HNRNPUL1 and WWP2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		HNRNPUL1	WWP2
Gene Name		heterogeneous nuclear ribonucleoprotein U-like 1	WW domain containing E3 ubiquitin protein ligase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Ribonucleoprotein Complex	Ubiquitin Ligase Complex Nucleus Cytoplasm Membrane Extracellular Vesicular Exosome
	Molecular Function	RNA Binding Protein Binding Enzyme Binding Poly(A) RNA Binding	RNA Polymerase II Transcription Factor Binding Ubiquitin-protein Transferase Activity Protein Binding Transcription Factor Binding Ligase Activity
	Biological Process	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing RNA Splicing Response To Virus Gene Expression	Negative Regulation Of Transcription From RNA Polymerase II Promoter Cellular Protein Modification Process Negative Regulation Of Gene Expression Protein Ubiquitination Negative Regulation Of Transporter Activity Regulation Of Ion Transmembrane Transport Regulation Of Membrane Potential Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Viral Entry Into Host Cell Negative Regulation Of Protein Transport Protein Autoubiquitination Protein K63-linked Ubiquitination Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS			IgE levels ( 23146381)
Protein-Protein Interactions		46 interactors: BRD7 C14orf1 CRMP1 DZIP3 EP300 ERG EWSR1 GIT2 HNRNPF HNRNPH2 HNRNPH3 IL7R ITCH MAPK1IP1L MARS MED31 NEDD4 NXF1 NXF2 NXF3 PIAS4 PPIL1 PRMT1 PRMT2 PRPF40A RBM22 RBM4 RBM4B ROPN1 RPA1 RPA2 SF1 SF3B4 SMN1 SMN2 SNRPB2 SNRPC SORBS3 SRSF9 TGM2 TLX3 TP53 TP53BP2 VPS37C WWP2 ZNF207	53 interactors: ANKRD44 ARRDC1 ATN1 CDC34 CLCN5 CPSF6 DAG1 DIDO1 EGR2 EWSR1 FAM189A2 FBXL18 HNRNPUL1 IL2RG IL6R LGALS9B NDFIP2 PAIP1 PDLIM7 POLR2A POU5F1 RASA1 RNF11 RUSC1 SCAMP3 SCN5A SCNN1A SCNN1B SCNN1G SF1 SFTPC SMAD3 SMAD7 SNRPC SPG20 TFAP2A TNK2 TP53BP2 TRAF4 UBC UBE2D2 UBE2D3 UBE2E1 UBE2E3 UBE2J2 UBE2K UBE2L3 USP7 VASP VPS37C WBP1 WBP2 WIPF1
Entrez ID		11100	11060
HPRD ID		10428	03812
Ensembl ID		ENSG00000105323	ENSG00000198373
Uniprot IDs		B7Z4B8 Q9BUJ2	B4DHF6 O00308
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Spliceosomal Complex Assembly Nitrogen Compound Metabolic Process Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process MRNA Export From Nucleus Negative Regulation Of Mitotic Cell Cycle Phase Transition Nucleocytoplasmic Transport Nuclear Transport RNA Export From Nucleus Regulation Of RNA Metabolic Process Entrainment Of Circadian Clock By Photoperiod Cellular Metabolic Process Photoperiodism Entrainment Of Circadian Clock Ribonucleoprotein Complex Assembly Regulation Of Cellular Response To Heat Protein K63-linked Ubiquitination DNA Recombinase Assembly Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Metabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Viral Process Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cellular Metabolic Process MRNA Transport Regulation Of Cell Cycle Phase Transition Nuclear Export Spliceosomal SnRNP Assembly Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine MRNA Splice Site Selection Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Gene Expression Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition RNA Transport	Protein Polyubiquitination Protein K48-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Ubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Response To Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteasomal Protein Catabolic Process Transcription Initiation From RNA Polymerase II Promoter Excretion Response To Organic Substance DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cellular Protein Metabolic Process Protein K11-linked Ubiquitination Sodium Ion Homeostasis Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Gene Expression Positive Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Metabolic Process RNA Metabolic Process Transcription, DNA-templated Regulation Of Ubiquitin-protein Transferase Activity Cellular Response To Stimulus Positive Regulation Of Ossification Regulation Of Ossification RNA Biosynthetic Process Regulation Of Protein Ubiquitination Apoptotic Signaling Pathway Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Regulation Of Cellular Protein Metabolic Process Viral Process Apoptotic Process Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Protein Catabolic Process RNA Processing Multicellular Organismal Water Homeostasis Programmed Cell Death Negative Regulation Of Transcription By Competitive Promoter Binding Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Proteolysis Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?			accelerating anticancer biomarker cascade catalyzes contributes counterparts deleted dramatic e3 encodes final homologue ligase ligases malignancies member nedd4 neoplastic oscc osccs pi3k promotion pten ten tensin tumoral ubiquitination
Tagcloud (Difference) ?			accelerating anticancer biomarker cascade catalyzes contributes counterparts deleted dramatic e3 encodes final homologue ligase ligases malignancies member nedd4 neoplastic oscc osccs pi3k promotion pten ten tensin tumoral ubiquitination
Tagcloud (Intersection) ?