of DNA-templated Transcription, Elongation
Regulation Of DNA Metabolic Process
DNA Repair
Regulation Of Cell Cycle
Regulation Of DNA Repair
DNA Metabolic Process
Regulation Of DNA-templated Transcription Elongation
Positive Regulation Of Transcription Elongation By RNA Polymerase II
MRNA Processing
RNA Polymerase II, Core Complex
DNA Damage Response
Transcription Elongation By RNA Polymerase II
Chromatin Binding
Regulation Of Cell Cycle Process
RNA Polymerase Binding
Regulation Of Transcription Elongation By RNA Polymerase II
Chromatin Organization
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
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